Nodal metastasis from locally advanced esophageal cancer: How neoadjuvant therapy modifies their frequency and distribution

Annals of Surgical Oncology

Volumn 18, Issue 13, 2011, Pages 3743-3754

  Castoro, Carlo ^a   Scarpa, Marco ^a   Cagol, Matteo ^a   Ruol, Alberto ^b   Cavallin, Francesco ^a   Alfieri, Rita ^a   Zanchettin, Gianpietro ^b   Rugge, Massimo ^b   Ancona, Ermanno ^a,b  

^a VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; TAXANE DERIVATIVE;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CHEMORADIOTHERAPY; CONTINUOUS INFUSION; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS CARCINOMA; HUMAN; LOWER ESOPHAGUS SPHINCTER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CHEMOTHERAPY, ADJUVANT; CISPLATIN; COMBINED MODALITY THERAPY; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; ESOPHAGOGASTRIC JUNCTION; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; PROGNOSIS; PROSPECTIVE STUDIES; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 82955233875     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-011-1753-9     Document Type: Article

References (35)

1. CG Peyre JA Hagen SR DeMeester NK Altorki E Ancona SM Griffin, et al. 2008 The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection Ann Surg. 248 549 556 18936567 10.1097/SLA.0b013e3181904f3c
2. N Altorki D Skinner 2001 Should en bloc esophagectomy be the standard of care for esophageal carcinoma? Ann Surg. 234 581 587 11685019 10.1097/00000658-200111000-00001 1:STN:280:DC%2BD3MngvFyltQ%3D%3D (Pubitemid 33041759)
3. JB Hulscher JW van Sandick AG de Boer BP Wijnhoven JG Tijssen P Fockens, et al. 2002 Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus N Engl J Med. 347 1662 1669 12444180 10.1056/NEJMoa022343 (Pubitemid 35340784)
4. AM Koenig KL Prenzel D Bogoevski EF Yekebas M Bubenheim L Faithova, et al. 2008 Strong impact of micrometastatic tumor cell load in patients with esophageal carcinoma Ann Surg Oncol. 16 454 462 19015923 10.1245/s10434-008- 0169-7
5. SC Malaisrie B Untch GV Aranha N Mohideen A Hantel J Pickleman 2004 Neoadjuvant chemoradiotherapy for locally advanced esophageal cancer Experience at a single institution Arch Surg. 139 532 539 15136354 10.1001/archsurg.139.5. 532 (Pubitemid 38585753)
6. V Gebski B Burmeister BM Smithers K Foo J Zalcberg J Simes, et al. 2007 Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis Lancet Oncol. 8 226 234 17329193 10.1016/S1470-2045(07)70039-6 1:CAS:528:DC%2BD2sXisVCqs78%3D (Pubitemid 46291702)
7. C Mariette JP Triboulet 2005 Is preoperative chemoradiation effective in treatment of oesophageal carcinoma? Lancet Oncol. 6 635 637 16129363 10.1016/S1470-2045(05)70295-3 1:STN:280:DC%2BD2Mvmt1CmsA%3D%3D (Pubitemid 41222742)
8. C Mariette G Piessen A Lamblin X Mirabel A Adenis JP Triboulet 2006 Impact of preoperative radiochemotherapy on postoperative course and survival in patients with locally advanced squamous cell oesophageal carcinoma Br J Surg. 93 1077 1083 16779882 10.1002/bjs.5358 1:STN:280:DC%2BD28rhs1Wmtw%3D%3D (Pubitemid 44343504)
