-
1
-
-
0038649988
-
Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
-
DOI 10.1161/01.CIR.0000072771.11429.83
-
Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation. 2003;107:2908-2913. (Pubitemid 36736631)
-
(2003)
Circulation
, vol.107
, Issue.23
, pp. 2908-2913
-
-
Gurbel, P.A.1
Bliden, K.P.2
Hiatt, B.L.3
O'Connor, C.M.4
-
2
-
-
0032800250
-
Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel
-
Geiger J, Brich J, Honig-Liedl P, Eigenthaler M, Schanzenbacher P, Herbert JM, Walter U. Specific impairment of human platelet p2y(ac) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. Arterioscler Thromb Vasc Biol. 1999;19:2007-2011. (Pubitemid 29379936)
-
(1999)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.19
, Issue.8
, pp. 2007-2011
-
-
Geiger, J.1
Brich, J.2
Honig-Liedl, P.3
Eigenthaler, M.4
Schanzenbacher, P.5
Herbert, J.M.6
Walter, U.7
-
3
-
-
77953911457
-
Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate
-
Bonello L, Tantry US, Marcucci R, Blindt R, Angiolillo DJ, Becker R, Bhatt DL, Cattaneo M, Collet JP, Cuisset T, Gachet C, Montalescot G, Jennings LK, Kereiakes D, Sibbing D, Trenk D, Van Werkum JW, Paganelli F, Price MJ, Waksman R, Gurbel PA. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J Am Coll Cardiol. 2010;56:919-933.
-
(2010)
J Am Coll Cardiol.
, vol.56
, pp. 919-933
-
-
Bonello, L.1
Tantry, U.S.2
Marcucci, R.3
Blindt, R.4
Angiolillo, D.J.5
Becker, R.6
Bhatt, D.L.7
Cattaneo, M.8
Collet, J.P.9
Cuisset, T.10
Gachet, C.11
Montalescot, G.12
Jennings, L.K.13
Kereiakes, D.14
Sibbing, D.15
Trenk, D.16
Van Werkum, J.W.17
Paganelli, F.18
Price, M.J.19
Waksman, R.20
Gurbel, P.A.21
more..
-
4
-
-
74749097435
-
Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement
-
Sibbing D, Schulz S, Braun S, Morath T, Stegherr J, Mehilli J, Schomig A, von Beckerath N, Kastrati A. Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement. J Thromb Haemost. 2010;8:250-256.
-
(2010)
J Thromb Haemost.
, vol.8
, pp. 250-256
-
-
Sibbing, D.1
Schulz, S.2
Braun, S.3
Morath, T.4
Stegherr, J.5
Mehilli, J.6
Schomig, A.7
Von Beckerath, N.8
Kastrati, A.9
-
5
-
-
77953191080
-
Platelet function testing and risk of bleeding complications
-
Ferreiro JL, Sibbing D, Angiolillo DJ. Platelet function testing and risk of bleeding complications. Thromb Haemost. 2010;103:1128-1135.
-
(2010)
Thromb Haemost
, vol.103
, pp. 1128-1135
-
-
Ferreiro, J.L.1
Sibbing, D.2
Angiolillo, D.J.3
-
7
-
-
73149119363
-
Identification of the human cytochrome p450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
-
Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A. Identification of the human cytochrome p450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos. 2010;38:92-99.
-
(2010)
Drug Metab Dispos.
, vol.38
, pp. 92-99
-
-
Kazui, M.1
Nishiya, Y.2
Ishizuka, T.3
Hagihara, K.4
Farid, N.A.5
Okazaki, O.6
Ikeda, T.7
Kurihara, A.8
-
8
-
-
69249219296
-
Association of cytochrome p450 2c19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
Shuldiner AR, O'Connell JR, Bliden KP, Gandhi A, Ryan K, Horenstein RB, Damcott CM, Pakyz R, Tantry US, Gibson Q, Pollin TI, Post W, Parsa A, Mitchell BD, Faraday N, Herzog W, Gurbel PA. Association of cytochrome p450 2c19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA. 2009;302:849-857.
