DTC genetic testing: Pendulum swings and policy paradoxes

Clinical Genetics

Volumn 81, Issue 1, 2012, Pages 4-6

  Caulfield, T ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

DTC genetic testing; Ethics; Health policy; Regulatory policy

Indexed keywords

GENETIC RISK; GENETIC SCREENING; HUMAN; MARKETING; MEDICAL INFORMATION; NOTE; POLICY; PRIORITY JOURNAL;

ADVERTISING AS TOPIC; CONSUMER PARTICIPATION; GENETIC TESTING; HEALTH POLICY; HUMANS; MARKETING OF HEALTH SERVICES;

EID: 83355177995     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2011.01799.x     Document Type: Note

References (26)

1. McAuliffe K, McAuliffe S. Keeping up with the genetic revolution. The New York Times, 6 November 1983. Available at:. Accessed on October 31, 2011.
2. Genetics: the future is now. Time Magazine, 17 January 1994.
3. Manning J, Gertzen J. Health care on edge of DNA revolution. Milwaukee Journal Sentinel, 22 December 2002.
4. Genetics: lodestar of medicine's future. The Salt Lake Tribune, 26 December 1999.
5. Hall SS. Revolution postponed: why the Human Genome Project has been disappointing. Sci Am 2010: 303 (4): 60-67. Available at:. Accessed on October 31, 2011.
6. Taylor P. The human genome project, 10 years in: did they oversell the revolution? The Globe and Mail, 17 February 2011.
7. Pollock A. Awaiting the genome payoff. The New York Times, 14 June 2010.
8. Wade N. A decade later, genetic map yields few new cures. The New York Times, 12 June 2010.
9. Latham J. The failure of the genome. The Guardian, 17 April 2011.
10. Marshall E. Waiting for the revolution. Science 2011: 331: 526-529.
11. Hall WD, Mathews R, Morley KI. Being more realistic about the public health impact of genomic medicine. PLoS Med 2010: 7 (10): e1000347.
12. Evans JP, Meslin EM, Marteau TM, Caulfield T. Deflating the genomic bubble. Science 2011: 331: 861-862.
13. Green RC, Roberts JS, Cupples LA et al. Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med 2009: 361: 245-254.
14. Bloss CS, Schork NJ, Topol EJ. Effect of direct-to-consumer genome wide profiling to assess disease risk. N Engl J Med 2011: 364 (6): 524-534.
15. McBride CM, Wade CH, Kaphingst KA. Consumers' views of direct-to-consumer genetic information. Annu Rev Genomics Hum Genet 2010: 11: 427-446.
16. Marteau TM, French DP, Griffin SJ et al. Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours. Cochrane Database Syst Rev 2010: 10: CD007275.
17. Collins RE, Wright AJ, Marteau TM. Impact of communicating personalized genetic risk information on perceived control over the risk: a systematic review. Genet Med 2011: 13 (4): 273-277.
18. The Canadian College of Medical Geneticists Ethics and Policy Committee. The CCMG policy statement on DTC genetic testing, 2011.
19. Secretary's Advisory Committee on Genetics, Health and Society (SACGHS). Direct-to-consumer genetic testing, April 2010. Available at:. Accessed on October 31, 2011.
20. American Bar Association. Resolution 114. ABA urges direct access to diagnostic medical testing, 2011. Available at:.
21. Kutz G. Direct-to-consumer genetic tests: misleading test results are further complicated by deceptive marketing and other questionable practices. United States Government Accountability Office, 22 July 2010. Available at:. Accessed on October 31, 2011.
22. McGuire A, Diaz CM, Wang T, Hilsenbeck SG. Social networkers' attitudes toward direct-to-consumer personal genome testing. Am J Bioethics 2009: 9 (7): 3-10.
23. Einsiedel EF, Geransar R. Framing genetic risk: trust and credibility markers in online direct-to-consumer advertising for genetic testing. New Genet Soc 2009: 28 (4): 339-362.
24. Sample I. Genetics tests flawed and inaccurate, say Dutch scientists, investigation found they gave wildly different results and arrived at predictions that were no better than flipping a coin. The Guardian, 30 May 2011. Available at:. Accessed on October 31, 2011.
25. Caulfield T. Direct-to-consumer testing: if consumers aren't anxious, why are policymakers? Hum Genet 2011: 130: 23-25.
26. Murray ABV, Carson MJ, Morris CA, Beckwith J. Illusions of scientific legitimacy: misrepresented science in the direct-to-consumer genetic-testing marketplace. Trends Genet 2010: 26 (11): 459-461.