Is the fibronectin-aggrecan complex present in cervical disk disease?

PM and R

Volumn 3, Issue 11, 2011, Pages 1030-1034

  Gajendran, Varun K ^a   Reuter, Merrill W ^b   Golish, S Raymond ^a   Hanna, Lewis S ^c   Scuderi, Gaetano J ^a  

^a STANFORD UNIVERSITY   (United States)

^b Private Practice   (United States)

^c Cytonics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; CYTOKINE; FIBRONECTIN; GAMMA INTERFERON; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN;

ADULT; AGED; ARTICLE; ASPIRATION; CERVICAL SPINE; CERVICOBRACHIAL NEURALGIA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INTERVERTEBRAL DISK HERNIA; INTERVERTEBRAL DISKECTOMY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL DENSITY; PH; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ADULT; AGED; AGGRECANS; BIOLOGICAL MARKERS; CERVICAL VERTEBRAE; FEMALE; FIBRONECTINS; FOLLOW-UP STUDIES; HUMANS; INTERVERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISC DISPLACEMENT; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 82955226118     PISSN: 19341482     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pmrj.2011.07.003     Document Type: Article

References (12)

1. Kang J.D., Georgescu H.I., McIntyre-Larkin L., et al. Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2. Spine (Phila Pa 1976) 1996, 21:271-277.
2. Kang J.D., Georgescu H.I., McIntyre-Larkin L., Stefanovic-Racic M., Evans C.H. Herniated cervical intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2. Spine (Phila Pa 1976) 1995, 20:2373-2378.
3. Kang J.D., Stefanovic-Racic M., McIntyre L.A., Georgescu H.I., Evans C.H. Toward a biochemical understanding of human intervertebral disc degeneration and herniation. Contributions of nitric oxide, interleukins, prostaglandin E2, and matrix metalloproteinases. Spine (Phila Pa 1976) 1997, 22:1065-1073.
4. Scuderi G.J., Woolf N., Dent K., et al. Identification of a complex between fibronectin and aggrecan G3 domain in synovial fluid of patients with painful meniscal pathology. Clin Biochem 2010, 43:808-814.
5. Scuderi G.J., Golish S.R., Cook F.F., Cuellar J.M., Bowser R.P., Hanna L.S. Identification of a novel fibronectin-aggrecan complex in the synovial fluid of knees with painful meniscal injury. J Bone Joint Surg Am 2011, 93:336-340.
6. Golish S., Hanna L.S., Bowser R.P., Montesano P.X., Carragee E.J., Scuderi G.J. Outcome of lumbar epidural steroid injection is predicted by assay of a complex of fibronectin and aggrecan from epidural lavage. Spine (Phila Pa 1976) 2011, 36:1464-1469.
7. Scuderi G.J., Brusovanik G.V., Golish S.R., et al. A critical evaluation of discography in patients with lumbar intervertebral disc disease. Spine J 2008, 8:624-629.
8. de Jager W., te Velthuis H., Prakken B.J., Kuis W., Rijkers G.T. Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells. Clin Diagn Lab Immunol 2003, 10:133-139.
9. Cuellar J.M., Scuderi G.J., Cuellar V.G., Golish S.R., Yeomans D.C. Diagnostic utility of cytokine biomarkers in the evaluation of acute knee pain. J Bone Joint Surg Am 2009, 91:2313-2320.
10. Stout A. Discography. Phys Med Rehabil Clin N Am 2010, 21:859-867.
11. Scuderi G.J., Brusovanik G.V., Anderson D.G., et al. Cytokine assay of the epidural space lavage in patients with lumbar intervertebral disk herniation and radiculopathy. J Spinal Disord Tech 2006, 19:266-269.
12. Nassr A., Lee J.Y., Bashir R.S., et al. Does incorrect level needle localization during anterior cervical discectomy and fusion lead to accelerated disc degeneration?. Spine (Phila Pa 1976) 2009, 34:189-192.