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Volumn 25, Issue 5, 2011, Pages 495-500

LOX-1: A new target for therapy for cardiovascular diseases

Author keywords

Atherosclerosis; Coronary artery disease; Hypertension; LOX 1; Myocardial ischemia; Oxidative stress

Indexed keywords

ANTIOXIDANT; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1 INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VITAMIN;

EID: 83055181410     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-011-6325-5     Document Type: Article
Times cited : (18)

References (40)
  • 1
    • 0032065601 scopus 로고    scopus 로고
    • Fifty percent of patients with coronary artery disease do not have any of the conventional risk factors
    • LG Futterman L Lemberg 1998 Fifty percent of patients with coronary artery disease do not have any of the conventional risk factors Am J Crit Care 7 240 244 9579251 1:STN:280:DyaK1c3ktVCitg%3D%3D (Pubitemid 128460540)
    • (1998) American Journal of Critical Care , vol.7 , Issue.3 , pp. 240-244
    • Futterman, L.G.1    Lemberg, L.2
  • 2
    • 8344283475 scopus 로고    scopus 로고
    • Reactive oxygen species: Players in the platelet game
    • DOI 10.1161/01.ATV.0000145574.90840.7d
    • F Krötz HY Sohn U Pohl 2004 Reactive oxygen species: players in the platelet game Arterioscler Thromb Vasc Biol 24 1988 96 15374851 10.1161/01.ATV.0000145574.90840.7d (Pubitemid 39482420)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.11 , pp. 1988-1996
    • Krotz, F.1    Sohn, H.-Y.2    Pohl, U.3
  • 4
    • 0034880607 scopus 로고    scopus 로고
    • Reactive oxygen species mediate angiotensin II-induced leukocyte-endothelial cell interactions in vivo
    • A Alvarez MJ Sanz 2001 Reactive oxygen species mediate angiotensin II-induced leukocyte-endothelial cell interactions in vivo J Leukoc Biol 70 199 206 11493611 1:CAS:528:DC%2BD3MXlvFCiurc%3D (Pubitemid 32751510)
    • (2001) Journal of Leukocyte Biology , vol.70 , Issue.2 , pp. 199-206
    • Alvarez, A.1    Sanz, M.-J.2
  • 5
    • 33747883300 scopus 로고    scopus 로고
    • Oxidized or Native Low-Density Lipoprotein Cholesterol Editorials published in the Journal of American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology. Which Is More Important in Atherogenesis?
    • DOI 10.1016/j.jacc.2006.06.001, PII S0735109706014574
    • JL Mehta 2006 Oxidized or native low-density lipoprotein cholesterol which is more important in atherogenesis? J Am Coll Cardiol 48 980 982 16949490 10.1016/j.jacc.2006.06.001 (Pubitemid 44292441)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.5 , pp. 980-982
    • Mehta, J.L.1
  • 7
    • 80052607666 scopus 로고    scopus 로고
    • Oxidative stress and lectin-Like ox-LDL receptor LOX-1 in atherogenesis and tumorigenesis
    • Feb 21, 2011, epub ahead of print
    • Lu J, Mitra S, Wang X, Khaidakov M, Mehta JL. Oxidative stress and lectin-Like ox-LDL receptor LOX-1 in atherogenesis and tumorigenesis.Antioxid Redox Signal. Feb 21, 2011, epub ahead of print
    • Antioxid Redox Signal
    • Lu, J.1    Mitra, S.2    Wang, X.3    Khaidakov, M.4    Mehta, J.L.5
  • 8
    • 27644447314 scopus 로고    scopus 로고
    • Oxidized LDL, a critical factor in atherogenesis
    • DOI 10.1016/j.cardiores.2005.09.009, PII S0008636305004463
    • D Li JL Mehta 2005 Oxidized LDL, a critical factor in atherogenesis Cardiovasc Res 68 353 4 16253212 10.1016/j.cardiores.2005.09.009 1:CAS:528:DC%2BD2MXht1Sqsr3M (Pubitemid 41566554)
    • (2005) Cardiovascular Research , vol.68 , Issue.3 , pp. 353-354
    • Li, D.1    Mehta, J.L.2
  • 9
  • 10
    • 20044383911 scopus 로고    scopus 로고
    • Effects of long-term vitamin E supplementation on cardiovascular events and cancer: A randomized controlled trial
