Novel curcumin analogs, GO-Y030 and GO-Y078, are multitargeted agents with enhanced abilities for multiple myeloma

Anticancer Research

Volumn 31, Issue 11, 2011, Pages 3719-3726

  Kudo, Chieko ^a,b   Yamakoshi, Hiroyuki ^b   Sato, Atsuko ^b   Ohori, Hisatsugu ^b   Ishioka, Chikashi ^b   Iwabuchi, Yoshiharu ^b   Shibata, Hiroyuki ^a  

^a AKITA UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Curcumin analog; IRF4; JAK STAT3; Multiple myeloma; NF B; PI3K AKT

Indexed keywords

BORTEZOMIB; CURCUMIN; GO Y 030; GO Y 078; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 6; JANUS KINASE; MELPHALAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; THALIDOMIDE; UNCLASSIFIED DRUG;

ARTICLE; CYTOKINE PRODUCTION; DRUG MECHANISM; HUMAN; HUMAN CELL; INHIBITION KINETICS; MOLECULARLY TARGETED THERAPY; MULTIPLE MYELOMA; MYELOMA CELL; PRIORITY JOURNAL; SYNTHESIS;

APOPTOSIS; BENZENE DERIVATIVES; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CURCUMIN; FLOW CYTOMETRY; HUMANS; INTERFERON REGULATORY FACTORS; INTERLEUKIN-6; JANUS KINASE 1; KETONES; MULTIPLE MYELOMA; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TUMOR CELLS, CULTURED;

EID: 83055191355     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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