Erratum: Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice (The Journal of Sexual Medicine (2011) 8(12) (3335–3344)(S1743609515333580)(10.1111/j.1743-6109.2011.02499.x));Extracellular Signal-Regulated Kinase (ERK) Inhibition Decreases Arginase Activity and Improves Corpora Cavernosal Relaxation in Streptozotocin (STZ)-Induced Diabetic Mice

Journal of Sexual Medicine

Volumn 8, Issue 12, 2011, Pages 3335-3344

  Nunes, Kenia P ^a   Toque, Haroldo A ^a   Caldwell, Ruth B ^a   Caldwell, R William ^a   Webb, R Clinton ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Arginase activity; Diabetes; Erectile dysfunction; ERK; Nitric oxide

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ARGINASE; ARGINASE 1; ARGINASE II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DRUG EFFECT; DRUG RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; ERECTILE DYSFUNCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES;

EID: 82955212947     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1016/S1743-6095(15)34218-1     Document Type: Erratum

References (43)

1. Moore CR, Wang R. Pathophysiology and treatment of diabetic erectile dysfunction. Asian J Androl 2006;8:675-84.
2. Hidalgo-Tamola J, Chitaley K. Review type 2 diabetes mellitus and erectile dysfunction. J Sex Med 2009;6:916-26.
3. Burnett AL, Lowenstein CJ, Bredt DS, Chang TS, Snyder SH. Nitric oxide: A physiologic mediator of penile erection. Science 1992;257:401-3.
4. Moncada S, Palmer RM, Higgs EA. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-42.
5. Burnett AL. Nitric oxide regulation of penile erection: Biology and therapeutic implications. J Androl 2002;23:S20-6.
6. Burnett AL. The role of nitric oxide in erectile dysfunction: Implications for medical therapy. J Clin Hypertens (Greenwich) 2006;8:53-62.
7. Toda N, Ayajiki K, Okamura T. Nitric oxide and penile erectile function. Pharmacol Ther 2005;106:233-66.
8. Bivalacqua TJ, Hellstrom WJ, Kadowitz PJ, Champion HC. Increased expression of arginase II in human diabetic corpus cavernosum: In diabetic-associated erectile dysfunction. Biochem Biophys Res Commun 2001;283:923-7.
9. Boucher JL, Moali C, Tenu JP. Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. Cell Mol Life Sci 1999;55:1015-28.
10. Mori M, Gotoh T. Regulation of nitric oxide production by arginine metabolic enzymes. Biochem Biophys Res Commun 2000;275:715-9.
11. Barassi A, Colpi GM, Piediferro G, Dogliotti G, D'Eril GV, Corsi MM. Oxidative stress and antioxidant status in patients with erectile dysfunction. J Sex Med 2009;6:2820-5.
12. Bivalacqua TJ, Burnett AL, Hellstrom WJ, Champion HC. Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: Influence of in vivo gene therapy of anti-arginase. Am J Physiol Heart Circ Physiol 2007;292:H1340-51.
13. Numao N, Masuda H, Sakai Y, Okada Y, Kihara K, Azuma H. Roles of attenuated neuronal nitric-oxide synthase protein expression and accelerated arginase activity in impairing neurogenic relaxation of corpus cavernosum in aged rabbits. BJU Int 2007;99:1495-9.
14. Toque HA, Tostes RC, Yao L, Xu Z, Webb RC, Caldwell RB, Caldwell RW. Arginase II deletion increases corpora cavernosa relaxation in diabetic mice. J Sex Med 2011;8:722-33.
15. Sakai Y, Masuda H, Kihara K, Kurosaki E, Yamauchi Y, Azuma H. Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit. J Urol 2004;172:369-73.
16. Burnett AL. Novel nitric oxide signaling mechanisms regulate the erectile response. Int J Impot Res 2004;16(suppl 1):S15-9.
17. Hurt KJ, Musicki B, Palese MA, Crone JK, Becker RE, Moriarity JL, Snyder SH, Burnett AL. Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection. Proc Natl Acad Sci U S A 2002;99:4061-6.
18. Bernier SG, Haldar S, Michel T. Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase. J Biol Chem 2000;275:30707-15.
19. Kyriakis JM, Avruch J. Sounding the alarm: Protein kinase cascades activated by stress and inflammation. J Biol Chem 1996;271:24313-6.
20. Sommer F, Klotz T, Steinritz D, Schmidt A, Addicks K, Engelmann U, Bloch W. MAP kinase 1/2 (Erk 1/2) and serine/threonine specific protein kinase Akt/PKB expression and activity in the human corpus cavernosum. Int J Impot Res 2002;14:217-25.
