Dorsal root ganglion neurons with dichotomizing axons projecting to the hip joint and the knee skin in rats: Possible mechanism of referred knee pain in hip joint disease

Journal of Orthopaedic Science

Volumn 16, Issue 6, 2011, Pages 799-804

  Miura, Yoko ^a   Ohtori, Seiji ^a   Nakajima, Takayuki ^a   Kishida, Shinji ^a   Harada, Yoshitada ^a   Takahashi, Kazuhisa ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,1' DIOCTADECYL 3,3,3',3' TETRAMETHYLINDOCARBOCYANINE; CALCITONIN GENE RELATED PEPTIDE; FLUOROGOLD; NEUROPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL ROOT GANGLION NEURON; HIP; HIP DISEASE; HIP PAIN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INNERVATION; KNEE; LUMBAR SPINE; NERVE CELL; NERVE FIBER; NONHUMAN; RAT; REFERRED PAIN; SKIN;

EID: 83055186616     PISSN: 09492658     EISSN: 14362023     Source Type: Journal    
DOI: 10.1007/s00776-011-0144-1     Document Type: Article

References (24)

1. AM Khan E McLoughlin K Giannakas C Hutchinson JG Andrew 2004 Hip osteoarthritis: where is the pain? Ann R Coll Surg Engl 86 119 121 15005931 1:STN:280:DC%2BD2c7hsF2luw%3D%3D (Pubitemid 38332233)
2. Ruch TC. Visceral sensation and referred pain. In: Fulton JF, editor. Howell's textbook of physiology. 15th ed. Philadelphia: WB Saunders; 1946. p. 385-401.
3. RD Foreman RN Weber 1980 Responses from neurons of the primate spinothalamic tract to electrical stimulation of afferents from the cardiopulmonary region and somatic structures Brain Res 186 463 468 6766786 1:STN:280:DyaL3c7jtF2itA%3D%3D (Pubitemid 10109529)
4. HK Rucker JA Holloway 1982 Viscerosomatic convergence onto spinothalamic tract neurons in the cat Brain Res 243 155 157 7116151 1:STN:280: DyaL3s%2FgtFehsQ%3D%3D (Pubitemid 12082374)
5. M Selzer WA Spencer 1969 Convergence of visceral and cutaneous afferent pathways in the lumber spinal cord Brain Res 14 331 348 5794911 1:STN:280:DyaF1M3js1GitA%3D%3D
6. DC Sinclair G Weddell WH Feindel 1948 Referred pain and associated phenomena Brain 71 184 211 18890914 1:STN:280:DyaH1c%2FjsVKlsw%3D%3D
7. NQ Khan ST Woolson 1998 Referral patterns of hip pain in patients undergoing total hip replacement Orthopedics 21 123 126 9507264 1:STN:280:DyaK1c7mvVWjtA%3D%3D
8. T Nakajima S Ohtori G Inoue T Koshi S Yamamoto J Nakamura K Takahashi Y Harada 2008 The characteristics of dorsal-root ganglia and sensory innervation of the hip in rats J Bone Joint Surg [Br] 90 254 257 1:STN:280: DC%2BD1c%2FpvVKqsg%3D%3D (Pubitemid 351303359)
9. FK Pierau G Fellmer DC Taylor 1984 Somato-visceral convergence in cat dorsal root ganglion neurones demonstrated by double-labelling with fluorescent tracers Brain Res 321 63 70 6208979 1:STN:280:DyaL2M%2FkvVSksg%3D%3D (Pubitemid 15176895)
10. H Schmid DC Taylor FK Pierau 1983 Tracing of sensory neurones and spinal motoneurones of the pigeon by injection of fluorescent dyes into peripheral nerves Cell Tissue Res 232 9 19 6883441 1:STN:280:DyaL3s3osFWnsg%3D%3D (Pubitemid 13074974)
11. DC Taylor FK Pierau 1982 Double fluorescence labelling supports electrophysiological evidence for dichotomizing peripheral sensory nerve fibres in rats Neurosci Lett 33 1 6 6296733 1:STN:280:DyaL3s7hsFyjtA%3D%3D (Pubitemid 13220356)
12. DC Taylor FK Pierau H Schmid 1983 The use of fluorescent tracers in the peripheral sensory nervous system J Neurosci Methods 8 221 224
13. HJ Habler W Jang M Koltzenburg 1988 Dichotomizing unmyelinated afferents supplying pelvic viscera and perineum are rare in the sacral segments of the cat Neurosci Lett 94 119 124 3241660 1:STN:280:DyaL1M3gtFGjuw%3D%3D
14. FK Pierau DC Taylor W Abel B Friedrich 1982 Dichotomizing peripheral fibres revealed by intracellular recording from rat sensory neurones Neurosci Lett 31 123 128 7133547 1:STN:280:DyaL3s%2FjslKlsw%3D%3D (Pubitemid 13230530)
15. K Birnbaum A Prescher S Hepler D Heller 1997 The sensory innervation of the hip joint-an anatomical study Surg Radiol Anat 19 371 375 9479711 1:STN:280:DyaK1c7ktVegug%3D%3D (Pubitemid 28017958)
16. T Hökfelt 1991 Neuropeptides in perspective: the last ten years Neuron 7 867 879 1684901
17. PW McCarthy SN Lawson 1990 Cell type and conduction velocity of rat primary sensory neurons with calcitonin gene-related peptide-like immunoreactivity Neuroscience 34 623 632 2352644 1:CAS:528:DyaK3cXkvFWksLg%3D (Pubitemid 20146726)
18. G Saxler F Löer M Skumavc J Pförtner U Hanesch 2007 Localization of SP- and CGRP-immunopositive nerve fibers in the hip joint of patients with painful osteoarthritis and of patients with painless failed total hip arthroplasties Eur J Pain 11 67 74 16460974 (Pubitemid 44636277)
19. G Saxler F Löer M von Knoch F von Knoch U Hanesch 2005 Localization of the neurokinin 1 receptor in hip joints of patients with painful osteoarthritis Z Orthop Ihre Grenzgeb 143 424 430 16118758 1:STN:280: DC%2BD2MvltFyhsg%3D%3D (Pubitemid 41274885)
20. Y Takahashi S Ohtori K Takahashi 2010 Sclerotomes in the thoracic and lumbar spine, pelvis, and hindlimb bones of rats J Pain 11 652 662 20335076
21. PD Wall CJ Woolf 1984 Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat J Physiol 356 443 458 6520794 1:STN:280:DyaL2M7gslOmsA%3D%3D (Pubitemid 14011558)
22. KA Sluka 2002 Stimulation of deep somatic tissue with capsaicin produces long-lasting mechanical allodynia and heat hypoalgesia that depends on early activation of the cAMP pathway J Neurosci 22 5687 5693 12097520 1:CAS:528:DC%2BD38XltF2mtL4%3D (Pubitemid 35386490)
23. N Ochiai S Ohtori T Sasho K Nakagawa K Takahashi N Takahashi R Murata K Takahashi H Moriya Y Wada T Saisu 2007 Extracorporeal shock wave therapy improves motor dysfunction and pain originating from knee osteoarthritis in rats Osteoarthr Cartil 15 1093 1096 17466542 1:STN:280:DC%2BD2srjvFCnsA%3D%3D (Pubitemid 47387039)
24. DB Mach SD Rogers MC Sabino NM Luger MJ Schwei JD Pomonis CP Keyser DR Clohisy DJ Adams P O'Leary PW Mantyh 2002 Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur Neuroscience 113 155 166 12123694 1:CAS:528:DC%2BD38Xlt1OiurY%3D (Pubitemid 34786021)