Polymerase activity of hybrid ribonucleoprotein complexes generated from reassortment between 2009 pandemic H1N1 and seasonal H3N2 influenza A viruses

Virology Journal

Volumn 8, Issue , 2011, Pages

  Lam, Wai Y ^a   Ngai, Karry L K ^a   Chan, Paul K S ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Human swine influenza; NP; PA; Pandemic; Pathogenesis; PB1; PB2; RNA polymerase; RNP; Seasonal

Indexed keywords

ACID PROTEIN; BASIC PROTEIN; HYBRID PROTEIN; RIBONUCLEOPROTEIN; RNA POLYMERASE; VIRUS PROTEIN;

ARTICLE; COLD SENSITIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC REASSORTMENT; HOST RANGE; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; NONHUMAN; VIRUS SURVIVAL;

CELL LINE; DNA-DIRECTED DNA POLYMERASE; GENES, REPORTER; GENETIC ENGINEERING; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA, HUMAN; LUCIFERASES; PANDEMICS; REASSORTANT VIRUSES; RECOMBINANT PROTEINS; RIBONUCLEOPROTEINS; VIRAL PROTEINS;

AVES; INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE; SUIDAE;

EID: 83155163766     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-528     Document Type: Article

References (45)

1. Update: novel influenza A (H1N1) virus infection - Mexico March-May, 2009. Centers for Disease Control and Prevention (CDC), MMWR Morb Mortal Wkly Rep 2009 58 585 589 19498336
2. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, Muramoto Y, Tamura D, Sakai-Tagawa Y, Noda T, et al. Nature 2009 460 1021 1025 19672242
3. Artificial hybrids of influenza A virus RNA polymerase reveal PA subunit modulates its thermal sensitivity. Kashiwagi T, Hara K, Nakazono Y, Hamada N, Watanabe H, PLoS One 2010 5 15140 10.1371/journal.pone.0015140 21151876
4. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. Dawood FS, Jain S, Finelli L, Shaw MW, Lindstrom S, Garten RJ, Gubareva LV, Xu X, Bridges CB, Uyeki TM, N Engl J Med 2009 360 2605 2615 19423869
5. Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans. Peiris JS, Poon LL, Guan Y, J Clin Virol 2009 45 169 173 10.1016/j.jcv.2009.06.006 19540800
6. Update: novel influenza A (H1N1) virus infections - orldwide, May 6, 2009. Centers for Disease Control and Prevention (CDC), MMWR Morb Mortal Wkly Rep 2009 58 453 458
7. World Health Organization (WHO) 2010. Pandemic (H1N1) 2009, http://wwwwhoint/csr/disease/swineflu/en/indexhtml
8. Replication of avian influenza viruses in humans. Beare AS, Webster RG, Arch Virol 1991 119 37 42 10.1007/BF01314321 1863223
9. Human influenza a viral genes responsible for the restriction of its replication in duck intestine. Hatta M, Halfmann P, Wells K, Kawaoka Y, Virology 2002 295 250 255 10.1006/viro.2002.1358 12033783 (Pubitemid 34921310)
10. Reassortant virus derived from avian and human influenza A viruses is attenuated and immunogenic in monkeys. Murphy BR, Sly DL, Tierney EL, Hosier NT, Massicot JG, London WT, Chanock RM, Webster RG, Hinshaw VS, Science 1982 218 1330 1332 10.1126/science.6183749 6183749 (Pubitemid 13225401)
11. Update on avian influenza A (H5N1) virus infection in humans. Abdel-Ghafar AN, Chotpitayasunondh T, Gao Z, Hayden FG, Nguyen DH, de Jong MD, Naghdaliyev A, Peiris JS, Shindo N, Soeroso S, et al. N Engl J Med 2008 358 261 273 18199865
12. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Hatta M, Gao P, Halfmann P, Kawaoka Y, Science 2001 293 1840 1842 10.1126/science.1062882 11546875 (Pubitemid 32845783)
13. Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity. Leung BW, Chen H, Brownlee GG, Virology 2010 401 96 106 10.1016/j.virol.2010.01.036 20211480
