Preventive and protective effects of turkish propolis on H 2O 2-induced DNA damage in foreskin fibroblast cell lines

Acta Biologica Hungarica

Volumn 62, Issue 4, 2011, Pages 388-396

  Aliyazicioglu, Yuksel ^a   Demir, S ^a   Turan, I ^b   Cakiroglu, Tugba ^a   Akalin, I ^a   Deger, O ^a   Bedir, A ^c  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

^b GUMUSHANE UNIVERSITY   (Turkey)

^c ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

anti genotoxicity; comet assay; foreskin fibroblast cells; Propolis

Indexed keywords

HYDROGEN PEROXIDE; PROPOLIS; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; FIBROBLAST; NONHUMAN; PREPUCE;

CELL LINE; DNA DAMAGE; FIBROBLASTS; FORESKIN; HUMANS; HYDROGEN PEROXIDE; MALE; PROPOLIS;

EID: 82955225087     PISSN: 02365383     EISSN: 1588256X     Source Type: Journal    
DOI: 10.1556/ABiol.62.2011.4.5     Document Type: Article

References (32)

1. Aliyazicioglu, Y., Deger, O., Ovali, E., Barlak, Y., Hosver, I., Tekelioglu, Y., Karahan, S. C. (2005) effects of turkish pollen and propolis extracts on respiratory burst for k-562 cell lines. Int. Immunopharmacol. 5, 1652-1657. (Pubitemid 41024864)
2. Bankova, V., Castro, S. L., Marcucci, M. C. (2000) Propolis: recent advances in chemistry and plant origin. Apidologie 31, 3-15. (Pubitemid 30106313)
3. Banskota, A. H., Tezuka, Y., Adnyana, I. K., Midorikawa, K., Matsushige, K., Message, D., Huertas, A. A., Kadota, S. (2000) cytotoxic, hepatoprotective, and free radical scavenging effects of propolis from brazil, Peru, the nederland and china. J. Ethnopharmacol. 72, 239-246.
4. Bazo, A. P., Rodriguez, M. A. M., Sforcin, J. M., Camargo, J. L. V., Riberio, L. R., Salvadori, D. M. F. (2002) Protective action of propolis on the rat colon carcinogenesis. Teratog. Carcinog. Mutagen. 22, 183-194. (Pubitemid 34437646)
5. Burdock, G. A. (1998) review of the biplogical properties and toxicity of bee propolis. Food Chem. Toxicol. 36, 347-363. (Pubitemid 28255348)
6. Cakiroglu, T. (2010) Investigation of solubility in different solvents of Turkish propolis. ktu health institute, msc thesis, trabzon, turkey. (in turkish).
7. Campos, M. G., Cunha, A., Markham, K. R. (1997) bee pollen: composition, properties, and applications. in: mizrahi a, lensky Y. (eds), Bee products (properties, applications, and apitherapy). Plenum Press, new York and london, pp. 93-100.
8. Davis, P. H. (1965-1985) Flora of Turkey and the East Aegean Islands. edinburgh university Press, edinburgh, vols. 1-9.
9. De Flora, S. (1998) mechanism of inhibitors of mutagenesis and carcinogenesis. Mutat. Res. 402, 151-158.
10. Frenkel, K., Wei, H., Bhimani, R., Ye, J., Zadunaisky, J. A., Huang, M. T., Ferraro, T., Conney, A. H., Grunberger, D. (1993) inhibition of tumor mediated-process in mouse skin and bovine lens by caf-feic acid phenethyl ester. Cancer Res. 53, 1255-1261. (Pubitemid 23097098)
11. Halliwel, B. (2007) dietary polyphenols: good, bad, or indifferent for your health? Cardiovasc. Res. 73, 341-347.
12. Hartmann, A., Speit, G. (1997) the contribution of cytotoxicity of edible mushroom in a histidine-independent bacterial test system. Food Chem. Toxicol. 29, 159-165.
13. Hazra, T. K., Das, A., Das, S., Choudury, S., Kow, Y. V., Roy, R. (2007) oxidative dna damage repair in mammalian cells: a new perspective. DNA Repair 6, 470-480. (Pubitemid 46357682)
14. Jaruga, P., Dizdaroglu, M. (1996) repair of products of oxidative dna base damage in human cells. Nucleic Acids Res. 24, 1389-1394. (Pubitemid 26118969)
