Localization of SP- and CGRP-immunopositive nerve fibers in the hip joint of patients with painful osteoarthritis and of patients with painless failed total hip arthroplasties

European Journal of Pain

Volumn 11, Issue 1, 2007, Pages 67-

  Saxler, Guido ^a   Löer, Franz ^a   Skumavc, Marc ^a   Pförtner, Jörg ^a   Hanesch, Ulrike ^b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF LUXEMBOURG   (Luxembourg)

Author keywords

Failed total hip arthroplasties; Human hip joint; Osteoarthritis; Pain; SP , CGRP immunopositive nerve fibers

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; SUBSTANCE P;

ACETABULUM; ADULT; AGED; ARTHRALGIA; ARTICLE; CELLULAR DISTRIBUTION; CLINICAL OBSERVATION; CONTROLLED STUDY; DENERVATION; FEMALE; FEMUR NECK FRACTURE; HIP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INNERVATION; JOINT CAPSULE; LOCAL THERAPY; MALE; NERVE FIBER; NOCICEPTION; NOCICEPTIVE STIMULATION; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SOFT TISSUE; SYNOVECTOMY; SYNOVIUM; TOTAL HIP PROSTHESIS; TREATMENT FAILURE; UPREGULATION;

EID: 33750323782     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2005.12.011     Document Type: Article

References (41)

