Profiling of Autoantibodies in IgA nephropathy, an integrative antibiomics approach

Clinical Journal of the American Society of Nephrology

Volumn 6, Issue 12, 2011, Pages 2775-2784

  Sigdel, Tara K ^a   Woo, Sang Hoon ^a   Dai, Hong ^a   Khatri, Purvesh ^a   Li, Li ^a   Myers, Bryan ^a   Sarwal, Minnie M ^a   Lafayette, Richard A ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DEAD BOX PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1; IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 3; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN MU CHAIN; MATRILINE 2; PROTEIN; PROTEIN KINASE D1; UBIQUITIN CONJUGATING ENZYME E2W; UNCLASSIFIED DRUG;

ADULT; ANTIBODY DETECTION; ARTICLE; BIOINFORMATICS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GLOMERULUS; GLOMERULUS FILTRATION RATE; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOPATHOGENESIS; KIDNEY TUBULE; MALE; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN URINE LEVEL;

ADULT; ANTIBODY SPECIFICITY; AUTOANTIBODIES; COMPUTATIONAL BIOLOGY; FEMALE; GLOMERULAR FILTRATION RATE; GLOMERULONEPHRITIS, IGA; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROTEIN KINASE C; UBIQUITIN-CONJUGATING ENZYMES;

EID: 83155193272     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.04600511     Document Type: Article

References (32)