-
(2009)
JAMA
, vol.302
, pp. 849-857
-
-
Shuldiner, A.R.1
O'Connell, J.R.2
Bliden, K.P.3
Gandhi, A.4
Ryan, K.5
Horenstein, R.B.6
Damcott, C.M.7
Pakyz, R.8
Tantry, U.S.9
Gibson, Q.10
Pollin, T.I.11
Post, W.12
Parsa, A.13
Mitchell, B.D.14
Faraday, N.15
Herzog, W.16
Gurbel, P.A.17
-
9
-
-
77955416969
-
Isolated and interactive impact of common cyp2c19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy
-
Sibbing D, Gebhard D, Koch W, Braun S, Stegherr J, Morath T, Von Beckerath N, Mehilli J, Schomig A, Schuster T, Kastrati A. Isolated and interactive impact of common cyp2c19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy. J Thromb Haemost. 2010;8: 1685-1693.
-
(2010)
J Thromb Haemost.
, vol.8
, pp. 1685-1693
-
-
Sibbing, D.1
Gebhard, D.2
Koch, W.3
Braun, S.4
Stegherr, J.5
Morath, T.6
Von Beckerath, N.7
Mehilli, J.8
Schomig, A.9
Schuster, T.10
Kastrati, A.11
-
10
-
-
33749339075
-
Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
-
DOI 10.1182/blood-2006-04-013052
-
Hulot JS, Bura A, Villard E, Azizi M, Remones V, Goyenvalle C, Aiach M, Lechat P, Gaussem P. Cytochrome p450 2c19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood. 2006;108:2244-2247. (Pubitemid 44497506)
-
(2006)
Blood
, vol.108
, Issue.7
, pp. 2244-2247
-
-
Hulot, J.-S.1
Bura, A.2
Villard, E.3
Azizi, M.4
Remones, V.5
Goyenvalle, C.6
Aiach, M.7
Lechat, P.8
Gaussem, P.9
-
11
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias W, Braunwald E, Sabatine MS. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med. 2009; 360:354-362.
-
(2009)
N Engl J Med.
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
Walker, J.R.7
Antman, E.M.8
Macias, W.9
Braunwald, E.10
Sabatine, M.S.11
-
12
-
-
58249135635
-
Cytochrome p450 2c19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
-
Collet JP, Hulot JS, Pena A, Villard E, Esteve JB, Silvain J, Payot L, Brugier D, Cayla G, Beygui F, Bensimon G, Funck-Brentano C, Montalescot G. Cytochrome p450 2c19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet. 2009;373:309-317.
-
(2009)
Lancet
, vol.373
, pp. 309-317
-
-
Collet, J.P.1
Hulot, J.S.2
Pena, A.3
Villard, E.4
Esteve, J.B.5
Silvain, J.6
Payot, L.7
Brugier, D.8
Cayla, G.9
Beygui, F.10
Bensimon, G.11
Funck-Brentano, C.12
Montalescot, G.13
-
13
-
-
65249145201
-
Cytochrome p450 2c19 lossof- function polymorphism and stent thrombosis following percutaneous coronary intervention
-
Sibbing D, Stegherr J, Latz W, Koch W, Mehilli J, Dorrler K, Morath T, Schomig A, Kastrati A, von Beckerath N. Cytochrome p450 2c19 lossof- function polymorphism and stent thrombosis following percutaneous coronary intervention. Eur Heart J. 2009;30:916-922.
-
(2009)
Eur Heart J.
