Critically ill children during the 2009-2010 influenza pandemic in the United States

Pediatrics

Volumn 128, Issue 6, 2011, Pages

  Randolph, Adrienne G ^a,b   Vaughn, Frances ^c   Sullivan, Ryan ^a   Rubinson, Lewis ^c   Thompson, B Taylor ^d   Yoon, Grace ^a   Smoot, Elizabeth ^d   Rice, Todd W ^e   Loftis, Laura L ^f   Helfaer, Mark ^g   Doctor, Allan ^h   Paden, Matthew ⁱ   Flori, Heidi ^j   Babbitt, Christopher ^k   Graciano, Ana Lia ^l   Gedeit, Rainer ^m   Sanders, Ronald C ⁿ   Giuliano, John S ^o   Zimmerman, Jerry ^p   Uyeki, Timothy M ^q  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f TEXAS CHILDREN S HOSPITAL   (United States)

^g CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^h ST LOUIS CHILDREN S HOSPITAL   (United States)

ⁱ Children's Healthcare of Atlanta at Egleston ^*  (United States)

^j CHILDREN S HOSPITAL OAKLAND   (United States)

^k MILLER CHILDREN S HOSPITAL   (United States)

^l CHILDREN S HOSPITAL CENTRAL CALIFORNIA   (United States)

^m Children's Hospital of Wisconsin   (United States)

ⁿ ARKANSAS CHILDREN S HOSPITAL   (United States)

^o Yale Children's Hospital   (United States)

^p SEATTLE CHILDREN S HOSPITAL   (United States)

^q CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

more..

Author keywords

Influenza; Intensive care unit; Mortality; MRSA; Pandemic; Pediatric

Indexed keywords

AMANTADINE; CORTICOSTEROID; FRESH FROZEN PLASMA; HYPERTENSIVE FACTOR; IMMUNOGLOBULIN; OSELTAMIVIR; PERAMIVIR; RIBAVIRIN; RIMANTADINE; ZANAMIVIR;

2009 H1N1 INFLUENZA; ADOLESCENT; ADULT; ARTICLE; ARTIFICIAL VENTILATION; CHILD; CHILDHOOD MORTALITY; CHRONIC DISEASE; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DEMOGRAPHY; DISEASE COURSE; DRUG MEGADOSE; ENCEPHALITIS; FEMALE; GENDER; HEALTH STATUS; HUMAN; IMMUNE DEFICIENCY; INFANT; INTENSIVE CARE UNIT; LABORATORY TEST; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MIXED INFECTION; MYOCARDITIS; NEUROLOGIC DISEASE; OBSERVATIONAL STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY FAILURE; RETROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD; STAPHYLOCOCCUS INFECTION; UNITED STATES;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CRITICAL ILLNESS; FEMALE; HUMANS; INFANT; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; PANDEMICS; RETROSPECTIVE STUDIES; UNITED STATES; YOUNG ADULT;

EID: 83155173349     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2011-0774     Document Type: Article

References (53)

