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Volumn 31, Issue 24, 2011, Pages 5037-5045

Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; MYC PROTEIN;

EID: 83255188972     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/mcb.06297-11     Document Type: Article
Times cited : (20)

References (44)
  • 1
    • 0033598354 scopus 로고    scopus 로고
    • p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis
    • Allan, L. A., and M. Fried. 1999. p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis. Oncogene 18:5403-5412.
    • (1999) Oncogene , vol.18 , pp. 5403-5412
    • Allan, L.A.1    Fried, M.2
  • 2
    • 0344009714 scopus 로고    scopus 로고
    • c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis
    • Arango, D., et al. 2003. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. Br. J. Cancer 89:1757-1765.
    • (2003) Br. J. Cancer , vol.89 , pp. 1757-1765
    • Arango, D.1
  • 3
    • 16844376909 scopus 로고    scopus 로고
    • Reverse engineering of regulatory networks in human B cells
    • Basso, K., et al. 2005. Reverse engineering of regulatory networks in human B cells. Nat. Genet. 37:382-390.
    • (2005) Nat. Genet. , vol.37 , pp. 382-390
    • Basso, K.1
  • 4
    • 33745050250 scopus 로고    scopus 로고
    • Estrogen receptor beta (ERbeta) protein expression correlates with BAG-1 and prognosis in brain glial tumours
    • Batistatou, A., et al. 2006. Estrogen receptor beta (ERbeta) protein expression correlates with BAG-1 and prognosis in brain glial tumours. J. Neurooncol. 77:17-23.
    • (2006) J. Neurooncol. , vol.77 , pp. 17-23
    • Batistatou, A.1
  • 5
    • 0035881691 scopus 로고    scopus 로고
    • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
    • Bouchard, C., et al. 2001. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev. 15:2042-2047.
    • (2001) Genes Dev. , vol.15 , pp. 2042-2047
    • Bouchard, C.1
  • 6
    • 0032535177 scopus 로고    scopus 로고
    • c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets
    • Bush, A., et al. 1998. c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets. Genes Dev. 12:3797-3802.
    • (1998) Genes Dev. , vol.12 , pp. 3797-3802
    • Bush, A.1
  • 7
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen, X., et al. 2008. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-1117.
    • (2008) Cell , vol.133 , pp. 1106-1117
    • Chen, X.1
  • 8
    • 41849140006 scopus 로고    scopus 로고
    • BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity
    • Clemo, N. K., et al. 2008. BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity. Carcinogenesis 29:849-857.
    • (2008) Carcinogenesis , vol.29 , pp. 849-857
    • Clemo, N.K.1
  • 9
    • 33748171960 scopus 로고    scopus 로고
    • The c-Myc target gene network
    • Dang, C. V., et al. 2006. The c-Myc target gene network. Semin. Cancer Biol. 16:253-264.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 253-264
    • Dang, C.V.1
  • 10
    • 0035126052 scopus 로고    scopus 로고
    • c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
    • D'Cruz, C. M., et al. 2001. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat. Med. 7:235-239.
    • (2001) Nat. Med. , vol.7 , pp. 235-239
    • D'Cruz, C.M.1
  • 11
    • 0024396222 scopus 로고
    • Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells
    • Eilers, M., D. Picard, K. R. Yamamoto, and J. M. Bishop. 1989. Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature 340:66-68.
    • (1989) Nature , vol.340 , pp. 66-68
    • Eilers, M.1    Picard, D.2    Yamamoto, K.R.3    Bishop, J.M.4
  • 12
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • Evan, G. I., et al. 1992. Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119-128.
    • (1992) Cell , vol.69 , pp. 119-128
    • Evan, G.I.1
  • 13
    • 0031281806 scopus 로고    scopus 로고
    • Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells
    • Fife, R. S., B. T. Rougraff, C. Proctor, and G. W. Sledge, Jr. 1997. Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells. J. Lab. Clin. Med. 130:530-534.
    • (1997) J. Lab. Clin. Med. , vol.130 , pp. 530-534
    • Fife, R.S.1    Rougraff, B.T.2    Proctor, C.3    Sledge Jr., G.W.4
  • 14
    • 0035881472 scopus 로고    scopus 로고
    • Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation
    • Frank, S. R., M. Schroeder, P. Fernandez, S. Taubert, and B. Amati. 2001. Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev. 15:2069-2082.
    • (2001) Genes Dev. , vol.15 , pp. 2069-2082
    • Frank, S.R.1    Schroeder, M.2    Fernandez, P.3    Taubert, S.4    Amati, B.5
  • 16
    • 63449137661 scopus 로고    scopus 로고
    • Multiple, but concerted cellular activities of the human protein Hap46/BAG-1M and isoforms
    • Gehring, U. 2009. Multiple, but concerted cellular activities of the human protein Hap46/BAG-1M and isoforms. Int. J. Mol. Sci. 10:906-928.