    • DOI 10.1001/jama.293.11.1338
    • E Lonn J Bosch S Yusuf P Sheridan J Pogue JM Arnold C Ross A Arnold P Sleight J Probstfield GR Dagenais 2005 HOPE and HOPE-TOO Trial Investigators. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial JAMA 293 1338 47 15769967 10.1001/jama.293.11.1338 (Pubitemid 40381486)
    • (2005) Journal of the American Medical Association , vol.293 , Issue.11 , pp. 1338-1347
    • Lonn, E.1
  • 12
    • 46749105968 scopus 로고    scopus 로고
    • LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet
    • DOI 10.1093/cvr/cvn110
    • C Hu A Dandapat L Sun J Chen MR Marwali F Romeo T Sawamura JL Mehta 2008 LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet Cardiovasc Res 79 287 93 18453637 10.1093/cvr/cvn110 1:CAS:528: DC%2BD1cXot1Wisrg%3D (Pubitemid 351951615)
    • (2008) Cardiovascular Research , vol.79 , Issue.2 , pp. 287-293
    • Hu, C.1    Dandapat, A.2    Sun, L.3    Chen, J.4    Marwali, M.R.5    Romeo, F.6    Sawamura, T.7    Mehta, J.L.8
  • 16
    • 84864288625 scopus 로고    scopus 로고
    • Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity
    • 19247493 10.1371/journal.pone.0004648
    • S Biocca M Falconi I Filesi F Baldini L Vecchione R Mango F Romeo G Federici A Desideri G Novelli 2009 Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity PLoS One. 4 e4648 19247493 10.1371/journal.pone.0004648
    • (2009) PLoS One. , vol.4 , pp. 4648
    • Biocca, S.1    Falconi, M.2    Filesi, I.3    Baldini, F.4    Vecchione, L.5    Mango, R.6    Romeo, F.7    Federici, G.8    Desideri, A.9    Novelli, G.10
  • 17
    • 79952043054 scopus 로고    scopus 로고
    • Pathogenetic role of eNOS uncoupling in cardiopulmonary disorders
    • 21172428 10.1016/j.freeradbiomed.2010.12.018 1:CAS:528: DC%2BC3MXisFylu7g%3D
    • JF Gielis JY Lin K Wingler, et al. 2011 Pathogenetic role of eNOS uncoupling in cardiopulmonary disorders Free Radic Biol Med. 50 765 76 21172428 10.1016/j.freeradbiomed.2010.12.018 1:CAS:528:DC%2BC3MXisFylu7g%3D
    • (2011) Free Radic Biol Med. , vol.50 , pp. 765-76
    • Gielis, J.F.1    Lin, J.Y.2    Wingler, K.3
  • 19
    • 0026478022 scopus 로고
    • Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
    • 1359209 10.1016/0140-6736(92)93147-F 1:STN:280:DyaK3s%2FmtFGhuw%3D%3D
    • DS Celermajer KE Sorensen VM Gooch DJ Spiegelhalter OI Miller ID Sullivan JK Lloyd JE Deanfield 1992 Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis Lancet 340 1111 5 1359209 10.1016/0140-6736(92)93147-F 1:STN:280:DyaK3s%2FmtFGhuw%3D%3D
    • (1992) Lancet , vol.340 , pp. 1111-5
    • Celermajer, D.S.1    Sorensen, K.E.2    Gooch, V.M.3    Spiegelhalter, D.J.4    Miller, O.I.5    Sullivan, I.D.6    Lloyd, J.K.7    Deanfield, J.E.8
  • 20
    • 52049087838 scopus 로고    scopus 로고
    • Modulation of angiotensin II-mediated hypertension and cardiac remodeling by lectin-like oxidized low-density lipoprotein receptor-1 deletion
    • 18645046 10.1161/HYPERTENSIONAHA.108.115287 1:CAS:528: DC%2BD1cXpvFKgs74%3D
    • C Hu A Dandapat L Sun MR Marwali N Inoue F Sugawara K Inoue Y Kawase K Jishage H Suzuki PL Hermonat T Sawamura JL Mehta 2008 Modulation of angiotensin II-mediated hypertension and cardiac remodeling by lectin-like oxidized low-density lipoprotein receptor-1 deletion Hypertension 52 556 62 18645046 10.1161/HYPERTENSIONAHA.108.115287 1:CAS:528:DC%2BD1cXpvFKgs74%3D
    • (2008) Hypertension , vol.52 , pp. 556-62
    • Hu, C.1    Dandapat, A.2    Sun, L.3    Marwali, M.R.4    Inoue, N.5    Sugawara, F.6    Inoue, K.7    Kawase, Y.8    Jishage, K.9    Suzuki, H.10    Hermonat, P.L.11    Sawamura, T.12    Mehta, J.L.13
  • 21
    • 68949205569 scopus 로고    scopus 로고