14. Orthomyxoviridae: the viruses and their replication. Palese P, Shaw ML, Fields Virology Philadelphia, PA: Lippincott Williams & Wilkins, Knipe DM, Howley RM, 5 1647 1689
15. The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit. Dias A, Bouvier D, Crepin T, McCarthy AA, Hart DJ, Baudin F, Cusack S, Ruigrok RW, Nature 2009 458 914 918 10.1038/nature07745 19194459
16. Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site. Hara K, Shiota M, Kido H, Ohtsu Y, Kashiwagi T, Iwahashi J, Hamada N, Mizoue K, Tsumura N, Kato H, et al. Genes Cells 2001 6 87 97 10.1046/j.1365-2443.2001.00399.x 11260254 (Pubitemid 32266486)
17. Amino acid residues in the N-terminal region of the PA subunit of influenza A virus RNA polymerase play a critical role in protein stability, endonuclease activity, cap binding, and virion RNA promoter binding. Hara K, Schmidt FI, Crow M, Brownlee GG, J Virol 2006 80 7789 7798 10.1128/JVI.00600-06 16873236 (Pubitemid 44182280)
18. The structural basis for an essential subunit interaction in influenza virus RNA polymerase. Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY, Nature 2008 454 1127 1131 10.1038/nature07225 18660801
19. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, et al. Nature 2009 458 909 913 10.1038/nature07720 19194458
20. A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs. Fodor E, Crow M, Mingay LJ, Deng T, Sharps J, Fechter P, Brownlee GG, J Virol 2002 76 8989 9001 10.1128/JVI.76.18.8989-9001.2002 12186883 (Pubitemid 34919858)
21. Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding. Maier HJ, Kashiwagi T, Hara K, Brownlee GG, Virology 2008 370 194 204 10.1016/j.virol.2007.08.029 17905403 (Pubitemid 350179919)
22. RNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites. Li ML, Ramirez BC, Krug RM, EMBO J 1998 17 5844 5852 10.1093/emboj/17.19.5844 9755184 (Pubitemid 28445995)
23. The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits. Li ML, Rao P, Krug RM, EMBO J 2001 20 2078 2086 10.1093/emboj/20.8.2078 11296240 (Pubitemid 32397409)
24. Distinct regions of influenza virus PB1 polymerase subunit recognize vRNA and cRNA templates. Gonzalez S, Ortin J, EMBO J 1999 18 3767 3775 10.1093/emboj/18.13.3767 10393191 (Pubitemid 29308855)
25. A new promoter-binding site in the PB1 subunit of the influenza A virus polymerase. Jung TE, Brownlee GG, J Gen Virol 2006 87 679 688 10.1099/vir.0.81453-0 16476991
26. Two aromatic residues in the PB2 subunit of influenza A RNA polymerase are crucial for cap binding. Fechter P, Mingay L, Sharps J, Chambers A, Fodor E, Brownlee GG, J Biol Chem 2003 278 20381 20388 10.1074/jbc.M300130200 12646557 (Pubitemid 36799239)
27. The structural basis for cap binding by influenza virus polymerase subunit PB2. Guilligay D, Tarendeau F, Resa-Infante P, Coloma R, Crepin T, Sehr P, Lewis J, Ruigrok RW, Ortin J, Hart DJ, et al. Nat Struct Mol Biol 2008 15 500 506 10.1038/nsmb.1421 18454157 (Pubitemid 351653591)
28. Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells. Labadie K, Dos Santos AE, Rameix-Welti MA, van der WS, Naffakh N, Virology 2007 362 271 282 10.1016/j.virol.2006.12.027 17270230 (Pubitemid 46678147)
29. A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. Subbarao EK, London W, Murphy BR, J Virol 1993 67 1761 1764 8445709 (Pubitemid 23088345)