15. Joenge, H. (1989) genetic toxicology of oxygen. Mutat. Res. 219, 193-208.
16. Kimoto, T., Arai, S., Kohguchi, M. B. S., Aga, M., Nomura, Y., Micallef, M. J., Kurimoto, M., Mito, K. (1998) apoptosis and suppression of tumor growth by artepellin c extracted from brazilian propolis. Cancer Detect. Prev. 22, 506-515. (Pubitemid 28537432)
17. Kroyer, G., Hegedus, N. (2002) evaluation of bioactive properties of pollen extracts as functional dietary food supplement. Innov. Food Sci. Emerg. Technol. 2, 171-174.
18. Lee, R. F., Steinert, S. (2003) Use of the single cell gel electrophoresis/comet assay for detecting DNA damage in aquatic (marine and fresh water) animals. Mutat. Res. 544, 43-64. (Pubitemid 36897769)
19. Mirzoeva, O. K., Calder, P. C. (1996) the effect of propolis and its components on eicosanoid production during the infammatory response. Prostaglandins Leukot. Essent. Fatty Acids 55, 441-449. (Pubitemid 27014134)
20. Moreno, M. I. N., Isla, M. I., Sampietro, A. R., Vattuone, M. A. (2000) comparison of the free radical scavenging activity of propolis from several regions of argentina. J. Ethnopharmacol. 71, 109-114. (Pubitemid 30440659)
21. Munari, C. C., Alves, J. M., Bastos, J. K., Tavares, D. C. (2010) evaluation of the genotoxic and antigenotoxic potential of baccharis dracunculifolia extract on v79 cells by the comet assay. J. Appl. Toxicol. 30, 23-28.
22. Nordberg, J., Arner, E. S. (2001) reactive oxygen species, antioxidants and the mammalian thiore-doxin system. Free Radic. Biol. Med. 31, 1287-1312. (Pubitemid 33145299)
23. Powell, C. L., Swenberg, J. A., Rusyn, I. (2005) expression of base excision dna repair genes as a biomarker of oxidative dna damage. Cancer Lett. 229, 1-11. (Pubitemid 41262535)
24. Rice-Evans, C. A., Miller, N. J., Paganda, G. (1996) structure- antioxidant activity relationships of favonoids and phenolic acids. Free Radic. Biol. Med. 20, 933-956. (Pubitemid 26157509)
25. Singh, N. P., Mccoy, M. T., Tice, R. R., Schneider, E. L. (1988) A simple technique for quantifcation of low levels of dna damage in individual cells. Exp. Cell Res. 175, 184-191.
26. Tavares, D. C., Mazzaron Barcelos, G. R., Silva, L. F., Chacon Tonin, C. C., Bastos, J. K. (2006) Propolis-induced genotoxicity and anti-genotoxicity in chinese hamster ovary cells. Toxicol. In Vitro 20, 1154-1158. (Pubitemid 44067378)
27. Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M., Telser, J. (2007) free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 39, 44-84. (Pubitemid 44566469)
28. Varanda, E. A., Monti, R., Tavares, D. C. (1999) inhibitor effect of propolis and bee venom on the mutagenicity of some direct and indirect acting mutagens. Teratog. Carcinog. Mutagen. 19, 403-413.
29. Villamor, N., Montserrat, E., Colomer, D. (2004) cytotoxic effects of b lymphocytes mediated by reactive oxygen species. Curr. Pharm. Des. 10, 841-853. (Pubitemid 38380063)
30. Vynograd, N., Vynograd, I., Sosnowski, Z. (2000) A comparative multicenter study of the effcacy of propolis, acyclovir and placebo in the treatment of genital herpes. Phytomedicine 7, 1-6. (Pubitemid 30191121)
31. Wallace, S. S. (1998) enzymatic processing of radiation-induced free radical damage in dna. Radiat. Res. 150, 560-579.
32. Waters, M. D., Brady, A. L., Stack, H. F., Brockman, H. E. (1990) Antimutagenicity profles for some model compounds. Mutat. Res. 238, 57-85.