메뉴 건너뛰기




Volumn 4, Issue 5, 2011, Pages 514-521

CYP2C19 genetic testing should not be done in all patients treated with clopidogrel who are undergoing percutaneous coronary intervention

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; CYTOCHROME P450 2C19; PRASUGREL; ANTITHROMBOCYTIC AGENT; CYP2C19 PROTEIN, HUMAN; DRUG DERIVATIVE; PHARMACOLOGICAL BIOMARKER; TICLOPIDINE; UNSPECIFIC MONOOXYGENASE;

EID: 82955173054     PISSN: 19417640     EISSN: 19417632     Source Type: Journal    
DOI: 10.1161/CIRCINTERVENTIONS.111.962142     Document Type: Article
Times cited : (20)

References (34)
  • 3
    • 70350332201 scopus 로고    scopus 로고
    • A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel
    • Hagihara K, Kazui M, Kurihara A, Yoshiike M, Honda K, Okazaki O, Farid NA, Ikeda T. A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel. Drug Metab Dispos. 2009; 37:2145-2152.
    • (2009) Drug Metab Dispos. , vol.37 , pp. 2145-2152
    • Hagihara, K.1    Kazui, M.2    Kurihara, A.3    Yoshiike, M.4    Honda, K.5    Okazaki, O.6    Farid, N.A.7    Ikeda, T.8
  • 4
    • 73149119363 scopus 로고    scopus 로고
    • Identification of the human cytochrome p450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
    • Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A. Identification of the human cytochrome p450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos. 2010;38:92-99.
    • (2010) Drug Metab Dispos. , vol.38 , pp. 92-99
    • Kazui, M.1    Nishiya, Y.2    Ishizuka, T.3    Hagihara, K.4    Farid, N.A.5    Okazaki, O.6    Ikeda, T.7    Kurihara, A.8
  • 5
    • 78049492640 scopus 로고    scopus 로고
    • Carriage of cytochrome 2c19 polymorphism is associated with risk of high post-treatment platelet reactivity on high maintenance- dose clopidogrel of 150 mg/day: Results of the ACCEL-DOUBLE (Accelerated Platelet Inhibition by a Double Dose of Clopidogrel According to Gene Polymorphism) study
    • Jeong YH, Kim IS, Park Y, Kang MK, Koh JS, Hwang SJ, Kwak CH, Hwang JY. Carriage of cytochrome 2c19 polymorphism is associated with risk of high post-treatment platelet reactivity on high maintenance- dose clopidogrel of 150 mg/day: results of the ACCEL-DOUBLE (Accelerated Platelet Inhibition by a Double Dose of Clopidogrel According to Gene Polymorphism) study. J Am Coll Cardiol Cardiovasc Interv. 2010;3:731-741.
    • (2010) J Am Coll Cardiol Cardiovasc Interv. , vol.3 , pp. 731-741
    • Jeong, Y.H.1    Kim, I.S.2    Park, Y.3    Kang, M.K.4    Koh, J.S.5    Hwang, S.J.6    Kwak, C.H.7    Hwang, J.Y.8
  • 15
    • 77958100874 scopus 로고    scopus 로고
    • Effect of CYP2c19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
    • Wallentin L, James S, Storey RF, Armstrong M, Barratt BJ, Horrow J, Husted S, Katus H, Steg PG, Shah SH, Becker RC. Effect of CYP2c19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet. 2010;376:1320-1328.
    • (2010) Lancet , vol.376 , pp. 1320-1328
    • Wallentin, L.1    James, S.2    Storey, R.F.3    Armstrong, M.4    Barratt, B.J.5    Horrow, J.6    Husted, S.7    Katus, H.8    Steg, P.G.9    Shah, S.H.10    Becker, R.C.11
  • 17
    • 0037078968 scopus 로고    scopus 로고
    • C-reactive protein to screen or not to screen?
    • Mosca L. C-reactive protein: to screen or not to screen? N Engl J Med. 2002;347:1615-1617.
    • (2002) N Engl J Med. , vol.347 , pp. 1615-1617
    • Mosca, L.1