, vol.30
, pp. 916-922
-
-
Sibbing, D.1
Stegherr, J.2
Latz, W.3
Koch, W.4
Mehilli, J.5
Dorrler, K.6
Morath, T.7
Schomig, A.8
Kastrati, A.9
Von Beckerath, N.10
-
14
-
-
61349191612
-
Relation of cytochrome p450 2c19 loss-of-function polymorphism to occurrence of drugeluting coronary stent thrombosis
-
Giusti B, Gori AM, Marcucci R, Saracini C, Sestini I, Paniccia R, Buonamici P, Antoniucci D, Abbate R, Gensini GF. Relation of cytochrome p450 2c19 loss-of-function polymorphism to occurrence of drugeluting coronary stent thrombosis. Am J Cardiol. 2009;103:806-811.
-
(2009)
Am J Cardiol.
, vol.103
, pp. 806-811
-
-
Giusti, B.1
Gori, A.M.2
Marcucci, R.3
Saracini, C.4
Sestini, I.5
Paniccia, R.6
Buonamici, P.7
Antoniucci, D.8
Abbate, R.9
Gensini, G.F.10
-
15
-
-
78049326068
-
Reduced-function cyp2c19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
-
Mega JL, Simon T, Collet JP, Anderson JL, Antman EM, Bliden K, Cannon CP, Danchin N, Giusti B, Gurbel P, Horne BD, Hulot JS, Kastrati A, Montalescot G, Neumann FJ, Shen L, Sibbing D, Steg PG, Trenk D, Wiviott SD, Sabatine MS. Reduced-function cyp2c19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA. 2010;304:1821-1830.
-
(2010)
JAMA
, vol.304
, pp. 1821-1830
-
-
Mega, J.L.1
Simon, T.2
Collet, J.P.3
Anderson, J.L.4
Antman, E.M.5
Bliden, K.6
Cannon, C.P.7
Danchin, N.8
Giusti, B.9
Gurbel, P.10
Horne, B.D.11
Hulot, J.S.12
Kastrati, A.13
Montalescot, G.14
Neumann, F.J.15
Shen, L.16
Sibbing, D.17
Steg, P.G.18
Trenk, D.19
Wiviott, S.D.20
Sabatine, M.S.21
more..
-
16
-
-
77958100874
-
Effect of cyp2c19 and abcb1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
-
Wallentin L, James S, Storey RF, Armstrong M, Barratt BJ, Horrow J, Husted S, Katus H, Steg PG, Shah SH, Becker RC. Effect of cyp2c19 and abcb1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet. 2010;376:1320-1328.
-
(2010)
Lancet
, vol.376
, pp. 1320-1328
-
-
Wallentin, L.1
James, S.2
Storey, R.F.3
Armstrong, M.4
Barratt, B.J.5
Horrow, J.6
Husted, S.7
Katus, H.8
Steg, P.G.9
Shah, S.H.10
Becker, R.C.11
-
17
-
-
76349098199
-
Cytochrome 2c19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
-
Sibbing D, Koch W, Gebhard D, Schuster T, Braun S, Stegherr J, Morath T, Schomig A, von Beckerath N, Kastrati A. Cytochrome 2c19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation. 2010;121:512-518.
-
(2010)
Circulation
, vol.121
, pp. 512-518
-
-
Sibbing, D.1
Koch, W.2
Gebhard, D.3
Schuster, T.4
Braun, S.5
Stegherr, J.6
Morath, T.7
Schomig, A.8
Von Beckerath, N.9
Kastrati, A.10
-
18
-
-
1642453779
-
Contribution of Hepatic Cytochrome P450 3A4 Metabolic Activity to the Phenomenon of Clopidogrel Resistance
-
DOI 10.1161/01.CIR.0000112378.09325.F9
-
Lau WC, Gurbel PA, Watkins PB, Neer CJ, Hopp AS, Carville DG, Guyer KE, Tait AR, Bates ER. Contribution of hepatic cytochrome p450 3a4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation. 2004;109:166-171. (Pubitemid 38114134)
-
(2004)
Circulation
, vol.109
, Issue.2
, pp. 166-171
-
-
Lau, W.C.1
Gurbel, P.A.2
Watkins, P.B.3
Neer, C.J.4
Hopp, A.S.5
Carville, D.G.M.6
Guyer, K.E.7
Tait, A.R.8
Bates, E.R.9
-
19
-
-
77953896604
-
Cardiovascular risk in clopidogreltreated patients according to cytochrome p450 2c19* 2 loss-of-function allele or proton pump inhibitor coadministration: A systematic meta-analysis
-
Hulot JS, Collet JP, Silvain J, Pena A, Bellemain-Appaix A, Barthelemy O, Cayla G, Beygui F, Montalescot G. Cardiovascular risk in clopidogreltreated patients according to cytochrome p450 2c19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis. J Am Coll Cardiol. 2010;56:134-143.