9. JV Reynolds C Muldoon D Hollywood N Ravi S Rowley K O'Byrne, et al. 2007 Long-term outcomes following neoadjuvant chemoradiotherapy for esophageal cancer Ann Surg. 245 707 716 17457163 10.1097/01.sla.0000254367.15810.38 (Pubitemid 46684100)
10. NK Veeramachaneni JB Zoole PA Decker JB Putnam BF Meyers 2008 Lymph node analysis in esophageal resection: American College of Surgeons Oncology Group Z0060 Trial Ann Thorac Surg. 86 418 421 18640307 10.1016/j.athoracsur.2008.04. 043 (Pubitemid 351978043)
11. SM Dresner PJ Lamb MK Bennett N Hayes SM Griffin 2001 The pattern of metastatic lymph node dissemination from adenocarcinoma of the esophagogastric junction Surgery. 129 103 109 11150040 10.1067/msy.2001.110024 1:STN:280:DC%2BD3M7ht1Shuw%3D%3D (Pubitemid 32099263)
12. C Van de Ven P De Leyn W Coosemans D Van Raemdonck T Lerut 1999 Three-field lymphadenectomy and pattern of lymph node spread in T3 adenocarcinoma of the distal esophagus and the gastro-esophageal junction Eur J Cardiothorac Surg. 15 769 773 10431857 10.1016/S1010-7940(99)00122-0 (Pubitemid 29331950)
13. H Akiyama M Tsurumaru T Kawamura Y Ono 1981 Principles of surgical treatment for carcinoma of the esophagus: analysis of lymph node involvement Ann Surg. 194 438 446 7283505 10.1097/00000658-198110000-00007 1:STN:280: DyaL38%2Fit1GgsA%3D%3D
14. H Akiyama M Tsurumaru H Udagawa J Kajiyama 1994 Radical lymph node dissection for cancer of the thoracic esophagus Ann Surg. 220 364 372 8092902 10.1097/00000658-199409000-00012 1:STN:280:DyaK2cznvFyluw%3D%3D
15. N Altorki M Kent C Ferrara J Port 2002 Three-field lymph nodes dissection for squamous cell and adenocarcinoma of the esophagus Ann Surg. 236 177 183 12170022 10.1097/00000658-200208000-00005 (Pubitemid 34809536)
16. PJ Lamb SM Griffin AD Burt J Lloyd D Karat N Hayes 2005 Sentinel node biopsy to evaluate the metastatic dissemination of oesophageal adenocarcinoma Br J Surg. 92 60 67 15584066 10.1002/bjs.4693 1:STN:280:DC%2BD2M%2Fhs1ehtA%3D%3D (Pubitemid 40144196)
17. M Burian HJ Stein A Sendler M Piert J Nahrig M Feith, et al. 2004 Sentinel node detection in Barrett's and cardia cancer Ann Surg Oncol. 11 255S 258S 15023763
18. BA Grotenhuis BPL Wijnhoven R van Marion H van Dekken WC Hop HW Tilanus, et al. 2009 The sentinel node concept in adenocarcinomas of the distal esophagus and gastroesophageal junction J Thorac Cardiovasc Surg. 138 608 612 19698844 10.1016/j.jtcvs.2008.11.061
19. A Pennathur O Awais JD Luketich 2010 Technique of minimally invasive Ivor Lewis esophagectomy Ann Thorac Surg. 89 S2159 S2162 20494002 10.1016/j.athoracsur.2010.03.069
20. MB Orringer B Marshall AC Chang J Lee A Pickens CL Lau 2007 Two thousand transhiatal esophagectomies: changing trends, lessons learned Ann Surg. 246 363 372 17717440 10.1097/SLA.0b013e31814697f2 discussion 372-4
21. Sobin L, Wittekind C. UICC: TNM Classification of Malignant Tumors. 6th ed. New York: Wiley, 2002.
22. A Ruol G Portale C Castoro S Merigliano F Cavallin G Battaglia, et al. 2007 Management of esophageal cancer in patients aged over 80 years Eur J Cardiothorac Surg. 32 445 448 17643999 10.1016/j.ejcts.2007.06.014 (Pubitemid 47223742)
