Smart polymers: Innovations in novel drug delivery

International Journal of Drug Development and Research

Volumn 3, Issue 3, 2011, Pages 16-30

  Mahajan, Apoorva ^a   Aggarwal, Geeta ^a  

^a INSTITUTE OF NANO SCIENCE AND TECHNOLOGY   (India)

Author keywords

Novel drug delivery; pH sensitive polymers; Smart polymers; Temperature sensitive polymers

Indexed keywords

1 METHYL 2 PYRROLIDINONE; 3 AMINOPROPYLTRIETHOXYSILANE; 4 AMINOBENZENSULFONAMIDE DERIVATIVE; ALGINIC ACID; CARBOMER; CHITOSAN; DRUG VEHICLE; ELASTIN; EMULSIFYING AGENT; GLYCOFUROL; HUMAN SERUM ALBUMIN; LIPOSOME; MACROGOL; METHACRYLIC ACID; METHACRYLIC ACID METHYL ESTER; POLY(N ISOPROPYLACRYLAMIDE); POLY(N,N DIMETHYLAMINOETHYL METHACRYLAMIDE); POLYACID DERIVATIVE; POLYACRYLIC ACID; POLYBASE DERIVATIVE; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; POLYMETHACRYLIC ACID; POLYSULFONAMIDE DERIVATIVE; POLYVINYL ALCOHOL; SELF ASSEMBLED MONOLAYER; SMART POLYMER; TETRAGLYCOL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BIOCOMPATIBILITY; BIODEGRADABILITY; BIOTECHNOLOGY; CONTROLLED RELEASE FORMULATION; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG MECHANISM; ENZYME MECHANISM; ENZYME RELEASE; GENE THERAPY; GENETIC ENGINEERING; HUMAN; LIGHT; MICELLIZATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PH; PHASE TRANSITION; POLYMERIZATION; PROTEIN FOLDING; REVIEW; SUSTAINED DRUG RELEASE; TEMPERATURE; TISSUE ENGINEERING;

EID: 83055168214     PISSN: None     EISSN: 09759344     Source Type: Journal    
DOI: None     Document Type: Review

References (51)