    • Deletion of LOX-1 attenuates renal injury following angiotensin II infusion
    • 19553911 10.1038/ki.2009.234 1:CAS:528:DC%2BD1MXhtVWiurjL
    • C Hu BY Kang J Megyesi GP Kaushal RL Safirstein JL Mehta 2009 Deletion of LOX-1 attenuates renal injury following angiotensin II infusion Kidney Int. 76 521 7 19553911 10.1038/ki.2009.234 1:CAS:528:DC%2BD1MXhtVWiurjL
    • (2009) Kidney Int. , vol.76 , pp. 521-7
    • Hu, C.1    Kang, B.Y.2    Megyesi, J.3    Kaushal, G.P.4    Safirstein, R.L.5    Mehta, J.L.6
  • 23
    • 0023785749 scopus 로고
    • Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone
    • 2841353 10.1172/JCI113621 1:CAS:528:DyaL1cXlsVGlsb0%3D
    • R Bolli BS Patel MO Jeroudi EK Lai PB McCay 1988 Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone J Clin Invest. 82 476 85 2841353 10.1172/JCI113621 1:CAS:528:DyaL1cXlsVGlsb0%3D
    • (1988) J Clin Invest. , vol.82 , pp. 476-85
    • Bolli, R.1    Patel, B.S.2    Jeroudi, M.O.3    Lai, E.K.4    McCay, P.B.5
  • 24
    • 0030026058 scopus 로고    scopus 로고
    • Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs
    • JZ Sun XL Tang SW Park Y Qiu JF Turrens R Bolli 1996 Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs J Clin Invest. 97 562 76 8567981 10.1172/JCI118449 1:CAS:528:DyaK28Xht1Ols70%3D (Pubitemid 26039424)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.2 , pp. 562-576
    • Sun, J.-Z.1    Tang, X.-L.2    Park, S.-W.3    Qiu, Y.4    Turrens, J.F.5    Bolli, R.6
  • 26
    • 0037454162 scopus 로고    scopus 로고
    • Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction
    • DOI 10.1016/S0735-1097(02)02966-2
    • D Li V Williams L Liu H Chen T Sawamura F Romeo JL Mehta 2003 Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction J Am Coll Cardiol 41 1048 55 12651056 10.1016/S0735-1097(02)02966-2 1:CAS:528:DC%2BD3sXislejsb8%3D (Pubitemid 36315552)
    • (2003) Journal of the American College of Cardiology , vol.41 , Issue.6 , pp. 1048-1055
    • Li, D.1    Williams, V.2    Liu, L.3    Chen, H.4    Sawamura, T.5    Romeo, F.6    Mehta, J.L.7
  • 28
    • 36649020178 scopus 로고    scopus 로고
    • LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfusion
    • DOI 10.1016/j.cardiores.2007.07.003, PII S0008636307003318
    • C Hu A Dandapat J Chen Y Fujita N Inoue Y Kawase K Jishage H Suzuki T Sawamura JL Mehta 2007 LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfusion Cardiovasc Res 76 292 302 17707356 10.1016/j.cardiores.2007.07.003 1:CAS:528:DC%2BD2sXhtFGrtLfJ (Pubitemid 350198599)
    • (2007) Cardiovascular Research , vol.76 , Issue.2 , pp. 292-302
    • Hu, C.1    Dandapat, A.2    Chen, J.3    Fujita, Y.4    Inoue, N.5    Kawase, Y.6    Jishage, K.-i.7    Suzuki, H.8    Sawamura, T.9    Mehta, J.L.10
  • 30
    • 25444501019 scopus 로고    scopus 로고
    • Adhesion molecule expression in fibroblasts: Alteration in fibroblast biology after transfection with LOX-1 plasmids
    • DOI 10.1161/01.HYP.0000179045.95915.b0
    • K Chen J Chen Y Liu J Xie D Li T Sawamura PL Hermonat JL Mehta 2005 Adhesion molecule expression in fibroblasts: alteration in fibroblast biology after transfection with LOX-1 plasmids Hypertension 46 622 7 16116044 10.1161/01.HYP.0000179045.95915.b0 1:CAS:528:DC%2BD2MXptVWrsrg%3D (Pubitemid 41376845)
    • (2005) Hypertension , vol.46 , Issue.3 , pp. 622-627
    • Chen, K.1    Chen, J.2    Liu, Y.3    Xie, J.4    Li, D.5    Sawamura, T.6    Hermonat, P.L.7    Mehta, J.L.8
  • 32
    • 21644465333 scopus 로고    scopus 로고
    • Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome a novel marker for early diagnosis
    • DOI 10.1161/CIRCULATIONAHA.104.468397
