An active endocytosis pathway is required for the cytotoxic effects of glycosylated antitumor ether lipids

Anticancer Research

Volumn 31, Issue 11, 2011, Pages 3809-3818

  Samadder, Pranati ^a   Byun, Hoe Sup ^b   Bittman, Robert ^b   Arthur, Gilbert ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Cytotoxicity; Endocytosis; Glycosylated antitumor ether lipid; Mechanism of action; Methyl cyclodextrin

Indexed keywords

1 O HEXADECYL 2 O METHYL 3 O (2' (2 METHOXYBENZYLAMINO) 2' DEOXY BETA DEXTRO GLUCOPYRANOSYL) SN GLYCEROL; 1 O HEXADECYL 2 O METHYL 3 O (2' 2 CHLOROBENZYLAMINO) 2' DEOXY BETA DEXTRO GLUCOPYRANOSYL) SN GLYCEROL; 1 O HEXADECYL 2 O METHYL 3 O (2' 2 CYANOBENZYLAMINO) 2' DEOXY BETA DEXTRO GLUCOPYRANOSYL) SN GLYCEROL; 1 O HEXADECYL 2 O METHYL 3 O (2' 2 N,N DIMETHYLAMINOBENZYLAMINO) 2' DEOXY BETA DEXTRO GLUCOPYRANOSYL) SN GLYCEROL; 1 O HEXADECYL 2 O METHYL 3 O (2' AMINO 2' DEOXY BETA DEXTRO GLUCOPYRANOSYL) SN GLYCEROL; 1 O HEXADECYL 2 O METHYL 3 O (2' BENZYLAMINO) 2' DEOXY BETA DEXTRO GLUCOPYRANOSYL) SN GLYCEROL; ANTINEOPLASTIC AGENT; BENZYLAMINE DERIVATIVE; ETHER LIPID; METHYL BETA CYCLODEXTRIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL MATURATION; CELL MEMBRANE; CELL VACUOLE; CYTOTOXICITY; DIFFUSION; DRUG ACTIVITY; DRUG SYNTHESIS; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; HYDROPHOBICITY; INCUBATION TEMPERATURE; LYSOSOME; PKA; PRIORITY JOURNAL; PROTON TRANSPORT;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA-CYCLODEXTRINS; CELL PROLIFERATION; CELLS, CULTURED; ENDOCYTOSIS; GLYCOLIPIDS; GLYCOSYLATION; HUMANS; LYSOSOMES; MAP KINASE KINASE KINASE 5; MICE; MICE, KNOCKOUT; NEOPLASMS; VACUOLES;

EID: 83055179599     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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