Cross-sectional study of bone metabolism with nutrition in adult classical phenylketonuric patients diagnosed by neonatal screening

Journal of Bone and Mineral Metabolism

Volumn 29, Issue 6, 2011, Pages 737-743

  Nagasaka, Hironori ^a   Tsukahara, Hirokazu ^b   Takatani, Tomozumi ^c   Sanayama, Yoshitami ^d   Takayanagi, Masaki ^d   Ohura, Toshihiro ^e   Sakamoto, Osamu ^e   Ito, Tetsuya ^f   Wada, Mika ^g   Yoshino, Makoto ^h   Ohtake, Akira ⁱ   Yorifuji, Tohru ^j   Hirayama, Satoshi ^k   Miida, Takashi ^k   Fujimoto, Hiroki ^m   Mochizuki, Hiroshi ^l   Hattori, Toshikazu ^m   Okano, Yoshiyuki ⁿ  

^a TAKARAZUKA CITY HOSPITAL   (Japan)

^b OKAYAMA UNIVERSITY HOSPITAL   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d CHIBA CHILDREN'S HOSPITAL   (Japan)

^e TOHOKU UNIVERSITY HOSPITAL   (Japan)

^f NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^g NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^h Kurume University Graduate School of Medicine Kurume University Graduate School of Medicine Graduate School Biostatistics   (Japan)

ⁱ SAITAMA MEDICAL UNIVERSITY   (Japan)

^j OSAKA CITY GENERAL HOSPITAL   (Japan)

^k JUNTENDO UNIVERSITY   (Japan)

^l SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

^m OSAKA CITY UNIVERSITY HOSPITAL   (Japan)

ⁿ OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

more..

Author keywords

Adult; Bone resorption; Classical phenylketonuria; Osteopenia; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM; OSTEOPROTEGERIN; PARATHYROID HORMONE; PHENYLALANINE 4 MONOOXYGENASE;

ADULT; ARTICLE; BONE METABOLISM; BONE TURNOVER; CALCIUM URINE LEVEL; CALORIC INTAKE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENERGY CONSUMPTION; ENZYME BLOOD LEVEL; FEMALE; HUMAN; MALE; NEWBORN SCREENING; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; OSTEOLYSIS; PARATHYROID HORMONE BLOOD LEVEL; PHENYLKETONURIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN INTAKE; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

ADULT; BONE AND BONES; BONE DISEASES, METABOLIC; BONE RESORPTION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFANT, NEWBORN; MALE; NEONATAL SCREENING; PARATHYROID HORMONE; PHENYLKETONURIAS; VITAMIN D; YOUNG ADULT;

EID: 83055181556     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-011-0276-6     Document Type: Article

References (31)

