Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures

Journal of Neuro-Oncology

Volumn 105, Issue 2, 2011, Pages 241-251

  Xu, Jihong ^a   Sampath, Deepa ^a   Lang, Frederick F ^a   Prabhu, Sujit ^a   Rao, Ganesh ^a   Fuller, Gregory N ^a   Liu, Yuanfang ^a   Puduvalli, Vinay K ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Apoptosis; Cell cycle arrest; Histone deacetylase inhibitors; Malignant glioma; Organotypic slice cultures

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; PROTEIN P21; PROTEIN P53; VORINOSTAT;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRAIN SLICE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE REGULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVITY; EX VIVO STUDY; FLOW CYTOMETRY; GLIOMA CELL; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ACETYLATION; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN B1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FLOW CYTOMETRY; G2 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; HYDROXAMIC ACIDS; IN SITU NICK-END LABELING; ORGAN CULTURE TECHNIQUES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 82955237437     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-011-0604-7     Document Type: Article

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