30. The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Gabriel G, Dauber B, Wolff T, Planz O, Klenk HD, Stech J, Proc Natl Acad Sci USA 2005 102 18590 18595 10.1073/pnas.0507415102 16339318 (Pubitemid 43011270)
31. Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model. Li Z, Chen H, Jiao P, Deng G, Tian G, Li Y, Hoffmann E, Webster RG, Matsuoka Y, Yu K, J Virol 2005 79 12058 12064 10.1128/JVI.79.18. 12058-12064.2005 16140781 (Pubitemid 41279322)
32. Co-infection with pandemic H1N1 and seasonal H3N2 influenza viruses. Lee N, Chan PK, Lam WY, Szeto CC, Hui DS, Ann Intern Med 2010 152 618 619 20439587
33. The RNA polymerase of influenza a virus is stabilized by interaction with its viral RNA promoter. Brownlee GG, Sharps JL, J Virol 2002 76 7103 7113 10.1128/JVI.76.14.7103-7113.2002 12072510 (Pubitemid 41246224)
34. The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding. Kashiwagi T, Leung BW, Deng T, Chen H, Brownlee GG, PLoS One 2009 4 5473 10.1371/journal. pone.0005473 19421324
35. Virulence and Genetic Compatibility of Polymerase Reassortant Viruses Derived from the Pandemic (H1N1) 2009 Influenza Virus and Circulating Influenza A Viruses. Song MS, Pascua PN, Lee JH, Baek YH, Park KJ, Kwon HI, Park SJ, Kim CJ, Kim H, Webby RJ, et al. J Virol 2011 85 6275 6286 10.1128/JVI.02125-10 21507962
36. Selection of H5N1 influenza virus PB2 during replication in humans. Le QM, Sakai-Tagawa Y, Ozawa M, Ito M, Kawaoka Y, J Virol 2009 83 5278 5281 10.1128/JVI.00063-09 19264775
37. PB2 protein of a highly pathogenic avian influenza virus strain A/chicken/Yamaguchi/7/2004 (H5N1) determines its replication potential in pigs. Manzoor R, Sakoda Y, Nomura N, Tsuda Y, Ozaki H, Okamatsu M, Kida H, J Virol 2009 83 1572 1578 10.1128/JVI.01879-08 19052090
38. Recent H5N1 avian influenza A virus increases rapidly in virulence to mice after a single passage in mice. Mase M, Tanimura N, Imada T, Okamatsu M, Tsukamoto K, Yamaguchi S, J Gen Virol 2006 87 3655 3659 10.1099/vir.0.81843-0 17098982 (Pubitemid 44816999)
39. Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627 K or 627E/701 N. Steel J, Lowen AC, Mubareka S, Palese P, PLoS Pathog 2009 5 1000252 10.1371/journal.ppat.1000252 19119420
40. Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Subbarao K, Klimov A, Katz J, Regnery H, Lim W, Hall H, Perdue M, Swayne D, Bender C, Huang J, et al. Science 1998 279 393 396 10.1126/science.279.5349.393 9430591 (Pubitemid 28063376)
41. Identification of two separate domains in the influenza virus PB1 protein involved in the interaction with the PB2 and PA subunits: a model for the viral RNA polymerase structure. Gonzalez S, Zurcher T, Ortin J, Nucleic Acids Res 1996 24 4456 4463 10.1093/nar/24.22.4456 8948635 (Pubitemid 26388631)
42. Fine mapping of the subunit binding sites of influenza virus RNA polymerase. Ohtsu Y, Honda Y, Sakata Y, Kato H, Toyoda T, Microbiol Immunol 2002 46 167 175 12008925 (Pubitemid 34289012)
43. Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase. Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY, EMBO J 2009 28 1803 1811 10.1038/emboj.2009.138 19461581
44. Detection and characterization of influenza A virus PA-PB2 interaction through a bimolecular fluorescence complementation assay. Hemerka JN, Wang D, Weng Y, Lu W, Kaushik RS, Jin J, Harmon AF, Li F, J Virol 2009 83 3944 3955 10.1128/JVI.02300-08 19193801
45. Rescue of influenza A virus from recombinant DNA. Fodor E, Devenish L, Engelhardt OG, Palese P, Brownlee GG, Garcia-Sastre A, J Virol 1999 73 9679 9682 10516084 (Pubitemid 29487131)