-
(2010)
J Am Coll Cardiol.
, vol.56
, pp. 134-143
-
-
Hulot, J.S.1
Collet, J.P.2
Silvain, J.3
Pena, A.4
Bellemain-Appaix, A.5
Barthelemy, O.6
Cayla, G.7
Beygui, F.8
Montalescot, G.9
-
20
-
-
58749090547
-
Genetic determinants of response to clopidogrel and cardiovascular events
-
Simon T, Verstuyft C, Mary-Krause M, Quteineh L, Drouet E, Meneveau N, Steg PG, Ferrieres J, Danchin N, Becquemont L. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360:363-375.
-
(2009)
N Engl J Med.
, vol.360
, pp. 363-375
-
-
Simon, T.1
Verstuyft, C.2
Mary-Krause, M.3
Quteineh, L.4
Drouet, E.5
Meneveau, N.6
Steg, P.G.7
Ferrieres, J.8
Danchin, N.9
Becquemont, L.10
-
21
-
-
43049179414
-
Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents
-
DOI 10.1016/j.jacc.2007.12.056, PII S0735109708008656
-
Trenk D, Hochholzer W, Fromm MF, Chialda LE, Pahl A, Valina CM, Stratz C, Schmiebusch P, Bestehorn HP, Buttner HJ, Neumann FJ. Cytochrome p450 2c19 681g>a polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents. J Am Coll Cardiol. 2008;51:1925-1934. (Pubitemid 351636443)
-
(2008)
Journal of the American College of Cardiology
, vol.51
, Issue.20
, pp. 1925-1934
-
-
Trenk, D.1
Hochholzer, W.2
Fromm, M.F.3
Chialda, L.-E.4
Pahl, A.5
Valina, C.M.6
Stratz, C.7
Schmiebusch, P.8
Bestehorn, H.-P.9
Buttner, H.J.10
Neumann, F.-J.11
-
22
-
-
77957792195
-
Cyp2c19*2 and cyp2c9*3 alleles are associated with stent thrombosis: A case-control study
-
Harmsze AM, van Werkum JW, Ten Berg JM, Zwart B, Bouman HJ, Breet NJ, van't Hof AW, Ruven HJ, Hackeng CM, Klungel OH, de Boer A, Deneer VH. Cyp2c19*2 and cyp2c9*3 alleles are associated with stent thrombosis: a case-control study. Eur Heart J. 2010;31:3046-3053.
-
(2010)
Eur Heart J.
, vol.31
, pp. 3046-3053
-
-
Harmsze, A.M.1
Van Werkum, J.W.2
Ten Berg, J.M.3
Zwart, B.4
Bouman, H.J.5
Breet, N.J.6
Van't Hof, A.W.7
Ruven, H.J.8
Hackeng, C.M.9
Klungel, O.H.10
De Boer, A.11
Deneer, V.H.12
-
23
-
-
78049433100
-
Effects of cyp2c19 genotype on outcomes of clopidogrel treatment
-
Pare G, Mehta SR, Yusuf S, Anand SS, Connolly SJ, Hirsh J, Simonsen K, Bhatt DL, Fox KA, Eikelboom JW. Effects of cyp2c19 genotype on outcomes of clopidogrel treatment. N Engl J Med. 2010;363:1704-1714.