1. Scriver CR, Kaufman S (2001) Hyperphenylalaninemia: phenylalanine hydroxylase deficiency. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The metabolic and molecular bases of inherited disease, 8th edn. McGraw-Hill, New York, pp 1667-1724
2. HC Curtius A Niederwieser M Viscontini W Leimbacher H Wegmann B Blehova F Rey J Schaub H Schmidt 1981 Serotonin and dopamine synthesis in phenylketonuria Adv Exp Med Biol 133 277 291 6119011 1:STN:280:DyaL38%2FovVWntA%3D%3D
3. E Herrero MC Aragon C Gimenez F Valdivieso 1983 Inhibition by l-phenylalanine of tryptophan transport by synaptosomal plasma membrane vesicles: implications in the pathogenesis of phenylketonuria J Inherit Metab Dis 6 32 35 6408306 10.1007/BF02391190 1:CAS:528:DyaL3sXhvFGqt7g%3D (Pubitemid 13128101)
4. R Burri C Steffen S Stieger U Brodbeck JP Colombo N Herschkowitz 1990 Reduced myelinogenesis and recovery in hyperphenylalaninemic rats. Correlation between brain phenylalanine levels, characteristic brain enzymes for myelination, and brain development Mol Chem Neuropathol 13 57 69 2095783 10.1007/BF03159908 1:CAS:528:DyaK3MXmtVGisbY%3D
5. H Przyrembel HJ Bremer 2000 Nutrition, physical growth and bone density in treated phenylketonuria Eur J Pediatr 159 (suppl 2) S129 S135 10.1007/PL00014376
6. L Hillman C Schlotzhauer D Lee J Grasela S Witter S Allen R Hillman 1996 Decreased bone mineralization in children with phenylketonuria under treatment Eur J Pediatr 155 (suppl 1) S148 S152 10.1007/PL00014234
7. B Schwahn E Mokov K Scheidhauer B Lettgen E Schönau 1998 Decreased trabecular bone mineral density in patients with phenylketonuria measured by peripheral quantitative computed tomography Acta Pediatr 87 61 63 10.1111/j.1651-2227.1998.tb01387.x 1:STN:280:DyaK1c7mvFaksw%3D%3D (Pubitemid 28086607)
8. P Barat N Barthe I Redonnet-Vernhet F Parrot 2002 The impact of the control of serum phenylalanine levels on osteopenia in patients with phenylketonuria Eur J Pediatr 161 687 688 12536994 10.1007/s00431-002-1091-9 1:CAS:528:DC%2BD3sXlt1Wjsw%3D%3D (Pubitemid 35435545)
9. P Millet MA Vilaseca C Valls B Pérez-Dueñas R Artuch L Gómez N Lambruschini J Campistol 2005 Is deoxypyridinoline a good resorption marker to detect osteopenia in phenylketonuria? Clin Biochem 38 1127 1132 16256974 10.1016/j.clinbiochem.2005.09.002 1:CAS:528:DC%2BD2MXhtlaisbnP (Pubitemid 41797754)
10. J Ambroszkiewicz J Gajewska T Laskowska-Klita 2004 A study of bone turnover markers in prepubertal children with phenylketonuria Eur J Pediatr 163 177 178 14749925 10.1007/s00431-003-1394-5 (Pubitemid 38328071)
11. A AI-Qadreh KH Schulpis H Athanasopoulou C Mengreli A Skarpalezou I Voskaki 1998 Bone mineral status in children with phenylketonuria under treatment Acta Pediatr 87 1162 1166 10.1111/j.1651-2227.1998.tb00924.x (Pubitemid 28538426)
12. D Modan-Moses I Vered G Schwartz Y Anikster S Abraham R Segev O Efrati, et al. 2007 Peak bone mass in patients with phenylketonuria J Inherit Metab Dis 30 202 208 17347917 10.1007/s10545-007-0462-9 1:STN:280:DC%2BD2s7nt1Wgsw%3D%3D (Pubitemid 46488002)
13. F Pagani CM Francucci L Moro 2005 Markers of bone turnover: biochemical and clinical perspectives J Endocrinol Invest 28 (suppl 10) 8 13
14. P Szulc E Seeman PD Delmas 2000 Biochemical measurements of bone turnover in children and adolescents Osteoporos Int 11 281 294 10928217 10.1007/s001980070116 1:CAS:528:DC%2BD3cXmtVaktrY%3D (Pubitemid 30417180)
15. T Tamada T Sone T Tomomitsu Y Jo H Tanaka M Fukunaga 2001 Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy J Bone Miner Metab 19 45 51 11156473 10.1007/s007740170059 1:CAS:528:DC%2BD3MXhvVGjs7c%3D (Pubitemid 32048197)