    • K Hayashida N Kume T Murase M Minami D Nakagawa T Inada M Tanaka A Ueda G Kominami H Kambara T Kimura T Kita 2005 Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: a novel marker for early diagnosis Circulation 112 812 8 16061745 10.1161/CIRCULATIONAHA.104.468397 1:CAS:528:DC%2BD2MXmvVKrtLg%3D (Pubitemid 41170066)
    • (2005) Circulation , vol.112 , Issue.6 , pp. 812-818
    • Hayashida, K.1    Kume, N.2    Murase, T.3    Minami, M.4    Nakagawa, D.5    Inada, T.6    Tanaka, M.7    Ueda, A.8    Kominami, G.9    Kambara, H.10    Kimura, T.11    Kita, T.12
  • 33
    • 77954527680 scopus 로고    scopus 로고
    • Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts prognosis after acute coronary syndrome-a pilot study
    • 20467154 10.1253/circj.CJ-09-0924 1:CAS:528:DC%2BC3cXpvFans70%3D
    • N Kume H Mitsuoka K Hayashida M Tanaka T Kita 2010 Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts prognosis after acute coronary syndrome-a pilot study Circ J 74 1399 404 20467154 10.1253/circj.CJ-09- 0924 1:CAS:528:DC%2BC3cXpvFans70%3D
    • (2010) Circ J , vol.74 , pp. 1399-404
    • Kume, N.1    Mitsuoka, H.2    Hayashida, K.3    Tanaka, M.4    Kita, T.5
  • 35
    • 34548086211 scopus 로고    scopus 로고
    • Modulation of ADP-induced platelet activation by aspirin and pravastatin: Role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling
    • DOI 10.1124/jpet.107.122853
    • MR Marwali CP Hu B Mohandas A Dandapat P Deonikar J Chen I Cawich T Sawamura M Kavdia JL Mehta 2007 Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling J Pharmacol Exp Ther 322 1324 32 17538005 10.1124/jpet.107.122853 1:CAS:528:DC%2BD2sXpslKrtLk%3D (Pubitemid 47295783)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.322 , Issue.3 , pp. 1324-1332
    • Marwali, M.R.1    Hu, C.-P.2    Mohandas, B.3    Dandapat, A.4    Deonikar, P.5    Chen, J.6    Cawich, I.7    Sawamura, T.8    Kavdia, M.9    Mehta, J.L.10
  • 36
    • 77958198213 scopus 로고    scopus 로고
    • Incidence, predictors and outcome of drug-eluting stent thrombosis in real-world practice
    • 20944183
    • M Blich T Zeidan-Shwiri S Petcherski A Osherov H Hammerman 2010 Incidence, predictors and outcome of drug-eluting stent thrombosis in real-world practice J Invasive Cardiol. 22 461 4 20944183
    • (2010) J Invasive Cardiol. , vol.22 , pp. 461-4
    • Blich, M.1    Zeidan-Shwiri, T.2    Petcherski, S.3    Osherov, A.4    Hammerman, H.5
  • 37
    • 79952645825 scopus 로고    scopus 로고
    • Pathobiology of stent thrombosis after drug-eluting stent implantation
    • 21208180 10.2174/138161210794454879 1:CAS:528:DC%2BC3MXjtVajtro%3D
    • M Vorpahl SK Yazdani M Nakano E Ladich FD Kolodgie AV Finn R Virmani 2010 Pathobiology of stent thrombosis after drug-eluting stent implantation Curr Pharm Des 16 4064 71 21208180 10.2174/138161210794454879 1:CAS:528: DC%2BC3MXjtVajtro%3D
    • (2010) Curr Pharm des , vol.16 , pp. 4064-71
    • Vorpahl, M.1    Yazdani, S.K.2    Nakano, M.3    Ladich, E.4    Kolodgie, F.D.5    Finn, A.V.6    Virmani, R.7
  • 39
    • 29144514436 scopus 로고    scopus 로고
    • Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model
    • DOI 10.1016/j.cardiores.2005.08.013, PII S0008636305004190
    • J Hinagata M Kakutani T Fujii T Naruko N Inoue Y Fujita JL Mehta M Ueda T Sawamura 2006 Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model Cardiovasc Res 69 263 71 16183045 10.1016/j.cardiores.2005.08.013 1:CAS:528:DC%2BD2MXhtlGisbzL (Pubitemid 41814827)
    • (2006) Cardiovascular Research , vol.69 , Issue.1 , pp. 263-271
    • Hinagata, J.-I.1    Kakutani, M.2    Fujii, T.3    Naruko, T.4    Inoue, N.5    Fujita, Y.6    Mehta, J.L.7    Ueda, M.8    Sawamura, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.