-
(2010)
N Engl J Med.
, vol.363
, pp. 1704-1714
-
-
Pare, G.1
Mehta, S.R.2
Yusuf, S.3
Anand, S.S.4
Connolly, S.J.5
Hirsh, J.6
Simonsen, K.7
Bhatt, D.L.8
Fox, K.A.9
Eikelboom, J.W.10
-
24
-
-
79960012663
-
No association of paraoxonase-1 q192r genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting
-
Sibbing D, Koch W, Massberg S, Byrne RA, Mehilli J, Schulz S, Mayer K, Bernlochner I, Schomig A, Kastrati A. No association of paraoxonase-1 q192r genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting. Eur Heart J. 2011;32: 1605-1613.
-
(2011)
Eur Heart J.
, vol.32
, pp. 1605-1613
-
-
Sibbing, D.1
Koch, W.2
Massberg, S.3
Byrne, R.A.4
Mehilli, J.5
Schulz, S.6
Mayer, K.7
Bernlochner, I.8
Schomig, A.9
Kastrati, A.10
-
25
-
-
79952435294
-
The relation between cyp2c19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy
-
Gurbel PA, Shuldiner AR, Bliden KP, Ryan K, Pakyz RE, Tantry US. The relation between cyp2c19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy. Am Heart J. 2011;161: 598-604.
-
(2011)
Am Heart J.
, vol.161
, pp. 598-604
-
-
Gurbel, P.A.1
Shuldiner, A.R.2
Bliden, K.P.3
Ryan, K.4
Pakyz, R.E.5
Tantry, U.S.6
-
26
-
-
30344457586
-
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
-
DOI 10.1016/j.clpt.2005.10.002, PII S0009923605004613
-
Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, Ingelman-Sundberg M. A common novel cyp2c19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther. 2006;79:103-113. (Pubitemid 43069582)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.79
, Issue.1
, pp. 103-113
-
-
Sim, S.C.1
Risinger, C.2
Dahl, M.-L.3
Aklillu, E.4
Christensen, M.5
Bertilsson, L.6
Ingelman-Sundberg, M.7
-
27
-
-
77956353400
-
Protective effect of the cyp2c19*17 polymorphism with increased activation of clopidogrel on cardiovascular events
-
Tiroch KA, Sibbing D, Koch W, Roosen-Runge T, Mehilli J, Schomig A, Kastrati A. Protective effect of the cyp2c19*17 polymorphism with increased activation of clopidogrel on cardiovascular events. Am Heart J. 2010;160:506-512.
-
(2010)
Am Heart J.
, vol.160
, pp. 506-512
-
-
Tiroch, K.A.1
Sibbing, D.2
Koch, W.3
Roosen-Runge, T.4
Mehilli, J.5
Schomig, A.6
Kastrati, A.7
-
28
-
-
67949120411
-
The cyp2c19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome
-
Frere C, Cuisset T, Gaborit B, Alessi MC, Hulot JS. The cyp2c19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome. J Thromb Haemost. 2009; 7:1409-1411.
-
(2009)
J Thromb Haemost.
, vol.7
, pp. 1409-1411
-
-
Frere, C.1
Cuisset, T.2
Gaborit, B.3
Alessi, M.C.4
Hulot, J.S.5
-
29
-
-
79951785678
-
First analysis of the relation between cyp2c19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: The onset/offset and respond genotype studies
-
Tantry US, Bliden KP, Wei C, Storey RF, Armstrong M, Butler K, Gurbel PA. First analysis of the relation between cyp2c19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the onset/offset and respond genotype studies. Circ Cardiovasc Genet. 2010; 3:556-566.
-
(2010)
Circ Cardiovasc Genet.