    • (2009) Int. J. Mol. Sci. , vol.10 , pp. 906-928
    • Gehring, U.1
  • 17
    • 13144292426 scopus 로고    scopus 로고
    • BAG-1 haplo-insufficiency impairs lung tumorigenesis
    • Gotz, R., B. W. Kramer, G. Camarero, and U. R. Rapp. 2004. BAG-1 haplo-insufficiency impairs lung tumorigenesis. BMC Cancer 4:85.
    • (2004) BMC Cancer , vol.4 , pp. 85
    • Gotz, R.1    Kramer, B.W.2    Camarero, G.3    Rapp, U.R.4
  • 18
    • 33745737494 scopus 로고    scopus 로고
    • Myc-binding-site recognition in the human genome is determined by chromatin context
    • Guccione, E., et al. 2006. Myc-binding-site recognition in the human genome is determined by chromatin context. Nat. Cell Biol. 8:764-770.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 764-770
    • Guccione, E.1
  • 19
    • 0036187113 scopus 로고    scopus 로고
    • A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology
    • Gunther, E. J., et al. 2002. A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. FASEB J. 16:283-292.
    • (2002) FASEB J. , vol.16 , pp. 283-292
    • Gunther, E.J.1
  • 20
    • 33744960411 scopus 로고    scopus 로고
    • A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling
    • Hummel, M., et al. 2006. A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. N. Engl. J. Med. 354:2419-2430.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2419-2430
    • Hummel, M.1
  • 21
    • 0021721180 scopus 로고
    • Regulation of heat shock protein 70 gene expression by c-myc
    • Kingston, R. E., A. S. Baldwin, Jr., and P. A. Sharp. 1984. Regulation of heat shock protein 70 gene expression by c-myc. Nature 312:280-282.
    • (1984) Nature , vol.312 , pp. 280-282
    • Kingston, R.E.1    Baldwin Jr., A.S.2    Sharp, P.A.3
  • 22
    • 51649089695 scopus 로고    scopus 로고
    • Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials
    • Klapper, W., et al. 2008. Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. Blood 112: 1374-1381.
    • (2008) Blood , vol.112 , pp. 1374-1381
    • Klapper, W.1
  • 23
    • 0037853196 scopus 로고    scopus 로고
    • Efficient production of human FVIII in hemophilic mice using lentiviral vectors
    • Kootstra, N. A., R. Matsumura, and I. M. Verma. 2003. Efficient production of human FVIII in hemophilic mice using lentiviral vectors. Mol. Ther. 7:623-631.
    • (2003) Mol. Ther. , vol.7 , pp. 623-631
    • Kootstra, N.A.1    Matsumura, R.2    Verma, I.M.3
  • 24
    • 33646718825 scopus 로고    scopus 로고
    • Expression of BAG-1 protein correlates with aggressive behavior of prostate cancers
    • Krajewska, M., B. C. Turner, A. Shabaik, S. Krajewski, and J. C. Reed. 2006. Expression of BAG-1 protein correlates with aggressive behavior of prostate cancers. Prostate 66:801-810.
    • (2006) Prostate , vol.66 , pp. 801-810
    • Krajewska, M.1    Turner, B.C.2    Shabaik, A.3    Krajewski, S.4    Reed, J.C.5
  • 25
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe, S. W., E. Cepero, and G. Evan. 2004. Intrinsic tumour suppression. Nature 432:307-315.
    • (2004) Nature , vol.432 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 26
    • 34547099086 scopus 로고    scopus 로고
    • Overexpression and gene amplification of BAG-1L in hormone-refractory prostate cancer
    • Maki, H. E., et al. 2007. Overexpression and gene amplification of BAG-1L in hormone-refractory prostate cancer. J. Pathol. 212:395-401.
    • (2007) J. Pathol. , vol.212 , pp. 395-401
    • Maki, H.E.1
  • 27
    • 0032493894 scopus 로고    scopus 로고
    • The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
    • McMahon, S. B., H. A. Van Buskirk, K. A. Dugan, T. D. Copeland, and M. D. Cole. 1998. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94:363-374.
    • (1998) Cell , vol.94 , pp. 363-374
    • McMahon, S.B.1    Van Buskirk, H.A.2    Dugan, K.A.3    Copeland, T.D.4    Cole, M.D.5
  • 28
    • 0033970431 scopus 로고    scopus 로고
    • The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc
    • McMahon, S. B., M. A. Wood, and M. D. Cole. 2000. The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. Mol. Cell. Biol. 20:556-562.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 556-562
    • McMahon, S.B.1    Wood, M.A.2    Cole, M.D.3
  • 29
    • 56849093474 scopus 로고    scopus 로고
    • Distinct thresholds govern Myc's biological output in vivo
    • Murphy, D. J., et al. 2008. Distinct thresholds govern Myc's biological output in vivo. Cancer Cell 14:447-457.