1. Ahmed M., Bergstrom J., Lundblad H., Gillespie W.J., and Kreicbergs A. Sensory nerves in the interface membrane of aseptic loose hip prostheses. J Bone Joint Surg (Br) 80 (1998) 151-155
2. Barden B., and Huttegger C. Failure mechanisms in total hip and knee arthroplasty: a morphologic and radiologic study. Mat-Wiss und Werkstofftech 30 (1999) 746-754
3. In: Bauer R., Kerschbaumer F., and Poisel S. (Eds). Operative Zugangswege in der Orthopädie und Traumatologie. Becken und untere Extremität (1994), Thieme, Stuttgart, New York 114-116
4. In: Benninghoff A., and Drenckhahn D. (Eds). Anatomie, Makroskopische Anatomie, Histologie, Embryologie, Zellbiologie (2003), Urban & Fischer Verlag, München, Jena 353f
5. Bjurholm A., Ahmed M., Svenson S.B., Kreicbergs A., and Schultzberg M. Interleukin-1 immunoreactive nerve fibers in rat joint synovium. Clin Exp Rheumatol 12 (1994) 583-587
6. Bulling D.G., Kelly D., Bond S., McQueen D.S., and Seckl J.R. Adjuvant-induced joint inflammation causes very rapid transcription of beta-preprotachykinin and alpha-CGRP genes in innervating sensory ganglia. J Neurochem 77 (2001) 372-382
7. Buma P. Innervation of the patella. An immunohistochemical study in mice. Acta Orthop Scand 65 (1994) 80-86
8. Caron J.P., Bowker R.M., Abhold R.H., Toppin D.S., Sonea I.M., and Vex K.B. Substance P in the synovial membrane and fluid of the equine middle carpal joint. Equine Vet J 24 (1992) 364-366
9. In: Der G., and Everitt B.S. (Eds). A handbook of statistical analyses using SAS. 2nd ed. (2002), Chapman and Hall, Boca Raton, Florida
10. Felson D.T., and Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum 41 (1998) 1343-1355
11. Fortier L.A., and Nixon A.J. Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations. J Rheumatol 24 (1997) 524-530
12. Hanesch U., Heppelmann B., and Schmidt R.F. Substance P- and calcitonin gene-related peptide immunoreactivity in primary afferent neurons of the cat's knee joint. Neuroscience 45 (1991) 185-193
13. Hanesch U., Pfrommer U., Grubb B.D., Heppelmann B., and Schaible H.G. The proportion of CGRP-immunoreactive and SP-mRNA containing dorsal root ganglion cells is increased by a unilateral inflammation of the ankle joint of the rat. Regul Pept 46 (1993) 202-203
14. Hanesch U., Heppelmann B., and Schmidt R.F. Somatostatin-like immunoreactivity in primary afferents of the medial articular nerve and colocalization with substance P in the cat. J Comp Neurol 354 (1995) 345-352
15. Hanesch U., Heppelmann B., and Schmidt R.F. Quantification of cat's articular afferents containing calcitonin gene-related peptide or substance P innervating normal and acutely inflamed knee joints. Neurosci Lett 233 (1997) 105-108
16. Heppelmann B., and Pawlak M. Sensitization of articular afferents in normal and inflamed knee joints by substance P in the rat. Neurosci Lett 223 (1997) 97-100
17. Heppelmann B., Shahbazian Z., and Hanesch U. Quantitative examination of calcitonin gene-related peptide immunoreactive nerve fibers in the cat knee joint capsule. Anat Embryol (Berl) 195 (1997) 525-530
18. Hukkanen M., Konttinen Y.T., Rees R.G., Gibson S.J., Santavirta S., and Polak J.M. Innervation of bone from healthy and arthritic rats by substance P and calcitonin gene related peptide containing sensory fibers. J Rheumatol 19 (1992) 1252-1259
19. Kirker-Head C.A., Chandna V.K., Agarwal R.K., Morris E.A., Tidwell A., O'Callaghan M.W., et al. Concentrations of substance P and prostaglandin E2 in synovial fluid of normal and abnormal joints of horses. Am J Vet Res 61 (2000) 714-718
20. Lam F.Y., and Ferrell W.R. Inhibition of carrageenan induced inflammation in the rat knee joint by substance P antagonist. Ann Rheum Dis 48 (1989) 928-932
21. Lembeck F., Folkers K., and Donnerer J. Analgesic effect of antagonists of substance P. Biochem Biophys Res Commun 103 (1981) 1318-1321
22. Levine J.D., Clark R., Devor M., Helms C., Moskowitz M.A., and Basbaum A.I. Intraneuronal substance P contributes to the severity of experimental arthritis. Science 226 (1984) 547-549
23. Lievense A.M., Bierma-Zeinstra S.M., Verhagen A.P., van Baar M.E., Verhaar J.A., and Koes B.W. Influence of obesity on the development of osteoarthritis of the hip: a systematic review. Rheumatology (Oxford) 41 (2002) 1155-1162
24. Marshall K.W., Chiu B., and Inman R.D. Substance P and arthritis: analysis of plasma and synovial fluid levels. Arthritis Rheum 33 (1990) 87-90
25. Marshall K.W., Theriault E., and Homonko D.A. Distribution of substance P and calcitonin gene related peptide immunoreactivity in the normal feline knee. J Rheumatol 21 (1994) 883-889
26. Miller M.E., Rejeski W.J., Messier S.P., and Loeser R.F. Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors OASIS. Arthritis Rheum 45 (2001) 331-339
27. Myers S.L., Brandt K.D., Ehlich J.W., Braunstein E.M., Shelbourne K.D., Heck D.A., et al. Synovial inflammation in patients with early osteoarthritis of the knee. J Rheumatol 17 (1990) 1662-1669
28. Niissalo S., Li T.F., Santavirta S., Takagi M., Hietanen J., and Konttinen Y.T. Dense innervation in pseudocapsular tissue compared to aneural interface tissue in loose totally replaced hips. J Rheumatol 29 (2002) 796-803
29. Pawlak M., Schmidt R.F., Heppelmann B., and Hanesch U. The neurokinin-1 receptor antagonist RP 67580 reduces the sensitization of primary afferents by substance P in the rat. Eur J Pain 5 (2001) 69-79
30. Saxler G., Löer F., von Knoch M., von Knoch F., and Hanesch U. Localization of the neurokinin 1 receptor in hip joints of patients with painful osteoarthritis. Z Orthop Ihre Grenzgeb 143 (2005) 424-430
31. Schwab W., Bilgicyildirim A., and Funk R.H. Microtopography of the autonomic nerves in the rat knee: a fluorescence microscopic study. Anat Rec 247 (1997) 109-118
32. Sluka K.A., and Westlund K.N. Behavioral and immunohistochemical changes in an experimental arthritis model in rats. Pain 55 (1993) 367-377
33. Tahmasebi-Sarvestani A., Tedman R., and Goss A.N. The influence of experimentally induced osteoarthrosis on articular nerve fibers of the sheep temporomandibular joint. J Orofac Pain 15 (2001) 206-217
34. Tamura R., Hanesch U., Schmidt R.F., Kumazawa T., and Mizumura K. Examination of colocalization of calcitonin gene-related peptide- and substance P-like immunoreactivity in the knee joint of the dog. Neurosci Lett 254 (1998) 53-56
35. Walsh D.A., Salmon M., Mapp P.I., Wharton J., Garrett N., Blake D.R., et al. Microvascular substance P binding to normal and inflamed rat and human synovium. J Pharmacol Exp Ther 267 (1993) 951-960
36. White D.M., and Helme R.D. Release of substance P from peripheral nerve terminals following electrical stimulation of the sciatic nerve. Brain Res 336 (1985) 27-31
37. Witonski D., and Wagrowska-Danielewicz M. Distribution of substance-P nerve fibers in the knee joint in patients with anterior knee pain syndrome. A preliminary report. Knee Surg Sports Traumatol Arthrosc 7 (1999) 177-183
38. Wojtys E.M., Beaman D.N., Glover R.A., and Janda D. Innervation of the human knee joint by substance-P fibers. Arthroscopy 6 (1990) 254-263
39. Wu Z., Nagata K., and Iijima T. Immunohistochemical study of NGF and its receptors in the synovial membrane of the ankle joint of adjuvant-induced arthritic rats. Histochem Cell Biol 114 (2000) 453-459
40. Yelin E.H., Trupin L.S., and Sebesta D.S. Transitions in employment, morbidity, and disability among persons ages 51-61 with musculoskeletal and non-musculoskeletal conditions in the US, 1992-1994. Arthritis Rheum 42 (1999) 769-779
41. Yoshida H., Fujita S., Nishida M., and Iizuka T. The expression of substance P in human temporomandibular joint samples: an immunohistochemical study. J Oral Rehabil 26 (1999) 338-344