1. Presanis AM, De AD, Hagy A, et al. The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysis. PLoS Med. 2009;6(12):e1000207
2. Calatayud L, Kurkela S, Neave PE, et al. Pandemic (H1N1) 2009 virus outbreak in a school in London, April-May 2009: an observational study. Epidemiol Infect. 2010;138(2):183-191
3. Lessler J, Reich NG, Cummings DA, Nair HP, Jordan HT, Thompson N. Outbreak of 2009 pandemic influenza A (H1N1) at a New York City school. N Engl J Med. 2009;361(27):2628-2636
4. Shimada T, Gu Y, Kamiya H, et al. Epidemiology of influenza A(H1N1)v virus infection in Japan, May-June 2009. Euro Surveill. 2009;14(24):pii, 19244
5. Miller E, Hoschler K, Hardelid P, Stanford E, Andrews N, Zambon M. Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study. Lancet. 2010;375(9720):1100-1108
6. Reed C, Angulo FJ, Swerdlow DL, et al. Estimates of the prevalence of pandemic (H1N1) 2009, United States, April-July 2009. Emerg Infect Dis. 2009;15(12):2004-2007
7. Hackett S, Hill L, Patel J, et al. Clinical characteristics of paediatric H1N1 admissions in Birmingham, UK. Lancet. 2009;374(9690):605
8. Jain S, Kamimoto L, Bramley AM, et al. Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med. 2009;361(20):1935-1944
9. Larcombe PJ, Moloney SE, Schmidt PA. Pandemic (H1N1) 2009: a clinical spectrum in the general paediatric population. Arch Dis Child. 2011;96(1):96-98
10. Libster R, Bugna J, Coviello S, et al. Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina. N Engl J Med. 2010;362(1):45-55
11. Louie JK, Acosta M, Winter K, et al. Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California. JAMA. 2009;302(17):1896-1902
12. Centers for Disease Control and Prevention. Surveillance for pediatric deaths associated with 2009 pandemic influenza A (H1N1) virus infection: United States, April-August 2009. MMWR Morb Mortal Wkly Rep. 2009;58(34):941-947
13. Farias JA, Fernández A, Monteverde E, et al. Critically ill infants and children with influenza A (H1N1) in pediatric intensive care units in Argentina. Intensive Care Med. 2010;36(6):1015-1022
14. Jouvet P, Hutchison J, Pinto R, et al.; Canadian Critical Care Trials Group H1N1 Collaborative. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med. 2010;11(5):603-609
15. Lister P, Reynolds F, Parslow R, et al. Swineorigin influenza virus H1N1, seasonal influenza virus, and critical illness in children. Lancet. 2009;374(9690):605-607
16. Lockman JL, Fischer WA, Perl TM, Valsamakis A, Nichols DG. The critically ill child with novel H1N1 influenza A: a case series. Pediatr Crit Care Med. 2010;11(2):173-178
17. Sachedina N, Donaldson LJ. Paediatric mortality related to pandemic influenza A H1N1 infection in England: an observational population-based study. Lancet. 2010;376(9755):1846-1852
18. Cox CM, Blanton L, Dhara R, Brammer L, Finelli L. 2009 Pandemic influenza A (H1N1) deaths among children: United States, 2009-2010. Clin Infect Dis. 2011;52(suppl 1):S69-S74
19. Yung M, Slater A, Festa M, et al. Australia and New Zealand Intensive Care Influenza Investigators and the Paediatric Study Group and the Clinical Trials Group of the Australia New Zealand Intensive Care Society. Pandemic H1N1 in children requiring intensive care in Australia and New Zealand during winter 2009. Pediatrics. 2011;127(1). Available at: www.pediatrics.org/cgi/content/ full/127/1/e156
20. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap): a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377-381
21. Pollack MM, Patel KM, Ruttimann UE. PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med. 1996;24(5):743-752 (Pubitemid 26155716)
22. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13(10):818-829 (Pubitemid 15250137)
23. Hageman JC, Uyeki TM, Francis JS, et al. Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season. Emerg Infect Dis. 2006;12(6):894-899 (Pubitemid 43848409)
24. Bhat N, Wright JG, Broder KR, et al. Influenza Special Investigations Team. Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med. 2005;353(24):2559-2567 (Pubitemid 41785893)
25. Dawood FS, Fiore A, Kamimoto L, et al. Emerging Infections Program (EIP) Network. Influenza-associated pneumonia in children hospitalized with laboratory-confirmed influenza, 2003-2008. Pediatr Infect Dis J. 2010;29(7):585-590
26. Finelli L, Fiore A, Dhara R, et al. Influenza-associated pediatric mortality in the United States: increase of Staphylococcus aureus coinfection. Pediatrics. 2008;122(4):805-811
27. Kallen AJ, Reed C, Patton M, Arnold KE, Finelli L, Hageman J. Staphylococcus aureus community-onset pneumonia in patients admitted to children's hospitals during autumn and winter of 2006-2007. Epidemiol Infect. 2010;138(5):666-672
