A novel peptide derived from human pancreatitis-associated protein inhibits inflammation in vivo and in vitro and blocks NF-kappa b signaling pathway

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Yang, Xiaolu ^a,b   Jin, Huiyi ^a,b   Liu, Kun ^a,b   Gu, Qing ^a,b   Xu, Xun ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shanghai Key Laboratory of Fundus Disease   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PANCREATITIS ASSOCIATED PROTEIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; LECTIN; LIPOPOLYSACCHARIDE; PANCREATITIS-ASSOCIATED PROTEIN; PEPTIDE; TUMOR ANTIGEN; TUMOR MARKER;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AQUEOUS HUMOR; ARTICLE; BIOASSAY; CELL ADHESION; CELL INFILTRATION; CELL STRAIN U937; CELL TYPE; CLINICAL FEATURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TOXICITY TESTING; UMBILICAL VEIN ENDOTHELIAL CELL; UVEITIS; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; GENETICS; INFLAMMATION; INTRAVITREAL DRUG ADMINISTRATION; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RETINA;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, NEOPLASM; AQUEOUS HUMOR; CHEMOKINE CCL2; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; INTRAVITREAL INJECTIONS; LECTINS, C-TYPE; LIPOPOLYSACCHARIDES; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PEPTIDES; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RETINA; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA; UVEITIS;

EID: 83355172991     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029155     Document Type: Article

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