1. Suzuki H, Fan R, Zhang Z, Brown R, Hall S, Julian BA, Chatham WW, Suzuki Y, Wyatt RJ, Moldoveanu Z, Lee JY, Robinson J, Tomana M, Tomino Y, Mestecky J, Novak J: Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity. J Clin Invest 119: 1668-1677, 2009
2. Berger J, Hinglais N: [Intercapillary deposits of IgA-IgG]. J Urol Nephrol (Paris) 74: 694-695, 1968
3. Ibels LS, Gyory AZ: IgA nephropathy: Analysis of the natural history, important factors in the progression of renal disease, and a review of the literature. Medicine (Baltimore) 73: 79-102, 1994
4. Schnack C, Hengerer B, Gillardon F: Identification of novel substrates for Cdk5 and new targets for Cdk5 inhibitors using high-density protein microarrays. Proteomics 8: 1980-1986, 2008
5. Li L, Wadia P, Chen R, Kambham N, Naesens M, Sigdel TK, Miklos DB, Sarwal MM, Butte AJ: Identifying compartmentspecific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures. Proc Natl Acad Sci U S A 106: 4148-4153, 2009
6. Meng L, Michaud GA, Merkel JS, Zhou F, Huang J, Mattoon DR, Schweitzer B: Protein kinase substrate identification on functional protein arrays. BMC Biotechnol 8: 22, 2008
7. Squarer A, Lemley KV, Ambalavanan S, Kristal B, Deen WM, Sibley R, Anderson L, Myers BD: Mechanisms of progressive glomerular injury in membranous nephropathy. J Am Soc Nephrol 9: 1389-1398, 1998
8. Sigdel T, Kaushal A, Gritsenko M, Norbeck A, Qian W, Xiao W, Camp D, Smith R, Sarwal M: Novel shotgun proteomics approach identifies proteins specific for acute renal transplant rejection. Am J Transplant 10: 289-290, 2010
9. Sutherland SM, Li L, Sigdel TK, Wadia PP, Miklos DB, Butte AJ, Sarwal MM: Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipients. Kidney Int 76: 1277-1283, 2009
10. Sboner A, Karpikov A, Chen G, Smith M, Mattoon D, Freeman-Cook L, Schweitzer B, Gerstein MB: Robust-linearmodel normalization to reduce technical variability in functional protein microarrays. J Proteome Res 8: 5451-5464, 2009
11. Hiromura K, Pippin JW, Fero ML, Roberts JM, Shankland SJ: Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1). J Clin Invest 103: 597-604, 1999
12. Moreno-Manzano V, Ishikawa Y, Lucio-Cazana J, Kitamura M: Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells. J Biol Chem 275: 12684-12691, 2000
13. Juang YT, Wang Y, Solomou EE, Li Y, Mawrin C, Tenbrock K, Kyttaris VC, Tsokos GC: Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV. J Clin Invest 115: 996-1005, 2005
14. Brambila-Tapia AJ, Gamez-Nava JI, Gonzalez-Lopez L, Sandoval-Ramirez L, Medina-Diaz J, Maldonado M, Gutierrez-Urena SR, Martinez-Bonilla G, Martin-Marquez BT, Vazquez Del Mercado M, Nava-Zavala A, Munoz-Valle JF, Salazar-Paramo M, Davalos-Rodriguez, IP: FCGR3A V(176) polymorphism for systemic lupus erythematosus susceptibility in Mexican population. Rheumatol Int 31: 1065-1068, 2011
15. Li Y, Chen F, Putt M, Koo YK, Madaio M, Cambier JC, Cohen PL, Eisenberg RA: B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice. J Immunol 181: 2961-2972, 2008
16. Chechlinska M, Siwicki JK, Gos M, Oczko-Wojciechowska M, Jarzab M, Pfeifer A, Jarzab B, Steffen J: Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal. BMC Genomics 10: 261, 2009
17. Berglund L, Bjorling E, Oksvold P, Fagerberg L, Asplund A, Szigyarto CA, Persson A, Ottosson J, Wernerus H, Nilsson P, Lundberg E, Sivertsson A, Navani S, Wester K, Kampf C, Hober S, Ponten F, Uhlen M: A genecentric Human Protein Atlas for expression profiles based on antibodies. Mol Cell Proteomics 7: 2019-2027, 2008
18. Shan J, Wang P, Zhou J, Wu D, Shi H, Huo K: RIOK3 interacts with caspase-10 and negatively regulates the NF-kappaB signaling pathway. Mol Cell Biochem 332: 113-120, 2009
19. Higgins JP, Wang L, Kambham N, Montgomery K, Mason V, Vogelmann SU, Lemley KV, Brown PO, Brooks JD, van de Rijn M: Gene expression in the normal adult human kidney assessed by complementary DNA microarray. Mol Biol Cell 15: 649-656, 2004
20. Smith AC, Molyneux K, Feehally J, Barratt J: O-glycosylation of serum IgA1 antibodies against mucosal and systemic antigens in IgA nephropathy. J Am Soc Nephrol 17: 3520-3528, 2006
21. Jones CL, Powell HR, Kincaid-Smith P, Roberton DM: Polymeric IgA and immune complex concentrations in IgA-related renal disease. Kidney Int 38: 323-331, 1990
22. Reterink TJ, Schroeijers WE, Es LA, Daha MR: Dimeric and polymeric IgA, but not monomeric IgA, enhance the production of IL-6 by human renal mesangial cells. Mediators Inflamm 5: 191-195, 1996
23. Piecha D, Muratoglu S, Morgelin M, Hauser N, Studer D, Kiss I, Paulsson M, Deak F: Matrilin-2, a large, oligomeric matrix protein, is expressed by a great variety of cells and forms fibrillar networks. J Biol Chem 274: 13353-13361, 1999
24. Cordin O, Banroques J, Tanner NK, Linder P: The DEAD-box protein family of RNA helicases. Gene 367: 17-37, 2006
25. Nandi D, Tahiliani P, Kumar A, Chandu D: The ubiquitinproteasome system. J Biosci 31: 137-155, 2006
26. Bergmann J, Buchheidt D, Waldherr R, Maywald O, van der Woude FJ, Hehlmann R, Braun C: IgA nephropathy and hodgkin's disease: A rare coincidence. Case report and literature review. Am J Kidney Dis 45: e16-e19, 2005
27. Mak SK, Wong PN, Lo KY, Wong AK: Successful treatment of IgA nephropathy in association with low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue type. Am J Kidney Dis 31: 713-718, 1998
28. Hubert D, Beaufils M, Meyrier A: [Immunoglobulin A glomerular nephropathy associated with inflammatory colitis. Apropos of 2 cases]. Presse Med 13: 1083-1085, 1984
29. Dux S, Grosskopf I, Rosenfeld JB: Recurrent erythema nodosum, arthritis and IgA nephropathy. Dermatologica 176: 293-295, 1988
30. Weiner NJ, Goodman JW, Kimmel PL: The HIV-associated renal diseases: Current insight into pathogenesis and treatment. Kidney Int 63: 1618-1631, 2003
31. Corrado A, Quarta L, Di Palma AM, Gesualdo L, Cantatore FP: IgA nephropathy in systemic lupus erythematosus. Clin Exp Rheumatol 25: 467-469, 2007
32. Takemura T, Okada M, Yagi K, Kuwajima H, Yanagida H: An adolescent with IgA nephropathy and Crohn disease: Pathogenetic implications. Pediatr Nephrol 17: 863-866, 2002