Association of heme oxygenase-1 GT-repeat polymorphism with blood pressure phenotypes and its relevance to future cardiovascular mortality risk: An observation based on arsenic-exposed individuals

Atherosclerosis

Volumn 219, Issue 2, 2011, Pages 704-708

  Wu, Meei Maan ^a,b   Chiou, Hung Yi ^a   Chen, Chi Ling ^b   Hsu, Ling I ^c   Lien, Li Ming ^d   Wang, Chih Hao ^e   Hsieh, Yi Chen ^a   Wang, Yuan Hung ^a   Hsueh, Yu Mei ^a,f   Lee, Te Chang ^g   Cheng, Wen Fang ^b   Chen, Chien Jen ^c,h  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c GENOMICS RESEARCH CENTER   (Taiwan)

^d SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^e FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^g INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^h NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Blood pressure; Cardiovascular mortality; Genetic polymorphism; Heme oxygenase 1; Population study; Risk factors

Indexed keywords

ARSENIC; HEME OXYGENASE 1; TRIACYLGLYCEROL;

ADULT; AGE DISTRIBUTION; ALLELE; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; DNA POLYMORPHISM; EFFECT SIZE; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; HYPERTENSION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PHENOTYPE; PRIORITY JOURNAL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; ARSENIC; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CHINA; CROSS-SECTIONAL STUDIES; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE FREQUENCY; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HEME OXYGENASE-1; HUMANS; HYPERTENSION; LINEAR MODELS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PHENOTYPE; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROPORTIONAL HAZARDS MODELS; REPETITIVE SEQUENCES, NUCLEIC ACID; RISK ASSESSMENT; RISK FACTORS;

EID: 82955198490     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.08.047     Document Type: Article

References (15)

1. Chen C.J., Hsueh Y.M., Lai M.S., et al. Increased prevalence of hypertension and long-term arsenic exposure. Hypertension 1995, 25(1):53-60.
2. Rahman M., Tondel M., Ahmad S.A., et al. Hypertension and arsenic exposure in Bangladesh. Hypertension 1999, 33(1):74-78.
3. Abraham N.G., Kappas A. Pharmacological clinical aspects of heme oxygenase. Pharmacol Rev 2008, 60(1):79-127.
4. Idriss N.K., Blann A.D., Lip G.Y. Hemoxygenase-1 in cardiovascular disease. J Am Coll Cardiol 2008, 52(12):971-978.
5. Taha H., Skrzypek K., Guevara I., et al. Role of heme oxygenase-1 in human endothelial cells: lesson from the promoter allelic variants. Arterioscler Thromb Vasc Biol 2010, 30(8):1634-1641.
6. Chen Y.H., Chau L.Y., Chen J.W., et al. Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients. Diabetes Care 2008, 31(8):1615-1620.
7. Kaneda H., Ohno M., Taguchi J., et al. Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors. Arterioscler Thromb Vasc Biol 2002, 22(10):1680-1685.
8. NRC Arsenic in drinking water. 2001 update 2001, NRC, Washington, DC.
9. Chen C.L., Hsu L.I., Chiou H.Y., et al. Ingested arsenic, cigarette smoking, and lung cancer risk: a follow-up study in arseniasis-endemic areas in Taiwan. JAMA 2004, 292(24):2984-2990.
10. Wu M.M., Chiou H.Y., Chen C.L., et al. GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan. Toxicol Appl Pharmacol 2010, 248(3):226-233.
11. Glynn R.J., Rosner B. Comparison of risk factors for the competing risks of coronary heart disease, stroke, and venous thromboembolism. Am J Epidemiol 2005, 162(10):975-982.
12. Gao M., Kondo F., Murakami T., et al. 1-Aminocyclopropanecarboxylic acid, an antagonist of N-methyl-d-aspartate receptors, causes hypotensive and antioxidant effects with upregulation of heme oxygenase-1 in stroke-prone spontaneously hypertensive rats. Hypertens Res 2007, 30(3):249-257.
13. Morita T., Imai T., Sugiyama T., et al. Heme oxygenase-1 in vascular smooth muscle cells counteracts cardiovascular damage induced by angiotensin II. Curr Neurovasc Res 2005, 2(2):113-120.
14. Wijpkema J.S., van Haelst P.L., Monraats P.S., et al. Restenosis after percutaneous coronary intervention is associated with the angiotensin-II type-1 receptor 1166A/C polymorphism but not with polymorphisms of angiotensin-converting enzyme, angiotensin-II receptor, angiotensinogen or heme oxygenase-1. Pharmacogenet Genomics 2006, 16(5):331-337.
15. Calabrese E.J., Baldwin L.A. Hormesis U-shaped dose responses and their centrality in toxicology. Trends Pharmacol Sci 2001, 22(6):285-291.