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Volumn 8, Issue 6, 2011, Pages 2398-2407

Therapeutic and cytotoxic effects of the novel antipsoriasis codrug, naproxyl-dithranol, on HaCaT cells

Author keywords

codrug; dithranol; inflammation; naproxen; prodrug; proliferation

Indexed keywords

ANTIPSORIASIS AGENT; CASPASE 3; CYCLINE; CYCLOOXYGENASE 2; DITHRANOL; KI 67 ANTIGEN; NAPROXEN; NAPROXYL DITHRANOL; UNCLASSIFIED DRUG;

EID: 82955240648     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200327k     Document Type: Article
Times cited : (13)

References (29)
  • 1
    • 84861483299 scopus 로고    scopus 로고
    • National Psoriasis Foundation. About psoriasis. (19 Jun)
    • National Psoriasis Foundation. About psoriasis. http://www.psoriasis.org/ about/psoriasis/ (19 Jun 2011).
    • (2011)
  • 2
    • 36048945952 scopus 로고    scopus 로고
    • Psoriasis: epidemiology
    • DOI 10.1016/j.clindermatol.2007.08.007, PII S0738081X07001514
    • Gudjonsson, J. E.; Elder, J. T. Psoriasis: epidemiology Clin. Dermatol. 2007, 25 (6) 535-546 (Pubitemid 350087600)
    • (2007) Clinics in Dermatology , vol.25 , Issue.6 , pp. 535-546
    • Gudjonsson, J.E.1    Elder, J.T.2
  • 3
    • 32644435765 scopus 로고    scopus 로고
    • The treatment of psoriasis and psoriatic arthritis: An interdisciplinary approach
    • Gordon, K. B.; Ruderman, E. M. The treatment of psoriasis and psoriatic arthritis: an interdisciplinary approach J. Am. Acad. Dermatol. 2006, 54 (3) S86-91
    • (2006) J. Am. Acad. Dermatol. , vol.54 , Issue.3 , pp. 86-91
    • Gordon, K.B.1    Ruderman, E.M.2
  • 5
    • 34447547568 scopus 로고    scopus 로고
    • Current and future management of psoriasis
    • DOI 10.1016/S0140-6736(07)61129-5, PII S0140673607611295
    • Menter, A.; Griffiths, C. E. M. Current and future management of psoriasis Lancet 2007, 370 (9583) 272-84 (Pubitemid 47071926)
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 272-284
    • Menter, A.1    Griffiths, C.E.2
  • 8
    • 78651323059 scopus 로고    scopus 로고
    • Topical delivery of a naproxen-dithranol co-drug: In vitro skin penetration, permeation, and staining
    • Lau, W. M.; White, A. W.; Heard, C. M. Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining Pharm. Res. 2010, 27 (12) 2734-42
    • (2010) Pharm. Res. , vol.27 , Issue.12 , pp. 2734-42
    • Lau, W.M.1    White, A.W.2    Heard, C.M.3
  • 11
    • 33749337643 scopus 로고    scopus 로고
    • Evaluation of the anti-proliferative properties of selected psoriasis-treating Chinese medicines on cultured HaCaT cells
    • DOI 10.1016/j.jep.2006.04.023, PII S037887410600225X
    • Tse, W. P.; Che, C. T.; Liu, K.; Lin, Z. X. Evaluation of the anti-proliferative properties of selected psoriasis-treating Chinese medicines on cultured HaCaT cells J. Ethnopharmacol. 2006, 108 (1) 133-41 (Pubitemid 44498993)
    • (2006) Journal of Ethnopharmacology , vol.108 , Issue.1 , pp. 133-141
    • Tse, W.-P.1    Che, C.-T.2    Liu, K.3    Lin, Z.-X.4
  • 12
    • 0043125910 scopus 로고    scopus 로고
    • Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay
    • DOI 10.1290/1543-706X(2003)039<0036:COAEOE>2.0.CO;2
    • Pol, A.; Bergers, M.; Schalkwijk, J. Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay In Vitro Cell. Dev. Biol.: Anim. 2003, 39 (1-2) 36-42 (Pubitemid 36944607)
    • (2003) In Vitro Cellular and Developmental Biology - Animal , vol.39 , Issue.1-2 , pp. 36-42