, vol.3
, pp. 556-566
-
-
Tantry, U.S.1
Bliden, K.P.2
Wei, C.3
Storey, R.F.4
Armstrong, M.5
Butler, K.6
Gurbel, P.A.7
-
30
-
-
79957673659
-
The influence of cyp2c19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of p2y(12) inhibitors
-
Price MJ, Tantry US, Gurbel PA. The influence of cyp2c19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of p2y(12) inhibitors. Rev Cardiovasc Med. 2011; 12:1-12.
-
(2011)
Rev Cardiovasc Med.
, vol.12
, pp. 1-12
-
-
Price, M.J.1
Tantry, U.S.2
Gurbel, P.A.3
-
31
-
-
33751080762
-
Impact of P-glycoprotein on clopidogrel absorption
-
DOI 10.1016/j.clpt.2006.07.007, PII S0009923606003018
-
Taubert D, von Beckerath N, Grimberg G, Lazar A, Jung N, Goeser T, Kastrati A, Schomig A, Schomig E. Impact of p-glycoprotein on clopidogrel absorption. Clin Pharmacol Ther. 2006;80:486-501. (Pubitemid 44767878)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.5
, pp. 486-501
-
-
Taubert, D.1
Von Beckerath, N.2
Grimberg, G.3
Lazar, A.4
Jung, N.5
Goeser, T.6
Kastrati, A.7
Schomig, A.8
Schomig, E.9
-
32
-
-
77958105401
-
Genetic variants in abcb1 and cyp2c19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the Triton-TIMI 38 trial: A pharmacogenetic analysis
-
Mega JL, Close SL, Wiviott SD, Shen L, Walker JR, Simon T, Antman EM, Braunwald E, Sabatine MS. Genetic variants in abcb1 and cyp2c19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the Triton-TIMI 38 trial: a pharmacogenetic analysis. Lancet. 2010;376:1312-1319.
-
(2010)
Lancet
, vol.376
, pp. 1312-1319
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Walker, J.R.5
Simon, T.6
Antman, E.M.7
Braunwald, E.8
Sabatine, M.S.9
-
33
-
-
78651239845
-
Paraoxonase-1 is a major determinant of clopidogrel efficacy
-
Bouman HJ, Schomig E, van Werkum JW, Velder J, Hackeng CM, Hirschhauser C, Waldmann C, Schmalz HG, Ten Berg JM, Taubert D. Paraoxonase-1 is a major determinant of clopidogrel efficacy. Nat Med. 2011;17:110-116.
-
(2011)
Nat Med.
, vol.17
, pp. 110-116
-
-
Bouman, H.J.1
Schomig, E.2
Van Werkum, J.W.3
Velder, J.4
Hackeng, C.M.5
Hirschhauser, C.6
Waldmann, C.7
Schmalz, H.G.8
Ten Berg, J.M.9
Taubert, D.10
-
34
-
-
77952591958
-
Impact of cytochrome p450 2c19 loss-offunction polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement
-
Hochholzer W, Trenk D, Fromm MF, Valina CM, Stratz C, Bestehorn HP, Buttner HJ, Neumann FJ. Impact of cytochrome p450 2c19 loss-offunction polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement. J Am Coll Cardiol. 2010;55:2427-2434.
-
(2010)
J Am Coll Cardiol.
, vol.55
, pp. 2427-2434
-
-
Hochholzer, W.1
Trenk, D.2
Fromm, M.F.3
Valina, C.M.4
Stratz, C.5
Bestehorn, H.P.6
Buttner, H.J.7
Neumann, F.J.8
-
35
-
-
66349133650
-
Cytochrome p450 genetic polymorphisms and the response to prasugrel: Relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes
-
Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias WL, Braunwald E, Sabatine MS. Cytochrome p450 genetic polymorphisms and the response to prasugrel: Relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes. Circulation. 2009;119:2553-2560.
