HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes

Journal of Neurochemistry

Volumn 119, Issue 6, 2011, Pages 1155-1161

  Kwok, Alice S ^a,b   Phadwal, Kanchan ^c   Turner, Bradley J ^a,e   Oliver, Peter L ^a   Raw, Annie ^a   Simon, Anna Katharina ^c   Talbot, Kevin ^a,d   Agashe, Vishwas R ^b,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

autophagy; molecular chaperone; neurodegeneration; peripheral nervous system; protein homeostasis

Indexed keywords

HEAT SHOCK PROTEIN 22;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE MUTATION; GENE OVEREXPRESSION; HEREDITARY DISTAL MOTOR NEUROPATHY TYPE II; HUMAN; HUMAN CELL; LYSOSOME; MOTONEURON; MOTOR DYSFUNCTION; MUTANT; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; WILD TYPE;

ANALYSIS OF VARIANCE; AUTOPHAGY; CELLS, CULTURED; CHARCOT-MARIE-TOOTH DISEASE; FLOW CYTOMETRY; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; LEUKOCYTES, MONONUCLEAR; LYSOSOMES; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NEUROBLASTOMA; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; SUPEROXIDE DISMUTASE; TRANSFECTION;

EID: 82955187310     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07521.x     Document Type: Article

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