28. Murray RJ, Robinson JO, White JN, et al. Community-acquired pneumonia due to pandemic A(H1N1)2009 influenzavirus and methicillin resistant Staphylococcus aureus co-infection. PLoS ONE. 2010;5(1):e8705
29. Reed C, Kallen AJ, Patton M, et al. Infection with community-onset Staphylococcus aureus and influenza virus in hospitalized children. Pediatr Infect Dis J. 2009;28(7):572-576
30. Shieh WJ, Blau DM, Denison AM, et al. 2009 pandemic influenza A (H1N1): pathology and pathogenesis of 100 fatal cases in the United States. Am J Pathol. 2010;177(1):166-175
31. Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America; American Thoracic Society. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis. 2007;44(suppl 2):S27-S72 (Pubitemid 46290553)
32. Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, Kaplan SL, Karchmer AW, Levine DP, Murray BE, J Rybak M, Talan DA, Chambers HF; Infectious Diseases Society of America. HYPERLINK http://www.ncbi.nlm.nih.gov/pubmed/ 21208910. Clinical Practice Guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis. 2011 Feb 1;52(3):e18-55. Epub 2011 Jan 4. Erratum in: Clin Infect Dis. 2011 Aug 1;53(3):319
33. Bettinger JA, Sauve LJ, Scheifele DW, et al. Pandemic influenza in Canadian children: a summary of hospitalized pediatric cases. Vaccine. 2010;28(18):3180-3184
34. Shin SY, Kim JH, Kim HS, et al. Clinical characteristics of Korean pediatric patients critically ill with influenza A (H1N1) virus. Pediatr Pulmonol. 2010;45(10):1014-1020
35. Siston AM, Rasmussen SA, Honein MA, et al.; Pandemic H1N1 Influenza in Pregnancy Working Group. Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States. JAMA. 2010;303(15):1517-1525
36. Keren R, Zaoutis TE, Bridges CB, et al. Neurological and neuromuscular disease as a risk factor for respiratory failure in children hospitalized with influenza infection. JAMA. 2005;294(17):2188-2194 (Pubitemid 41571136)
37. Baltagi SA, Shoykhet M, Felmet K, Kochanek PM, Bell MJ. Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic. Pediatr Crit Care Med. 2010;11(2):179-184
38. Davis LE. Neurologic and muscular complications of the 2009 influenza A (H1N1) pandemic. Curr Neurol Neurosci Rep. 2010;10(6):476-483
39. Ekstrand JJ, Herbener A, Rawlings J, et al. Heightened neurologic complications in children with pandemic H1N1 influenza. Ann Neurol. 2010;68(5):762-766
40. Lyon JB, Remigio C, Milligan T, Deline C. Acute necrotizing encephalopathy in a child with H1N1 influenza infection. Pediatr Radiol. 2010;40(2):200-205
41. Guarner J, Paddock CD, Shieh WJ, et al. Histopathologic and immunohistochemical features of fatal influenza virus infection in children during the 2003-2004 season. Clin Infect Dis. 2006;43(2):132-140
42. Baruteau AE, Boimond N, Ramful D. Myocarditis associated with 2009 influenza A (H1N1) virus in children. Cardiol Young. 2010;20(3):351-352
43. Haessler S, Paez A, Rothberg M, Higgins T. 2009 pandemic H1N1-associated myocarditis in a previously healthy adult. Clin Microbiol Infect. 2011;17(4):572-574
44. Bratincsák A, El-Said HG, Bradley JS, Shayan K, Grossfeld PD, Cannavino CR. Fulminant myocarditis associated with pandemic H1N1 influenza A virus in children. J Am Coll Cardiol. 2010;55(9):928-929
45. Webb SA, Pettila V, Seppelt I, et al. Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med. 2009;361(20):1925- 1934
46. Davies A, Jones D, Bailey M, et al. Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome. JAMA. 2009;302(17):1888-1895
47. Domínguez-Cherit G, Lapinsky SE, Macias AE, et al. Critically ill patients with 2009 influenza A(H1N1) in Mexico. JAMA. 2009;302(17):1880-1887
48. Yu H, Liao Q, Yuan Y, et al. Effectiveness of oseltamivir on disease progression and viral RNA shedding in patients with mild pandemic 2009 influenza A H1N1: opportunistic retrospective study of medical charts in China. BMJ. 2010;341:c4779
49. Centers for Disease Control and Prevention. Update: influenza activity - United States, 2009-10 season. MMWR Morb Mortal Wkly Rep. 2010;59(29):901-908
50. Uyeki T. Diagnostic testing for 2009 pandemic influenza A (H1N1) virus infection in hospitalized patients. N Engl J Med. 2009;361(25):e114
51. Ampofo K, Herbener A, Blaschke AJ, et al. Association of 2009 pandemic influenza A (H1N1) infection and increased hospitalization with parapneumonic empyema in children in Utah. Pediatr Infect Dis J. 2010;29(10):905-909
52. Estenssoro E, Ríos FG, Apezteguía C, et al. Registry of the Argentinian Society of Intensive Care SATI. Pandemic 2009 influenza A in Argentina: a study of 337 patients on mechanical ventilation. Am J Respir Crit Care Med. 2010;182(1):41-48
53. Custer JW, Rau RE. Harriett Lane Handbook: A Manual for Pediatric House Officers. 18th ed. Philadelphia, PA: Elsevier Mosby; 2009