-
(2009)
Circulation
, vol.119
, pp. 2553-2560
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
Walker, J.R.7
Antman, E.M.8
Macias, W.L.9
Braunwald, E.10
Sabatine, M.S.11
-
36
-
-
79952598836
-
Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The gravitas randomized trial
-
Price MJ, Berger PB, Teirstein PS, Tanguay JF, Angiolillo DJ, Spriggs D, Puri S, Robbins M, Garratt KN, Bertrand OF, Stillablower ME, Aragon JR, Kandzari DE, Stinis CT, Lee MS, Manoukian SV, Cannon CP, Schork NJ, Topol EJ. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The gravitas randomized trial. JAMA. 2011;305:1097-1105.
-
(2011)
JAMA
, vol.305
, pp. 1097-1105
-
-
Price, M.J.1
Berger, P.B.2
Teirstein, P.S.3
Tanguay, J.F.4
Angiolillo, D.J.5
Spriggs, D.6
Puri, S.7
Robbins, M.8
Garratt, K.N.9
Bertrand, O.F.10
Stillablower, M.E.11
Aragon, J.R.12
Kandzari, D.E.13
Stinis, C.T.14
Lee, M.S.15
Manoukian, S.V.16
Cannon, C.P.17
Schork, N.J.18
Topol, E.J.19
-
37
-
-
36148983750
-
Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
DOI 10.1056/NEJMoa0706482
-
Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, Neumann FJ, Ardissino D, De Servi S, Murphy SA, Riesmeyer J, Weerakkody G, Gibson CM, Antman EM. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357:2001-2015. (Pubitemid 350106708)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.20
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Montalescot, G.4
Ruzyllo, W.5
Gottlieb, S.6
Neumann, F.-J.7
Ardissino, D.8
De Servi, S.9
Murphy, S.A.10
Riesmeyer, J.11
Weerakkody, G.12
Gibson, C.M.13
Antman, E.M.14
-
38
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, Held C, Horrow J, Husted S, James S, Katus H, Mahaffey KW, Scirica BM, Skene A, Steg PG, Storey RF, Harrington RA, Freij A, Thorsen M. Ticagrelor 512 Circ Cardiovasc Interv October 2011 Downloaded from circinterventions.ahajournals.org by Gerrit Jan KRAMER on December 7, 2011 versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2009;361:1045-1057.
-
(2009)
N Engl J Med.
, vol.361
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
Cannon, C.P.4
Emanuelsson, H.5
Held, C.6
Horrow, J.7
Husted, S.8
James, S.9
Katus, H.10
Mahaffey, K.W.11
Scirica, B.M.12
Skene, A.13
Steg, P.G.14
Storey, R.F.15
Harrington, R.A.16
Freij, A.17
Thorsen, M.18
-
39
-
-
36348943475
-
Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
-
DOI 10.1111/j.1538-7836.2007.02775.x
-
Brandt JT, Close SL, Iturria SJ, Payne CD, Farid NA, Ernest CS II, Lachno DR, Salazar D, Winters KJ. Common polymorphisms of cyp2c19 and cyp2c9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost. 2007;5:2429-2436. (Pubitemid 350154353)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.12
, pp. 2429-2436
-
-
Brandt, J.T.1
Close, S.L.2
Iturria, S.J.3
Payne, C.D.4
Farid, N.A.5
Ernest, C.S.6
Lachno, D.R.7
Salazar, D.8
Winters, K.J.9
-
40
-
-
77956353401
-
Prognostic significance of high on-clopidogrel platelet reactivity after percutaneous coronary intervention: Systematic review and meta-analysis
-
Aradi D, Komocsi A, Vorobcsuk A, Rideg O, Tokes-Fuzesi M, Magyarlaki T, Horvath IG, Serebruany VL. Prognostic significance of high on-clopidogrel platelet reactivity after percutaneous coronary intervention: systematic review and meta-analysis. Am Heart J. 2010;160: 543-551.
