Increased response to oxidative stress challenge in Graves' ophthalmopathy orbital fibroblasts

Molecular Vision

Volumn 17, Issue , 2011, Pages 2782-2788

  Tsai, Chieh Chih ^a,c   Wu, Shi Bei ^a,c   Cheng, Ching Yu ^a,c   Kao, Shu Ching ^a,c   Kau, Hui Chuan ^a,b,c   Lee, Shui Mei ^a,c   Wei, Yau Huei ^a,c,d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b KOO FOUNDATION SUN YAT SEN CANCER CENTER   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^d MACKAY MEDICAL COLLEGE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENDOCRINE OPHTHALMOPATHY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPID PEROXIDATION; MOLECULAR PATHOLOGY; ORBITAL FIBROBLAST; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANTIOXIDANTS; CASE-CONTROL STUDIES; CATALASE; CELLS, CULTURED; DEOXYGUANOSINE; DNA DAMAGE; FIBROBLASTS; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GRAVES OPHTHALMOPATHY; HUMANS; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALONDIALDEHYDE; ORBIT; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 83055178384     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Prabhakar BS, Bahn RS, Smith TJ. Current perspective on the pathogenesis of Graves' disease and ophthalmopathy. Endocr Rev 2003; 24:802-35. [PMID: 14671007]
2. Bahn RS. Graves' ophthalmopathy. N Engl J Med 2010; 362:726-38. [PMID: 20181974]
3. Smith TJ, Tsai CC, Shih MJ, Tsui S, Chen B, Han R, Naik V, King CS, Press C, Kamat S, Goldberg RA, Phipps RP, Douglas RS, Gianoukakis AG. Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy. Thyroid 2008; 18:983-8. [PMID: 18788919]
4. Bednarek J, Wysocki H, Sowinski J. Oxidative stress peripheral parameters in Graves' disease: the effect of methimazole treatment in patients with and without infiltrative ophthalmopathy. Clin Biochem 2005; 38:13-8. [PMID: 15607311]
5. Tsai CC, Cheng CY, Liu CY, Kao SC, Kau HC, Hsu WM, Wei YH. Oxidative stress in patients with Graves' Ophthalmopathy: Relationship between oxidative DNA damage and clinical evolution. Eye (Lond) 2009; 23:1725-30. [PMID: 18849914]
6. Tsai CC, Kao SC, Cheng CY, Kau HC, Hsu WM, Lee CF, Wei YH. Oxidative stress change by systemic corticosteroids treatment of patients with active Graves' ophthalmopathy. Arch Ophthalmol 2007; 125:1652-6. [PMID: 18071117]
7. Hondur A, Konuk O, Dincel AS, Bilgihan A, Unal M, Hasanreisoglu B. Oxidative stress and antioxidant activity in orbital fibroadipose tissue in Graves' ophthalmopathy. Curr Eye Res 2008; 33:421-7. [PMID: 18568878]
8. Tsai CC, Wu SB, Cheng CY, Kao SC, Kau HC, Chiou SH, Hsu WM, Wei YH. Increased oxidative DNA damage, lipid peroxidation, and reactive oxygen species in cultured orbital fibroblasts from patients with Graves' ophthalmopathy: evidence that oxidative stress has a role in this disorder. Eye (Lond) 2010; 24:1520-5. [PMID: 20300129]
9. Lu CY, Lee HC, Fahn HJ, Wei YH. Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin. Mutat Res 1999; 423:11-21. [PMID: 10029667]
10. Nociari MM, Shalev A, Benias P, Russo C. A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity. J Immunol Methods 1998; 213:157-67. [PMID: 9692848]
11. Kim HW, Murakami A, Williams MV, Ohigashi H. Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells. Carcinogenesis 2003; 24:235-41. [PMID: 12584172]
