Methylation-sensitive high-resolution melting in the context of legislative requirements for validation of analytical procedures for diagnostic applications

Expert Review of Molecular Diagnostics

Volumn 12, Issue 1, 2012, Pages 39-47

  Wojdacz, Tomasz K ^a,b,c  

^a Lundbeck Foundation Centre for International Research in Radiation Oncology   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

biomarker; cancer; diagnostics; methylation; MS HRM

Indexed keywords

APC PROTEIN; BIOLOGICAL MARKER; GLUTATHIONE TRANSFERASE P1; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN P16; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TRANSCRIPTION FACTOR PITX2;

ACCURACY; DNA DENATURATION; DNA DETERMINATION; DNA METHYLATION; GENETIC PROCEDURES; LIMIT OF DETECTION; LIMIT OF QUANTITATION; METHYLATION; METHYLATION SENSITIVE HIGH RESOLUTION MELTING; POLYMERASE CHAIN REACTION; RANGE OF MOTION; REVIEW; SENSITIVITY AND SPECIFICITY;

DIAGNOSTIC TEST APPROVAL; DNA; DNA METHYLATION; HUMANS; LIMIT OF DETECTION; MOLECULAR DIAGNOSTIC TECHNIQUES; NEOPLASMS; NUCLEIC ACID DENATURATION; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 82955207575     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/erm.11.88     Document Type: Review

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