    • Pol, A.1    Bergers, M.2    Schalkwijk, J.3
  • 13
    • 0035490537 scopus 로고    scopus 로고
    • Detection of telomerase activity in psoriasis lesional skin and correlation with Ki-67 expression and suppression by retinoic acid
    • Jang, H. S.; Oh, C. K.; Jo, J. H.; Kim, Y. S.; Kwon, K. S. Detection of telomerase activity in psoriasis lesional skin and correlation with Ki-67 expression and suppression by retinoic acid J. Korean Med. Sci. 2001, 16 (5) 623-9
    • (2001) J. Korean Med. Sci. , vol.16 , Issue.5 , pp. 623-9
    • Jang, H.S.1    Oh, C.K.2    Jo, J.H.3    Kim, Y.S.4    Kwon, K.S.5
  • 15
    • 0030815980 scopus 로고    scopus 로고
    • Differential proliferation of endothelial cells and keratinocytes in psoriasis and spongiotic dermatitis
    • DOI 10.1111/j.1600-0560.1997.tb00804.x
    • Sweet, W. L.; Smoller, B. R. Differential proliferation of endothelial cells and keratinocytes in psoriasis and spongiotic dermatitis J. Cutaneous Pathol. 1997, 24 (6) 356-63 (Pubitemid 27312016)
    • (1997) Journal of Cutaneous Pathology , vol.24 , Issue.6 , pp. 356-363
    • Sweet, W.L.1    Smoller, B.R.2
  • 16
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
    • DOI 10.1084/jem.193.5.607
    • Hernandez, G. L.; Volpert, O. V.; Iniguez, M. A.; Lorenzo, E.; Martinez-Martinez, S.; Grau, R.; Fresno, M.; Redondo, J. M. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2 J. Exp. Med. 2001, 193 (5) 607-20 (Pubitemid 32539557)
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.5 , pp. 607-620
    • Hernandez, G.L.1    Volpert, O.V.2    Iniguez, M.A.3    Lorenzo, E.4    Martinez-Martinez, S.5    Grau, R.6    Fresno, M.7    Redondo, J.M.8
  • 17
    • 33644558369 scopus 로고    scopus 로고
    • Co-localization of COX-2, CYP4F8, and mPGES-1 in epidermis with prominent expression of CYP4F8 mRNA in psoriatic lesions
    • Stark, K.; Torma, H.; Oliw, E. H. Co-localization of COX-2, CYP4F8, and mPGES-1 in epidermis with prominent expression of CYP4F8 mRNA in psoriatic lesions Prostaglandins Other Lipid Mediators 2006, 79 (1-2) 114-25
    • (2006) Prostaglandins Other Lipid Mediators , vol.79 , Issue.1-2 , pp. 114-25
    • Stark, K.1    Torma, H.2    Oliw, E.H.3
  • 18
    • 0033031331 scopus 로고    scopus 로고
    • COX-2 inhibitors
    • DOI 10.1016/S0140-6736(98)12154-2
    • Hawkey, C. J. COX-2 inhibitors Lancet 1999, 353 (9149) 307-14 (Pubitemid 29089366)
    • (1999) Lancet , vol.353 , Issue.9149 , pp. 307-314
    • Hawkey, C.J.1
  • 19
    • 0029932386 scopus 로고    scopus 로고
    • Cyclooxygenases in human and mouse skin and cultured human keratinocytes: Association of COX-2 expression with human keratinocyte differentiation
    • DOI 10.1006/excr.1996.0113
    • Leong, J.; Hughes-Fulford, M.; Rakhlin, N.; Habib, A.; Maclouf, J.; Goldyne, M. E. Cyclooxygenases in human and mouse skin and cultured human keratinocytes: association of COX-2 expression with human keratinocyte differentiation Exp. Cell Res. 1996, 224 (1) 79-87 (Pubitemid 26116890)
    • (1996) Experimental Cell Research , vol.224 , Issue.1 , pp. 79-87
    • Leong, J.1    Hughes-Fulford, M.2    Rakhlin, N.3    Habib, A.4    Maclouf, J.5    Goldyne, M.E.6
  • 21
    • 0035282655 scopus 로고    scopus 로고
    • Comparative effects of indomethacin on cell proliferation and cell cycle progression in tumor cells grown in vitro and in vivo
    • DOI 10.1016/S0006-2952(00)00578-5, PII S0006295200005785