21. Tomlinson DR. Mitogen-activated protein kinases as glucose transducers for diabetic complications. Diabetologia 1999;42:1271-81.
22. Chuang CC, Yang RS, Tsai KS, Ho FM, Liu SH. Hyperglycemia enhances adipogenic induction of lipid accumulation: Involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor gamma signaling. Endocrinology 2007;148:4267-75.
23. Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 2001;44:1973-88.
24. Azadzoi KM, Saenz de Tejada I. Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle. J Urol 1992;148:1587-91.
25. Saenz de Tejada I, Goldstein I, Azadzoi K, Krane RJ, Cohen RA. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. N Engl J Med 1989;320:1025-30.
26. Romero MJ, Platt DH, Tawfik HE, Labazi M, El-Remessy AB, Bartoli M, Caldwell RB, Caldwell RW. Diabetes-induced coronary vascular dysfunction involves increased arginase activity. Circ Res 2008;102:95-102.
27. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study. J Urol 1994;151:54-61.
28. Bivalacqua TJ, Usta MF, Kendirci M, Pradhan L, Alvarez X, Champion HC, Kadowitz PJ, Hellstrom WJ. Superoxide anion production in the rat penis impairs erectile function in diabetes: Influence of in vivo extracellular superoxide dismutase gene therapy. J Sex Med 2005;2:187-97; discussion 97-8.
29. Musicki B, Burnett AL. Endothelial dysfunction in diabetic erectile dysfunction. Int J Impot Res 2007;19:129-38.
30. Masuda H, Yano M, Sakai Y, Kihara K, Yamauchi Y, Azuma H. Modulation of intrinsic cavernous tone and nitric oxide production by arginase in rabbit corpus cavernosum. J Urol 2004;171:490-4.
31. Christ GJ, Schwartz CB, Stone BA, Parker M, Janis M, Gondre M, Valcic M, Melman A. Kinetic characteristics of alpha 1-adrenergic contractions in human corpus cavernosum smooth muscle. Am J Physiol 1992;263:H15-9.
32. Nangle MR, Cotter MA, Cameron NE. The calpain inhibitor, A-705253, corrects penile nitrergic nerve dysfunction in diabetic mice. Eur J Pharmacol 2006;538:148-53.
33. Nangle MR, Cotter MA, Cameron NE. IkappaB kinase 2 inhibition corrects defective nitrergic erectile mechanisms in diabetic mouse corpus cavernosum. Urology 2006;68:214-8.
34. Chitaley K, Luttrell I. Strain differences in susceptibility to in vivo erectile dysfunction following 6 weeks of induced hyperglycemia in the mouse. J Sex Med 2008;5:1149-55.
35. Nangle MR, Cotter MA, Cameron NE. Correction of nitrergic neurovascular dysfunction in diabetic mouse corpus cavernosum by p38 mitogen-activated protein kinase inhibition. Int J Impot Res 2006;18:258-63.
36. Okon EB, Szado T, Laher I, McManus B, van Breemen C. Augmented contractile response of vascular smooth muscle in a diabetic mouse model. J Vasc Res 2003;40:520-30.
37. Cox JD, Kim NN, Traish AM, Christianson DW. Arginase-boronic acid complex highlights a physiological role in erectile function. Nat Struct Biol 1999;6:1043-7.
38. Christianson DW. Arginase: Structure, mechanism, and physiological role in male and female sexual arousal. Acc Chem Res 2005;38:191-201.
39. Musicki B, Ross AE, Champion HC, Burnett AL, Bivalacqua TJ. Posttranslational modification of constitutive nitric oxide synthase in the penis. J Androl 2009;30:352-62.
40. Singer CA, Lontay B, Unruh H, Halayko AJ, Gerthoffer WT. Src mediates cytokine-stimulated gene expression in airway myocytes through ERK MAPK. Cell Commun Signal 2011;9:14.
41. Huang Q, Guo Z, Yu Y, Ghatnekar GS, Ghatnekar AV, Bu M, Guo X, Liu S, Wang F, Feng Z, Bu S. Diazoxide inhibits aortic endothelial cell apoptosis in diabetic rats via activation of ERK. Acta Diabetol. 2011 May 3. [Epub ahead of print] doi: 10.1007/s00592-011-0288-7.
42. Cervantes D, Crosby C, Xiang Y. Arrestin orchestrates crosstalk between G protein-coupled receptors to modulate the spatiotemporal activation of ERK MAPK. Circ Res 2010;106:79-88.
43. Gratzke C, Angulo J, Chitaley K, etal. Anatomy, physiology, and pathophysiology of erectile dysfunction. J Sex Med 2010;7:445-75.