16. HL Wright HS McCarthy J Middleton MJ Marshall 2009 RANK, RANKL and osteoprotegerin in bone biology and disease Curr Rev Musculoskelet Med 2 56 64 19468919 10.1007/s12178-009-9046-7 1:STN:280:DC%2BD1MzmvFemuw%3D%3D
17. O Sahota MK Mundey P San IM Godber N Lawson DJ Hosking 2004 The relationship between vitamin D and parathyroid hormone: calcium homeostasis, bone turnover, and bone mineral density in postmenopausal women with established osteoporosis Bone (NY) 35 312 319 1:CAS:528:DC%2BD2cXltVGjsLo%3D (Pubitemid 38789179)
18. P Lips T Duong A Oleksik D Black S Cummings D Cox T Nickelsen 2001 A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial J Clin Endocrinol Metab 86 1212 1221 11238511 10.1210/jc.86.3.1212 1:CAS:528:DC%2BD3MXitFWnt7s%3D (Pubitemid 32323007)
19. H Takayanagi 2005 Osteoimmunological insight into bone damage in rheumatoid arthritis Mod Rheumatol 15 225 231 17029070 10.1007/s10165-005-0398-6 (Pubitemid 41236269)
20. H Takayanagi K Sato A Takaoka T Taniguchi 2005 Interplay between interferon and other cytokine systems in bone metabolism Immunol Rev 208 181 193 16313349 10.1111/j.0105-2896.2005.00337.x 1:CAS:528:DC%2BD28Xks1eiuw%3D%3D (Pubitemid 41746393)
21. G Banfi EL Iorio MM Corsi 2008 Oxidative stress, free radicals and bone remodeling Clin Chem Lab Med 46 1550 1555 18847368 10.1515/CCLM.2008.302 1:CAS:528:DC%2BD1cXhsVOjtLzJ
22. O Altindag O Erel N Soran H Celik S Selek 2008 Total oxidative/anti- oxidative status and relation to bone mineral density in osteoporosis Rheumatol Int 28 317 321 17823800 10.1007/s00296-007-0452-0 1:CAS:528: DC%2BD1cXjsFahsA%3D%3D
23. S Yannicelli DM Medeiros 2002 Elevated plasma phenylalanine concentrations may adversely affect bone status of phenylketonuric mice J Inherit Metab Dis 25 347 361 12408184 10.1023/A:1020191515173 1:CAS:528:DC%2BD38XovVGktLw%3D
24. IP Hargreaves 2007 Coenzyme Q10 in phenylketonuria and mevalonic aciduria Mitochondrion 7 (suppl 1) S175 S180 10.1016/j.mito.2007.02.009 (Pubitemid 46722289)
25. S Shefer GS Tint D Jean-Guillaume E Daikhin A Kendler LB Nguyen M Yudkoff CA Dyer 2000 Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and forebrain pathology in the PKU mouse? J Neurosci Res 61 549 563 10956425 10.1002/1097-4547(20000901)61:5<549::AID- JNR10>3.0.CO;2-0 1:CAS:528:DC%2BD3cXmsFGqur8%3D
26. LR Sirtori CS Dutra-Filho D Fitarelli A Sitta A Haeser AG Barschak M Wajner DM Coelho S Llesuy A Belló-Klein R Giugliani M Deon CR Vargas 2005 Oxidative stress in patients with phenylketonuria Biochim Biophys Acta 1740 68 73 15878743 1:CAS:528:DC%2BD2MXjvVKktLo%3D (Pubitemid 40692700)
27. R Artuch C Colomé C Sierra N Brandi N Lambruschini J Campistol D Ugarte MA Vilaseca 2004 A longitudinal study of antioxidant status in phenylketonuric patients Clin Biochem 37 198 203 14972641 10.1016/j.clinbiochem. 2003.10.017 1:CAS:528:DC%2BD2cXht1yqsL0%3D (Pubitemid 38221567)
28. C Sierra MA Vilaseca D Moyano N Brandi J Campistol N Lambruschini FJ Cambra R Deulofeu A Mira 1998 Antioxidant status in hyperphenylalaninemia Clin Chim Acta 276 1 9 9760015 10.1016/S0009-8981(98)00091-6 1:CAS:528: DyaK1cXltFWktL4%3D (Pubitemid 28386824)
29. M Jevon A Sabokbar Y Fujikawa T Hirayama SD Neale J Wass NA Athanasou 2002 Gender- and age-related differences in osteoclast formation from circulating precursors J Endocrinol 172 673 681 11874715 10.1677/joe.0.1720673 1:CAS:528:DC%2BD38XisVShtL4%3D (Pubitemid 34232708)
30. C Lormeau B Soudan M d'Herbomez P Pigny B Duquesnoy B Cortet, et al. 2004 Sex hormone-binding globulin, estradiol, and bone turnover markers in male osteoporosis Bone (NY) 34 933 939 1:CAS:528:DC%2BD2cXkvV2isbo%3D (Pubitemid 38749230)
31. B Frenkel A Hong SK Baniwal GA Coetzee C Ohlsson O Khalid Y Gabet 2010 Regulation of adult bone turnover by sex steroids J Cell Physiol 224 305 310 20432458 10.1002/jcp.22159 1:CAS:528:DC%2BC3cXmslWiu7s%3D