Vitamin D intoxication with severe hypercalcemia due to manufacturing and labeling errors of two dietary supplements made in the United States

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 12, 2011, Pages 3603-3608

  Araki, Takako ^a   Holick, Michael F ^b   Alfonso, Bianca D ^a   Charlap, Esti ^a   Romero, Carla M ^a   Rizk, Dahlia ^a   Newman, Lisa G ^a,c  

^a BETH ISRAEL MEDICAL CENTER   (United States)

^b BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCITONIN; CALCITRIOL; CALCIUM; COLECALCIFEROL; FUROSEMIDE; PAMIDRONIC ACID; SODIUM CHLORIDE;

ADULT; CASE REPORT; CONFERENCE PAPER; DIET SUPPLEMENTATION; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; DRUG LABELING; DRUG MANUFACTURE; DRUG OVERDOSE; ERROR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDRATION; HYPERCALCEMIA; LABORATORY TEST; MALE; PRIORITY JOURNAL; ULTRAVIOLET SPECTROPHOTOMETRY; UNITED STATES; VITAMIN BLOOD LEVEL; VITAMIN D INTOXICATION;

ADULT; DIETARY SUPPLEMENTS; DRUG LABELING; HUMANS; HYPERCALCEMIA; MALE; MIDDLE AGED; VITAMIN D;

EID: 83155192292     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-1443     Document Type: Conference Paper

References (26)

1. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST 2008 Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA 300:2867-2878
2. Radimer K, Bindewald B, Hughes J, Ervin B, Swanson C, Picciano MF 2004 Dietary supplement use by US adults: data from the National Health and Nutrition Examination Survey, 1999-2000.AmJ Epidemiol 160:339-349 (Pubitemid 39045265)
3. Gardiner P, Graham RE, Legedza AT, Eisenberg DM, Phillips RS 2006 Factors associated with dietary supplement use among prescription medication users. Arch Intern Med 166:1968-1974 (Pubitemid 44537176)
4. Rock CL 2007 Multivitamin-multimineral supplements: who uses them? Am J Clin Nutr 85:277S-279S (Pubitemid 46067648)
5. Chen TC, Turner AK, Holick MF 1990 A method for the determination of the circulating concentration of vitamin D. J Nutr Biochem 1:272-276 (Pubitemid 20199387)
6. Down PF, Polak A, Regan RJ 1979 A family with massive acute vitamin D intoxication. Postgrad Med J 55:897-902 (Pubitemid 10202825)
7. Jacobus CH, Holick MF, Shao Q, Chen TC, Holm IA, Kolodny JM, Fuleihan GE, Seely EW 1992 Hypervitaminosis D associated with drinking milk. N Engl J Med 326:1173-1177
8. Kaptein S, Risselada AJ, Boerma EC, Egbers PH, Nieboer P 2010 Life-threatening complications of vitamin D intoxication due to over-the-counter supplements. Clin Toxicol (Phila) 48:460-462
9. Klontz KC, Acheson DW 2007 Dietary supplement-induced vitamin D intoxication. N Engl J Med 357:308-309
10. Koutkia P, Chen TC, Holick MF 2001 Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 345: 66-67 (Pubitemid 32634279)
11. Leu JP, Weiner A, Barzel US 2008 Vitamin D toxicity: caveat emptor. Endocr Pract 14:1188-1190
12. Lowe H, Cusano NE, Binkley N, Blaner WS, Bilezikian JP 2011 Vitamin D toxicity due to a commonly available "over the counter"remedy from the Dominican Republic. J Clin Endocrinol Metab 96:291-295
13. Vieth R, Pinto TR, Reen BS, Wong MM 2002 Vitamin D poisoning by table sugar. Lancet 359:672 (Pubitemid 34203768)
14. 2008 The evolving natural lifestyle: SPINS natural products market review. Series of reports. Chicago: Mintel International Group Ltd.
15. Forrest KY, Stuhldreher WL 2011 Prevalence and correlates of vitamin D deficiency in US adults. Nutr Res 31:48-54
16. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM 2011 Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 96:1911-1930
17. Ross AC 2011 The 2011 report on dietary reference intakes for calcium and vitamin D. Public Health Nutr 14:938-939
18. Jacobs TP, Bilezikian JP 2005 Clinical review: rare causes of hypercalcemia. J Clin Endocrinol Metab 90:6316-6322 (Pubitemid 41606563)
19. Vieth R 1999 Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr 69:842-856 (Pubitemid 29205056)
20. Khanna A 2006 Acquired nephrogenic diabetes insipidus. Semin Nephrol 26:244-248
21. Propp S, Scharfman WB 1956 Anemia associated with vitamin D intoxication. N Engl J Med 255:1207-1212
22. Levi M, Ellis MA, Berl T 1983 Control of renal hemodynamics and glomerular filtration rate in chronic hypercalcemia. Role of prostaglandins, renin-angiotensin system, and calcium. J Clin Invest 71: 1624-1632 (Pubitemid 13056767)
23. Deluca HF, Prahl JM, Plum LA 2011 1,25-Dihydroxyvitamin D is not responsible for toxicity caused by vitamin D or 25-hydroxyvitamin D. Arch Biochem Biophys 505:226-230
24. Selby PL, Davies M, Marks JS, Mawer EB 1995 Vitamin D intoxication causes hypercalcaemia by increased bone resorption which responds to pamidronate. Clin Endocrinol (Oxf) 43:531-536
25. Ashar BH, Rice TN, Sisson SD 2007 Physicians' understanding of the regulation of dietary supplements. Arch Intern Med 167:966-969 (Pubitemid 46762760)
26. Gardiner P, Sarma DN, Low Dog T, Barrett ML, Chavez ML, Ko R, Mahady GB, Marles RJ, Pellicore LS, Giancaspro GI 2008 The state of dietary supplement adverse event reporting in the United States. Pharmacoepidemiol Drug Saf 17:962-970