1. Galaev IY, Mattiason B. Smart polymers and what they do in biotechnology and medicine. Trends Biotechnol. 1999; 17: 335-340.
2. Hoffmann AS, Stayton PS. Bioconjugates of smart polymers and proteins: synthesis and application. Pharmaceut Sci J. 2004; 207: 139-151.
3. Hoffmann AS. Bioconjugates of intelligent polymers and recognition proteins for use in diagnostics and affinity seperations. Clin Chem. 2000; 46: 1478-1486.
4. Hoffmann AS, Stayton PS, Murthy N. Design of smart polymers that can direct intracellular drug delivery. Polym Advan Technol. 2002; 13: 992-999
5. Hester JF, Olugebefola SC, Mayes AM. Preparation of pH-responsive polymer membranes by self organization. Membrane Sci J. 2002; 208: 375-388
6. Park SY, Bae YH. Novel pH sensitive polymers containing sulfonamide groups. Macromol Rapid Comm. 1999; 20: 269-273.
7. Samer M, Streich D, Meier W. pH-sensitivenanocontainers. Adv Mater. 2001; 13: 1649-1651
8. Nagasaki Y, Luol L, Tsuruta T, Kataoka K. Novel pH-sensitive microsphere processing a stable skin layer. Macromol Rapid Comm. 2001; 22: 1124-1127
9. Podual K, Doyle H, Peppas NA. Preparation and dynamic response of cationic copolymers containing glucose oxidase. Polymer J. 2000; 41: 3975-3983
10. Jones RAL. Biomimetic polymers: tough and smart. Nat Mater. 2004; 3: 209-210.
11. Stayton PS, El Sayed ME, Murthy N. Smart delivery systems for biomolecule therapeutics. Orthodontics and craniofacial research. 2005; 8: 219-225.
12. Yan L, zhu Q, Kenkare PU. Lower critical solution temperature of linear PNIPA obtained from a yukana potential chains. Appl Polym Sci J. 2007; 78: 1971-1976.
13. Jones MS. Effect of pH on the LCST of random copolymers of N-isopropylacrylamide and acrylic acid. Eur Polym J. 1999; 35: 795-801.
14. Cao YL, Ibarra C, Vacanti C. Preparation and use of thermoresponsive polymers. In: Morgan JR and Yarmush ML. (eds.) Tissue engineering: methods and protocols. Humana Press, Totowa 2006, pp 75-84.
15. Spohr R, Reber N. Thermal control of drug release by a responsive ion track membrane observed by radio tracer flow dialysis. Control Release J. 1988; 50: 1-11.
16. Okano T, Bae YH, Jacobs H, Kim SW. Thermally on-off switching polymers for drug permeation and drug release. Control Release J. 1990; 11: 225-265
17. Chen G, Hoffmann AS. Graft co-polymers that exhibit temperature induced phase transition over a wide range of pH. Nature J. 1995; 373: 49-52.
18. Gil ES, Hudson SM. Stimuli-responsive polymers and their bioconjugates. Prog Polym Sci. 2004; 29: 1173-1222.
19. Lou L, Kato M, Tsuruta T, Kataoka K, Nagasaki Y. Stimuli-sensitive polymer gels that stiffen upon swelling. Macromolecules J. 2000; 33: 4992-4994
20. Gonalez N, Elvira C, San Roman J. Novel dual- stimuli-responsive polymers derived from ethylpyrrolidine. Macromolecules J. 2005; 38: 9298-9303.
21. Jeong B, Gutowska A. Stimuli-responsiveness polymers and their biochemical applications. Trend Biotechnol. 2002; 20: 305-311.
22. Huang J, Wu. XY. Effects of pH, salt, surfactant and composition on phase transition of poly (NIPAm/ MAA) nanoparticles. Polym Sci J. 1999; 37: 2667-2676.
23. Kokufuta E, Zhang YQ, Tanaka T, Mamada A. Effects of surfectants on the phase-transition of polymer (N-iso-propylacrylamide) gel. Macromolecules J. 1993; 26: 1053-1059.
24. Higuchi T. Mechanism of sustained-action mechanism. Pharm Sci J. 1963; 52: 1145-1149
25. Singh S, Singh J. Controlled release of a model protein lyzozyme from phase sensitive smart polymer systems. Intl J Pharma. 2004; 271: 189-196.
26. Gan LH, Gan YY, Roshan Dean G. Poly (N-acrylol-N propylpiperazine): a new stimuli responsive polymer. Macromolecules J. 2000; 33: 7893-7897.
27. Stayton PS, Shimoboji T, Long C. Control of protein ligand recognition using a stimuli-responsive polymer. Nature J. 1995; 378: 472-475.
28. Nath N, Chilkoti A. Creating smart surfaces using stimuli-responsive polymers. Adv Mater. 2002; 14: 1243-1247.
29. Lupitskyy R, Roiter Y, Minko S, Tsitsilianis C. Smart polymer molecules to responsive nanostructured surfaces. Langmuir J. 2005; 21: 8591-8593.
30. Uhlmann P, Houbenov N, Stamm M, Minko S. surface functionalization by smart binary polymer brushes to tune physic-chemical characteristics at biointerfaces. E-polymers J. 2005; 75: 1-10.
31. Chourasis MK, Jain SK. Pharmaceutical approaches to colon targeted drug delivery systems. Pharmaceut Sci J. 2003; 6: 33-66.
32. Chourasis MK, Jain SK. Polysaccharides for colon targeted drug delivery. Drug Delivery. 2004; 11: 129-148.
33. Davaran S, Hanaee J, Khosrani A. Release of 5- amino salicylic acid from acrylic type polymeric prodrugs designed for colonic-specific drug delivery. Control Release J. 1999; 58: 279-287.
34. Zangmeister RA, Tarlov MJ. DNA displacement assay integrated into microfluidic channels. Anal Chem. 2004; 76: 3655-3659.
35. Harmon ME, Tang M, Frank CW. A microfluidic actuator based on thermoresponsive hydrogel. Polymer J. 2003; 44: 4547-4556.
36. Huber DL, Manginell RP, Samara MA, Kim B, Bunker BC. Programmed adsorption and release of proteins in a microfluidic device. Science J. 2003; 301: 352-354.
37. Cao X, Lai S, Lee LJ. Design of a self-regulated drug delivery device. Biomed Microdev. 2001; 3: 109-118
38. Godbey WT, Mikos AG. Recent progress in gene delivery using non-viral transfer complexes. Control Release J. 2001; 52: 142-150.
39. Borchard G. Chitosans for gene delivery. Adv Drug Deliv Rev. 2001; 52: 145-150.
40. Brahmin S, Narinesingh D, gniseppi-elie A. Bio- smart hydrogels: conjoined molecular recognition and signal transduction in biosensor fabrication and drug delivery. Biosens Bioelectron. 2002; 17: 973-981.
41. Sheppard NF, Lesho MJ, McNally P, Shaun Franco- macaro A. Microfabricated conductimetric pH sensor. Sen Actuat B. 1995; 28: 95-102.
42. Ruan C, Zeng K, Grimes CA. A mass-sensitive pH sensor based on a stimuli-responsive polymer. Anal Chim Acta. 2003; 497: 123-131.
43. Kikuchi A, Okano T. Nanostructured designs of biomedical materials: application of cell sheet engineering to functional regenerative tissues and organs. Control Release J. 2005; 101: 69-84.
44. Shimizu T, Yamato M, Kikuchin A, Okano T. Cell sheet engineering for myocardial tissue reconstruction. Biomaterial J. 2003; 24: 2309-2316.
45. Diamond AD, Hsu JT. Aqueous two phase systems for biomolecule separation. Adv Biochem Eng Biotechnol. 1992; 47: 89-135.
46. Scopes RK. Protein purification: principles and practice. New York: Springer. 1994; 24: 106-110
47. Mattiason B and Kaul R. Affinity precipitation. In: Ngo T. (eds.) Molecular interaction in bioseperations. Phenum Press, New York. 1993, pp 469-477.
48. Kukoi R, Morita S, Ota H, Umakoshi H. Protein refolding using stimuli-responsive polymer- modified aqueous two-phase systems. J Chromatogr B Biomed Sci Appl. 2000; 743: 215-223.
49. Chen YJ, Huang LW, Chin HC, Lin SC. Temperature-responsive polymer-assisted protein refolding. Enzyme Microb Technol. 2003; 32: 120-130.
50. Lee HJ. Protein drug oral delivery: The recent progress. Arch Phar Res. 2002; 25: 572-584.
51. Cleland JL, Daughterty A, Mrsny R. Emerging protein delivery methods. Curr Opin Biotech. 2001; 12: 212-219.