    • Eli, Y.; Przedecki, F.; Levin, G.; Kariv, N. A.; Raz, A. Comparative effects of indomethacin on cell proliferation and cell cycle progression in tumor cells grown in vitro and in vivo Biochem. Pharmacol. 2001, 61 (5) 565-71 (Pubitemid 32178490)
    • (2001) Biochemical Pharmacology , vol.61 , Issue.5 , pp. 565-571
    • Eli, Y.1    Przedecki, F.2    Levin, G.3    Kariv, N.4    Raz, A.5
  • 22
    • 0034717224 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and apoptosis in the gastrointestinal tract: Potential role of the pentose phosphate pathways
    • DOI 10.1016/S0014-2999(00)00237-5, PII S0014299900002375
    • Porter, S. N.; Howarth, G. S.; Butler, R. N. Non-steroidal anti-inflammatory drugs and apoptosis in the gastrointestinal tract: potential role of the pentose phosphate pathways Eur. J. Pharmacol. 2000, 397 (1) 1-9 (Pubitemid 30323804)
    • (2000) European Journal of Pharmacology , vol.397 , Issue.1 , pp. 1-9
    • Porter, S.N.1    Howarth, G.S.2    Butler, R.N.3
  • 23
    • 0030812790 scopus 로고    scopus 로고
    • Dithranol
    • DOI 10.1016/S0738-081X(97)00019-9, PII S0738081X97000199
    • Mahrle, G. Dithranol Clin. Dermatol. 1997, 15 (5) 723-37 (Pubitemid 27411475)
    • (1997) Clinics in Dermatology , vol.15 , Issue.5 , pp. 723-737
    • Mahrle, G.1
  • 26
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. M. Caspases: the executioners of apoptosis Biochem. J. 1997, 326, 1-16 (Pubitemid 27386911)
    • (1997) Biochemical Journal , vol.326 , Issue.1 , pp. 1-16
    • Cohen, G.M.1
  • 27
    • 0041328573 scopus 로고    scopus 로고
    • Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells
    • DOI 10.1042/BJ20030280
    • Hughes, A.; Smith, N. I.; Wallace, H. M. Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells Biochem. J. 2003, 374 (2) 481-8 (Pubitemid 37094107)
    • (2003) Biochemical Journal , vol.374 , Issue.2 , pp. 481-488
    • Hughes, A.1    Smith, N.I.2    Wallace, H.M.3
  • 28
    • 0036174687 scopus 로고    scopus 로고
    • Disparate effects of non-steroidal anti-inflammatory drugs on apoptosis in guinea-pig gastric mucous cells: Inhibition of basal apoptosis by diclofenac
    • Ashton, M.; Hanson, P. J. Disparate effects of non-steroidal anti-inflammatory drugs on apoptosis in guinea-pig gastric mucous cells: inhibition of basal apoptosis by diclofenac Br. J. Pharmacol. 2002, 135 (2) 407-16 (Pubitemid 34151173)
    • (2002) British Journal of Pharmacology , vol.135 , Issue.2 , pp. 407-416
    • Ashton, M.1    Hanson, P.J.2
  • 29
    • 20444447706 scopus 로고    scopus 로고
    • The anti-psoriatic drug anthralin accumulates in keratinocyte mitochondria, dissipates mitochondrial membrane potential, and induces apoptosis through a pathway dependent on respiratory competent mitochondria
    • DOI 10.1096/fj.04-2664fje
    • McGill, A.; Frank, A.; Emmett, N.; Leech, S. N.; Turnbull, D. M.; Birch-Machin, M. A.; Reynolds, N. J. The antipsoriatic drug anthralin accumulates in keratinocyte mitochondria, dissipates mitochondrial membrane potential, and induces apoptosis through a pathway dependent on respiratory competent mitochondria FASEB J. 2005, 19 (8) 1012-4 (Pubitemid 40827735)
    • (2005) FASEB Journal , vol.19 , Issue.8 , pp. 1012-1014
    • McGill, A.1    Frank, A.2    Emmett, N.3    Turnbull, D.M.4    Birch-Machin, M.A.5    Reynolds, N.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.