Differential proteolysis of sigma regulators controls cell-surface signalling in Pseudomonas aeruginosa

Molecular Microbiology

Volumn 82, Issue 6, 2011, Pages 1444-1453

  Draper, Richard C ^a   Martin, Lois W ^a   Beare, Paul A ^a,b   Lamont, Iain L ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE; FERRICHROME; FIUR PROTEIN; FOXR PROTEIN; PYOVERDINE; REGULATOR PROTEIN; SIDEROPHORE; SIGMA FACTOR; SIGMA FACTOR FPVL; SIGMA FACTOR PVDS; SIGMA REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; GENE EXPRESSION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION;

BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; PROTEOLYSIS; PSEUDOMONAS AERUGINOSA; SIDEROPHORES; SIGMA FACTOR; SIGNAL TRANSDUCTION;

NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 83355162691     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2011.07901.x     Document Type: Article

References (38)

1. E envelope stress response. Curr Opin Microbiol 11: 535-540.
2. Beare, P.A., For, R.J., Martin, L.W., and Lamont, I.L. (2003) Siderophore-mediated cell signalling in Pseudomonas aeruginosa: divergent pathways regulate virulence factor production and siderophore receptor synthesis. Mol Microbiol 47: 195-207.
3. Braun, V., and Mahren, S. (2005) Transmembrane transcriptional control (surface signalling) of the Escherichia coli Fec type. FEMS Microbiol Rev 29: 673-684.
4. Braun, V., Mahren, S., and Sauter, A. (2005) Gene regulation by transmembrane signaling. Biometals 18: 507-517.
5. Campbell, E.A., Greenwell, R., Anthony, J.R., Wang, S., Lim, L., Das, K., etal. (2007) A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria. Mol Cell 27: 793-805.
6. Cezairliyan, B.O., and Sauer, R.T. (2009) Control of Pseudomonas aeruginosa AlgW protease cleavage of MucA by peptide signals and MucB. Mol Microbiol 72: 368-379.
7. Chen, G., and Zhang, X. (2010) New insights into S2P signaling cascades: regulation, variation, and conservation. Protein Sci 19: 2015-2030.
8. Cornelis, P., and Matthijs, S. (2002) Diversity of siderophore-mediated iron uptake systems in fluorescent pseudomonads: not only pyoverdines. Environ Microbiol 4: 787-798.
9. Damron, F.H., and Yu, H.D. (2011) Pseudomonas aeruginosa MucD regulates the alginate pathway through activation of MucA degradation via MucP proteolytic activity. J Bacteriol 193: 286-291.
10. Drechsel, H., and Winkelmann, G. (1997) Iron Chelation and siderophores. In Transition Metals in Microbial Metabolism. Winkelmann, G., and Carrano, C.J. (eds). Amsterdam: Harwood Academic, pp. 1-49.
11. Driscoll, J.A., Brody, S.L., and Kollef, M.H. (2007) The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infections. Drugs 67: 351-368.
12. Harlow, E., and Lane, D. (1999) Using Antibodies: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
13. Heinrich, J., and Wiegert, T. (2009) Regulated intramembrane proteolysis in the control of extracytoplasmic function sigma factors. Res Microbiol 160: 696-703.
14. Heinrich, J., Hein, K., and Wiegert, T. (2009) Two proteolytic modules are involved in regulated intramembrane proteolysis of Bacillus subtilis RsiW. Mol Microbiol 74: 1412-1426.
15. Hernan, R., Heuermann, K., and Brizzard, B. (2000) Multiple epitope tagging of expressed proteins for enhanced detection. Biotechniques 28: 789-793.
16. Hoang, T.T., Karkhoff-Schweizer, R.R., Kutchma, A.J., and Schweizer, H.P. (1998) A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212: 77-86.
17. James, H.E., Beare, P.A., Martin, L.W., and Lamont, I.L. (2005) Mutational analysis of a bifunctional ferrisiderophore receptor and signal-transducing protein from Pseudomonas aeruginosa. J Bacteriol 187: 4514-4520.