    • (2008) Cancer Cell , vol.14 , pp. 447-457
    • Murphy, D.J.1
  • 30
    • 0036211680 scopus 로고    scopus 로고
    • Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines
    • Park, Y. B., et al. 2002. Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines. Cancer Genet. Cytogenet. 133:105-111.
    • (2002) Cancer Genet. Cytogenet. , vol.133 , pp. 105-111
    • Park, Y.B.1
  • 32
    • 33846948993 scopus 로고    scopus 로고
    • BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis
    • Patel, J. H., and S. B. McMahon. 2007. BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis. J. Biol. Chem. 282: 5-13.
    • (2007) J. Biol. Chem. , vol.282 , pp. 5-13
    • Patel, J.H.1    McMahon, S.B.2
  • 33
    • 33645649406 scopus 로고    scopus 로고
    • Targeting of MIZ-1 is essential for MYC mediated apoptosis
    • Patel, J. H., and S. B. McMahon. 2006. Targeting of MIZ-1 is essential for MYC mediated apoptosis. J. Biol. Chem. 281:3283-3289.
    • (2006) J. Biol. Chem. , vol.281 , pp. 3283-3289
    • Patel, J.H.1    McMahon, S.B.2
  • 34
    • 34347401998 scopus 로고    scopus 로고
    • The ubiquitin-specific protease USP28 is required for MYC stability
    • Popov, N., et al. 2007. The ubiquitin-specific protease USP28 is required for MYC stability. Nat. Cell Biol. 9:765-774.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 765-774
    • Popov, N.1
  • 35
    • 33847246805 scopus 로고    scopus 로고
    • Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
    • Rhodes, D. R., et al. 2007. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia 9:166-180.
    • (2007) Neoplasia , vol.9 , pp. 166-180
    • Rhodes, D.R.1
  • 36
    • 0023136649 scopus 로고
    • Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity
    • Sarid, J., T. D. Halazonetis, W. Murphy, and P. Leder. 1987. Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity. Proc. Natl. Acad. Sci. U. S. A. 84:170-173.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 170-173
    • Sarid, J.1    Halazonetis, T.D.2    Murphy, W.3    Leder, P.4
  • 37
    • 70350445530 scopus 로고    scopus 로고
    • Thioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions
    • Sharp, A., et al. 2009. Thioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions. J. Pharmacol. Exp. Ther. 331:680-689.
    • (2009) J. Pharmacol. Exp. Ther. , vol.331 , pp. 680-689
    • Sharp, A.1
  • 38
    • 53349103292 scopus 로고    scopus 로고
    • Modelling Myc inhibition as a cancer therapy
    • Soucek, L., et al. 2008. Modelling Myc inhibition as a cancer therapy. Nature 455:679-683.
    • (2008) Nature , vol.455 , pp. 679-683
    • Soucek, L.1
  • 39
    • 0023116071 scopus 로고
    • Definition of regions in human c-myc that are involved in transformation and nuclear localization
    • Stone, J., et al. 1987. Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol. Cell. Biol. 7:1697-1709.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1697-1709
    • Stone, J.1
  • 40
    • 33845656738 scopus 로고    scopus 로고
    • Acetylation of the p53 DNA-binding domain regulates apoptosis induction
    • Sykes, S. M., et al. 2006. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Mol. Cell 24:841-851.
    • (2006) Mol. Cell , vol.24 , pp. 841-851
    • Sykes, S.M.1
  • 42
    • 0344121269 scopus 로고    scopus 로고
    • Antisense BAG-1 sensitizes HeLa cells to apoptosis by multiple pathways
    • Xiong, J., et al. 2003. Antisense BAG-1 sensitizes HeLa cells to apoptosis by multiple pathways. Biochem. Biophys. Res. Commun. 312:585-591.
    • (2003) Biochem. Biophys. Res. Commun. , vol.312 , pp. 585-591
    • Xiong, J.1
  • 43
    • 32244432921 scopus 로고    scopus 로고
    • Identification of novel targets of MYC whose transcription requires the essential MbII domain
    • Zhang, X. Y., L. M. Desalle, and S. B. McMahon. 2006. Identification of novel targets of MYC whose transcription requires the essential MbII domain. Cell Cycle 5:238-241.
    • (2006) Cell Cycle , vol.5 , pp. 238-241
    • Zhang, X.Y.1    Desalle, L.M.2    McMahon, S.B.3
  • 44
    • 25444508476 scopus 로고    scopus 로고
    • Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein
    • Zhang, X. Y., et al. 2005. Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein. Proc. Natl. Acad. Sci. U. S. A. 102:13968-13973.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 13968-13973
    • Zhang, X.Y.1


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