12. Lin PH, Lee SH, Su CP, Wei YH. Oxidative damage to mitochondrial DNA in atrial muscle of patients with atrial fibrillation. Free Radic Biol Med 2003; 35:1310-8. [PMID: 14607530]
13. Spitz DR, Oberley LW. An assay for superoxide dismutase activity in mammalian tissue homogenates. Anal Biochem 1989; 179:8-18. [PMID: 2547324]
14. Degl'Innocenti D. Rosati F, Iantomasi T, Vincenzini MT, Ramponi G. GSH system in relation to redox state in dystrophic skin fibroblasts. Biochimie 1999; 81:1025-9. [PMID: 10575357]
15. Smith TJ. Insights into the role of fibroblasts in human autoimmune diseases. Clin Exp Immunol 2005; 141:388-97. [PMID: 16045727]
16. Chwa M, Atilano SR, Hertzog D, Zheng H, Langberg J, Kim DW, Kenney MC. Hypersensitive response to oxidative stress in keratoconus corneal fibroblasts. Invest Ophthalmol Vis Sci 2008; 49:4361-9. [PMID: 18515575]
17. Werner SR, Prahalad AK, Yang J, Hock JM. RECQL4-deficient cells are hypersensitive to oxidative stress/damage: Insights for osteosarcoma prevalence and heterogeneity in Rothmund-Thomson syndrome. Biochem Biophys Res Commun 2006; 345:403-9. [PMID: 16678792]
18. Chen MP, Yang SH, Chou CH, Yang KC, Wu CC, Cheng YH, Lin FH. The chondroprotective effects of ferulic acid on hydrogen peroxide-stimulated chondrocytes: inhibition of hydrogen peroxide-induced pro-inflammatory cytokines and metalloproteinase gene expression at the mRNA level. Inflamm Res 2010; 59:587-95. [PMID: 20349328]
19. Smith TJ. Orbital fibroblasts exhibit a novel pattern of responses to proinflammatory cytokines: potential basis for the pathogenesis of thyroid-associated ophthalmopathy. Thyroid 2002; 12:197-203. [PMID: 11952039]
20. Burdon RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1995; 18:775-94. [PMID: 7750801]
21. Feldon SE, Park DJ, O'Loughlin CW, Nguyen VT, Landskroner-Eiger S, Chang D, Thatcher TH, Phipps RP. Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy. Invest Ophthalmol Vis Sci 2005; 46:3913-21. [PMID: 16249464]
22. Burch HB, Lahiri S, Bahn RS, Barnes S. Superoxide radical production stimulates retroocular fibroblast proliferation in Graves' ophthalmopathy. Exp Eye Res 1997; 65:311-6. [PMID: 9268599]
23. Burdon RH, Gill V, Alliangana D. Hydrogen peroxide in relation to proliferation and apoptosis in BHK-21 hamster fibroblasts. Free Radic Res 1996; 24:81-93. [PMID: 8845916]
24. Gurjala AN, Liu WR, Mogford JE, Procaccini PS, Mustoe TA. Age-dependent response of primary human dermal fibroblasts to oxidative stress: cell survival, pro-survival kinases, and entrance into cellular senescence. Wound Repair Regen 2005; 13:565-75. [PMID: 16283872]
25. Heufelder AE, Wenzel BE, Bahn RS. Methimazole and propylthiouracil inhibit the oxygen free radical-induced expression of a 72 kDa heat shock protein in Graves' retroocular fibroblasts. J Clin Endocrinol Metab 1992; 74:737-42. [PMID: 1532179]
26. Bouzas EA, Karadimas P, Mastorakos G, Koutras DA. Antioxidant agents in the treatment of Graves' ophthalmopathy. Am J Ophthalmol 2000; 129:618-22. [PMID: 10844053]
27. Murrell GA, Francis MJ, Bromley L. Modulation of fibroblast proliferation by oxygen free radicals. Biochem J 1990; 265:659-65. [PMID: 2154966]
28. Remacle J, Raes M, Toussaint O, Renard P, Rao G. Low levels of reactive oxygen species as modulators of cell function. Mutat Res 1995; 316:103-22. [PMID: 7862174]