18. King, E.O., Ward, M.K., and Raney, D.E. (1954) Two simple media for the demonstration of pyocyanin and fluorescein. J Lab Med 44: 301-307.
19. King-Lyons, N.D., Smith, K.F., and Connell, T.D. (2007) Expression of hurP, a gene encoding a prospective site 2 protease, is essential for heme-dependent induction of bhuR in Bordetella bronchiseptica. J Bacteriol 189: 6266-6275.
20. Lamont, I.L., Beare, P.A., Ochsner, U., Vasil, A.I., and Vasil, M.L. (2002) Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa. Proc Natl Acad Sci USA 99: 7072-7077.
21. Llamas, M.A., Sparrius, M., Kloet, R., Jimenez, C.R., Vandenbroucke-Grauls, C., and Bitter, W. (2006) The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa. J Bacteriol 188: 1882-1891.
22. Mettrick, K.A., and Lamont, I.L. (2009) Different roles for anti-sigma factors in siderophore signalling pathways of Pseudomonas aeruginosa. Mol Microbiol 74: 1257-1271.
23. Michel, L., Gonzalez, N., Jagdeep, S., Nguyen-Ngoc, T., and Reimmann, C. (2005) PchR-box recognition by the AraC-type regulator PchR of Pseudomonas aeruginosa requires the siderophore pyochelin as an effector. Mol Microbiol 58: 495-509.
24. Noinaj, N., Guillier, M., Barnard, T.J., and Buchanan, S.K. (2010) TonB-dependent transporters: regulation, structure, and function. Annu Rev Microbiol 64: 43-60.
25. Palmer, K.L., Mashburn, L.M., Singh, P.K., and Whiteley, M. (2005) Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J Bacteriol 187: 5267-5277.
26. Poole, K., and McKay, G.A. (2003) Iron acquisition and its control in Pseudomonas aeruginosa: many roads lead to Rome. Front Biosci 8: d661-d686.
27. Qiu, D., Eisinger, V.M., Rowen, D.W., and Yu, H.D. (2007) Regulated proteolysis controls mucoid conversion in Pseudomonas aeruginosa. Proc Natl Acad Sci USA 104: 8107-8112.
28. Ratledge, C., and Dover, L.G. (2000) Iron metabolism in pathogenic bacteria. Annu Rev Microbiol 54: 881-941.
29. Reiling, S.A., Jansen, J.A., Henley, B.J., Singh, S., Chattin, C., Chandler, M., and Rowen, D.W. (2005) Prc protease promotes mucoidy in mucA mutants of Pseudomonas aeruginosa. Microbiology 151: 2251-2261.
30. Sambrook, J., Russell, D.W., and Irwin, N. (2000) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
31. Schalk, I.J., Lamont, I.L., and Cobessi, D. (2009) Structure-function relationships in the bifunctional ferrisiderophore FpvA receptor from Pseudomonas aeruginosa. Biometals 22: 671-678.
32. Shen, J., Meldrum, A., and Poole, K. (2002) FpvA receptor involvement in pyoverdine biosynthesis in Pseudomonas aeruginosa. J Bacteriol 184: 3268-3275.
33. Spencer, M.R., Beare, P.A., and Lamont, I.L. (2008) Role of cell surface signaling in proteolysis of an alternative sigma factor in Pseudomonas aeruginosa. J Bacteriol 190: 4865-4869.
34. Tiburzi, F., Imperi, F., and Visca, P. (2008) Intracellular levels and activity of PvdS, the major iron starvation sigma factor of Pseudomonas aeruginosa. Mol Microbiol 67: 213-227.
35. Urban, S. (2009) Making the cut: central roles of intramembrane proteolysis in pathogenic microorganisms. Nat Rev Microbiol 7: 411-423.
36. Visca, P., Leoni, L., Wilson, M.J., and Lamont, I.L. (2002) Iron transport and regulation, cell signalling and genomics: lessons from Escherichia coli and Pseudomonas. Mol Microbiol 45: 1177-1190.
37. 22 (AlgT/U) activation by regulated proteolysis and its regulon in Pseudomonas aeruginosa. Mol Microbiol 72: 183-201.
38. 22 (AlgT) and the AlgW and Prc proteases. Mol Microbiol 62: 412-426.