-
(2010)
Am Heart J.
, vol.160
, pp. 543-551
-
-
Aradi, D.1
Komocsi, A.2
Vorobcsuk, A.3
Rideg, O.4
Tokes-Fuzesi, M.5
Magyarlaki, T.6
Horvath, I.G.7
Serebruany, V.L.8
-
41
-
-
77955603691
-
Platelet aggregation and its association with stent thrombosis and bleeding in clopidogrel-treated patients: Initial evidence of a therapeutic window
-
Sibbing D, Steinhubl SR, Schulz S, Schomig A, Kastrati A. Platelet aggregation and its association with stent thrombosis and bleeding in clopidogrel-treated patients: initial evidence of a therapeutic window. J Am Coll Cardiol. 2010;56:317-318.
-
(2010)
J Am Coll Cardiol.
, vol.56
, pp. 317-318
-
-
Sibbing, D.1
Steinhubl, S.R.2
Schulz, S.3
Schomig, A.4
Kastrati, A.5
-
42
-
-
77958571929
-
Pilot study of the antiplatelet effect of increased clopidogrel maintenance dosing and its relationship to cyp2c19 genotype in patients with high on-treatment reactivity
-
Barker CM, Murray SS, Teirstein PS, Kandzari DE, Topol EJ, Price MJ. Pilot study of the antiplatelet effect of increased clopidogrel maintenance dosing and its relationship to cyp2c19 genotype in patients with high on-treatment reactivity. J Am Coll Cardiol Cardiovasc Interv. 2010;3: 1001-1007.
-
(2010)
J Am Coll Cardiol Cardiovasc Interv.
, vol.3
, pp. 1001-1007
-
-
Barker, C.M.1
Murray, S.S.2
Teirstein, P.S.3
Kandzari, D.E.4
Topol, E.J.5
Price, M.J.6
-
43
-
-
44349185490
-
Residual platelet activity is increased in clopidogrel- and ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease
-
DOI 10.1136/hrt.2006.100891
-
Geisler T, Kapp M, Gohring-Frischholz K, Daub K, Dosch C, Bigalke B, Langer H, Herdeg C, Gawaz M. Residual platelet activity is increased in clopidogrel- and ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease. Heart. 2008;94:743-747. (Pubitemid 351744692)
-
(2008)
Heart
, vol.94
, Issue.6
, pp. 743-747
-
-
Geisler, T.1
Kapp, M.2
Gohring-Frischholz, K.3
Daub, K.4
Dosch, C.5
Bigalke, B.6
Langer, H.7
Herdeg, C.8
Gawaz, M.9
-
44
-
-
79955764408
-
A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines
-
2011 ACCF/AHA focused update of the guidelines for the management of patients with unstable angina/ non-ST-elevation myocardial infarction (updating the 2007 guideline)
-
Wright RS, Anderson JL, Adams CD, Bridges CR, Casey DE Jr, Ettinger SM, Fesmire FM, Ganiats TG, Jneid H, Lincoff AM, Peterson ED, Philippides GJ, Theroux P, Wenger NK, Zidar JP, Jacobs AK. 2011 ACCF/AHA focused update of the guidelines for the management of patients with unstable angina/ non-ST-elevation myocardial infarction (updating the 2007 guideline): a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation. 2011;123:2022-2060.
-
(2011)
Circulation
, vol.123
, pp. 2022-2060
-
-
Wright, R.S.1
Anderson, J.L.2
Adams, C.D.3
Bridges, C.R.4
Casey Jr., D.E.5
Ettinger, S.M.6
Fesmire, F.M.7
Ganiats, T.G.8
Jneid, H.9
Lincoff, A.M.10
Peterson, E.D.11
Philippides, G.J.12
Theroux, P.13
Wenger, N.K.14
Zidar, J.P.15
Jacobs, A.K.16
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