Intracranial transplantation of monocyte-derived multipotential cells enhances recovery after ischemic stroke in rats

Journal of Neuroscience Research

Volumn 90, Issue 2, 2012, Pages 479-488

  Hattori, Hidenori ^a   Suzuki, Shigeaki ^a   Okazaki, Yuka ^a   Suzuki, Norihiro ^a   Kuwana, Masataka ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Macrophages; Monocytes; Stroke; Transplantation

Indexed keywords

ANGIOGENIC FACTOR; ANGIOPOIETIN 1; BIOLOGICAL MARKER; CD31 ANTIGEN; PLACENTAL GROWTH FACTOR; PROTEIN RECA 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD VESSEL; BRAIN ISCHEMIA; CELL DIFFERENTIATION; CELL LINEAGE; CELL TRANSPLANTATION; CONTROLLED STUDY; CONVALESCENCE; ENDOTHELIUM CELL; HISTOLOGY; MACROPHAGE; MALE; MESENCHYME CELL; MIDDLE CEREBRAL ARTERY OCCLUSION; MONOCYTE; MONOCYTE DERIVED MULTIPOTENTIAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME;

ANIMALS; BRAIN ISCHEMIA; CELLS, CULTURED; INJECTIONS, INTRAVENTRICULAR; MALE; MONOCYTES; MULTIPOTENT STEM CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; STEM CELL TRANSPLANTATION; STROKE;

EID: 83155175087     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22755     Document Type: Article

References (32)

1. Bang OY, Lee JS, Lee PH, Lee G. 2005. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 57: 874-882.
2. Belayev L, Alonso OF, Busto R, Zhao W, Ginsberg MD. 1996. Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 27: 1616-1622.
3. Brenneman M, Sharma S, Harting M, Strong R, Cox CSJr, Aronowski J, Grotta JC, Savitz SI. 2010. Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab 30: 140-149.
4. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M. 2001a. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 32: 1005-1011.
5. Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, Sanchez-Ramos J, Chopp M. 2001b. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 32: 2682-2688.
6. Fan Y, Shen F, Frenzel T, Zhu W, Ye J, Liu J, Chen Y, Su H, Young WL, Yang GY. 2010. Endothelial progenitor cell transplantation improves long-term stroke outcome in mice. Ann Neurol 67: 488-497.
7. Fischer UM, Harting MT, Jimenez F, Monzon-Posadas WO, Xue H, Savitz SI, Laine GA, Cox CS. 2008. Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first pass effect. Stem Cells Dev 18: 683-692.
8. Hermann DM, Zechariah A. 2009. Implications of vascular endothelial growth factor for postischemic neurovascular remodeling. J Cereb Blood Flow Metab 29: 1620-1643.
9. Ii M, Nishimura H, Sekiguchi H, Kamei N, Yokoyama A, Horii M, Asahara T. 2009. Concurrent vasculogenesis and neurogenesis from adult neural stem cells. Circ Res 105: 860-868.
10. Iihoshi S, Honmou O, Houkin K, Hashi K, Kocsis JD. 2004. A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats. Brain Res 1007: 1-9.
11. Ikawa M, Yamada S, Nakanishi T, Okabe M. 1999. Green fluorescent protein (GFP) as a vital marker in mammals. Curr Top Dev Biol 44: 1-20.
12. Johanson C, Stopa E, Baird A, Sharma H. 2011. Traumatic brain injury and recovery mechanisms: peptide modulation of periventricular neurogenic regions by the choroid plexus-CSF nexus. J Neural Transm 118: 115-133.
13. Kamiya N, Ueda M, Igarashi H, Nishiyama Y, Suda S, Inaba T, Katayama Y. 2008. Intra-arterial transplantation of bone marrow mononuclear cells immediately after reperfusion decreases brain injury after focal ischemia in rats. Life Sci 83: 433-437.
14. Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O. 2006. Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats. Stroke 37: 2361-2367.
15. + monocytes. Stem Cells Dev 14: 676-686.
16. + monocytes. Immunol Cell Biol 84: 209-217.
17. + monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. J Leukoc Biol 74: 833-845.
18. Kuwana M, Okazaki Y, Kodama H, Satoh T, Kawakami Y, Ikeda Y. 2006. Endothelial differentiation potential of human monocyte-derived multipotential cells. Stem Cells 24: 2733-2743.
19. Liu H, Honmou O, Harada K, Nakamura K, Houkin K, Hamada H, Kocsis JD. 2006. Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia. Brain 129: 2734-2745.
20. Onda T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. 2008. Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia. J Cereb Blood Flow Metab 28: 329-340.
21. Paxinos G, Watson C. 1998. The rat brain in stereotaxic coordinates, 4th ed. New York: Academic Press.
22. Rodrigues DM, Li AY, Nair DG, Blennerhassett MG. 2011. Glial cell line-derived neurotrophic factor is a key neurotrophin in the postnatal enteric nervous system. Neurogastroenterol Motil 23: e44-e56.
23. + monocytes. Exp Hematol 38: 557-563.
24. Shen LH, Li Y, Chen J, Cui Y, Zhang C, Kapke A, Lu M, Savant-Bhonsale S, Chopp M. 2007a. One-year follow-up after bone marrow stromal cell treatment in middle-aged female rats with stroke. Stroke 38: 2150-2156.
25. Shen LH, Li Y, Chen J, Zacharek A, Gao Q, Kapke A, Lu M, Raginski K, Vanguri P, Smith A, Chopp M. 2007b. Therapeutic benefit of bone marrow stromal cells administered 1 month after stroke. J Cereb Blood Flow Metab 27: 6-13.
26. Shyu WC, Lin SZ, Chiang MF, Su CY, Li H. 2006. Intracerebral peripheral blood stem cell (CD34) implantation induces neuroplasticity by enhancing β1 integrin-mediated angiogenesis in chronic stroke rats. J Neurosci 26: 3444-3453.
27. Suzuki S, Yamashita T, Tanaka K, Hattori H, Sawamoto K, Okano H, Suzuki N. 2005. Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. J Cereb Blood Flow Metab 25: 685-693.
28. Torry RJ, Tomanek RJ, Zheng W, Miller SJ, Labarrere CA, Torry DS. 2009. Hypoxia increases placenta growth factor expression in human myocardium and cultured neonatal rat cardiomyocytes. J Heart Lung Transplant 2: 183-190.
29. Yamamoto A, Takahashi H, Kojima Y, Tsuda Y, Morio Y, Muramatsu M, Fukuchi Y. 2007. Downregulation of angiopoietin-1 and Tie2 in chronic hypoxic pulmonary hypertension. Respiration 75: 328-338.
30. Zhang L, Schallert T, Zhang ZG, Jiang Q, Arniego P, Li Q, Lu M, Chopp M. 2002. A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia. J Neurosci Methods 117: 207-214.
31. Zhang ZG, Zhang L, Jiang Q, Chopp M. 2002. Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse. Circ Res 90: 284-288.
32. Zhao T, Li Y, Tang L, Li Y, Fan F, Jiang B. 2011. Protective effects of human umbilical cord blood stem cell intravitreal transplantation against optic nerve injury in rats. Graefes Arch Clin Exp Ophthalmol [E-pub ahead of print