23. M Cagol A Ruol C Castoro R Alfieri S Michieletto E Ancona 2009 Prophylactic thoracic duct mass ligation prevents chylothorax after transthoracic esophagectomy for cancer World J Surg. 33 1684 1686 19533219 10.1007/s00268-009-0094-3
24. A Holscher W Schroder E Bollschweiler K Beckurts P Schneider 2003 How safe is high intrathoracic esophagogastrostomy? Chirurgie. 74 726 733 10.1007/s00104-003-0649-z 1:STN:280:DC%2BD3szptVemsA%3D%3D (Pubitemid 38270145)
25. E Ancona A Ruol S Santi S Merigliano VC Sileni H Koussis, et al. 2001 Only pathologic complete response to neoadjuvant chemotherapy improves significantly the long term survival of patients with resectable esophageal squamous cell carcinoma: final report of a randomized, controlled trial of preoperative chemotherapy versus surgery alone Cancer. 91 2165 2174 11391598 10.1002/1097-0142(20010601)91:11<2165::AID-CNCR1245>3.0.CO;2-H 1:STN:280:DC%2BD3MzhvFeitA%3D%3D (Pubitemid 32476382)
26. AP Barbour M Jones M Gonen DC Gotley J Thomas DB Thomson, et al. 2008 Refining esophageal cancer staging after neoadjuvant therapy: importance of treatment response Ann Surg Oncol. 15 2894 2902 18663531 10.1245/s10434-008- 0084-y
27. DP Kelsen R Ginsberg TF Pajak DG Sheahan L Gunderson J Mortimer, et al. 1998 Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer N Engl J Med. 339 1979 1984 9869669 10.1056/ NEJM199812313392704 1:STN:280:DyaK1M%2FnslCjsg%3D%3D (Pubitemid 29024130)
28. S Law M Fok S Chow K Chu J Wong 1997 Preoperative chemotherapy versus surgical therapy alone for squamous cell carcinoma of the esophagus: a prospective randomized trial J Thorac Cardiovasc Surg. 114 210 217 9270638 10.1016/S0022-5223(97)70147-8 1:STN:280:DyaK2svhs1Krug%3D%3D (Pubitemid 27364211)
29. AA Forastiere RF Heitmiller L Kleinberg 1997 Multimodality therapy for esophageal cancer Chest 112 suppl 195S 200S 9337287 10.1378/chest.112.4- Supplement.195S 1:STN:280:DyaK2svnslahtg%3D%3D (Pubitemid 27441079)
30. T Lehnert 1999 Multimodal therapy for squamous carcinoma of the oesophagus Br J Surg. 86 727 739 10383570 10.1046/j.1365-2168.1999.01152.x 1:STN:280:DyaK1Mzhs1agsg%3D%3D (Pubitemid 29271938)
31. P Sutton P Clark 2000 Neo-adjuvant treatment for oesophageal cancer GI Cancer. 3 231 238
32. JI Geh AM Crellin R Glynne-Jones 2001 Preoperative (neoadjuvant) chemoradiotherapy in oesophageal cancer Br J Surg. 88 338 356 11260097 10.1046/j.1365-2168.2001.01670.x 1:STN:280:DC%2BD3M7mtVaqsA%3D%3D (Pubitemid 32238694)
33. U Fumagalli 1996 Resective surgery for cancer of the thoracic esophagus: results of a consensus conference held at the VIth World Congress of the International Society for Diseases of the Esophagus Dis Esophagus. 9 S30 S38
34. SM Lagarde JB Reitsma FJW ten Kate ORC Busch H Obertop AH Zwinderman, et al. 2008 Predicting individual survival after potentially curative esophagectomy for adenocarcinoma of the esophagus or gastroesophageal junction Ann Surg. 248 1006 1013 19092345 10.1097/SLA.0b013e318190a0a2
35. H Kato Y Tachimori H Watanabe T Iizuka S Terui M Itabashi, et al. 1991 Lymph nodes metastasis in thoracic esophageal carcinoma J Surg Oncol. 48 106 111 1921395 10.1002/jso.2930480207 1:STN:280:DyaK38%2Fhs1CksQ%3D%3D