  • 18
    • 43049179414 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents
    • DOI 10.1016/j.jacc.2007.12.056, PII S0735109708008656
    • Trenk D, Hochholzer W, Fromm MF, Chialda LE, Pahl A, Valina CM, Stratz C, Schmiebusch P, Bestehorn HP, Buttner HJ, Neumann FJ. Cytochrome P450 2c19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents. J Am Coll Cardiol. 2008;51:1925-1934. (Pubitemid 351636443)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.20 , pp. 1925-1934
    • Trenk, D.1    Hochholzer, W.2    Fromm, M.F.3    Chialda, L.-E.4    Pahl, A.5    Valina, C.M.6    Stratz, C.7    Schmiebusch, P.8    Bestehorn, H.-P.9    Buttner, H.J.10    Neumann, F.-J.11
  • 20
    • 77953886152 scopus 로고    scopus 로고
    • Carriage of the CYP2c19*2 allele increases one-year risk of myocardial infarction among recipients of drug-eluting stents treated with clopidogrel
    • Anderson JL, Mower CP, Horne BD, Muhlestein JB, Park JJ, Bair TL, Carlquist JF. Carriage of the CYP2c19*2 allele increases one-year risk of myocardial infarction among recipients of drug-eluting stents treated with clopidogrel. J Am Coll Cardiol. 2009;53:A1-A99.
    • (2009) J Am Coll Cardiol. , vol.53
    • Anderson, J.L.1    Mower, C.P.2    Horne, B.D.3    Muhlestein, J.B.4    Park, J.J.5    Bair, T.L.6    Carlquist, J.F.7
  • 21
    • 78650509811 scopus 로고    scopus 로고
    • The cytochrome CYP2c19*2 and *3 alleles attenuate response to clopidogrel similarly in east asian patients undergoing elective percutaneous coronary intervention
    • Hwang SJ, Jeong YH, Kim IS, Koh JS, Kang MK, Park Y, Kwak CH, Hwang JY. The cytochrome CYP2c19*2 and *3 alleles attenuate response to clopidogrel similarly in East Asian patients undergoing elective percutaneous coronary intervention. Thromb Res. 2011;127:23-28.
    • (2011) Thromb Res. , vol.127 , pp. 23-28
    • Hwang, S.J.1    Jeong, Y.H.2    Kim, I.S.3    Koh, J.S.4    Kang, M.K.5    Park, Y.6    Kwak, C.H.7    Hwang, J.Y.8
  • 22
    • 34248347478 scopus 로고    scopus 로고
    • The pharmacogenetics of CYP2C9 and CYP2C19: Ethnic variation and clinical significance
    • Rosemary J, Adithan C. The pharmacogenetics of CYP2C9 and CYP2c19: ethnic variation and clinical significance. Curr Clin Pharmacol. 2007;2:93-109. (Pubitemid 46729082)
    • (2007) Current Clinical Pharmacology , vol.2 , Issue.1 , pp. 93-109
    • Rosemary, J.1    Adithan, C.2
  • 23
    • 77955638355 scopus 로고    scopus 로고
    • ACCF/AHA clopidogrel clinical alert: Approaches to the FDA"boxed warning": A report of the american college of cardiology foundation task force on clinical expert consensus documents and the american heart association, endorsed by the society for cardiovascular angiography and interventions and the society of thoracic surgeons
    • Holmes DR Jr, Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed 520 Circ Cardiovasc Interv October 2011 Downloaded from circinterventions.ahajournals.org by Gerrit Jan KRAMER on December 7, 2011 warning": a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association, endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2010;56:321-341.
    • (2010) J Am Coll Cardiol. , vol.56 , pp. 321-341
    • Holmes Jr., D.R.1    Dehmer, G.J.2    Kaul, S.3    Leifer, D.4    O'Gara, P.T.5    Stein, C.M.6
  • 24
    • 77956353400 scopus 로고    scopus 로고
    • Protective effect of the CYP2c19*17 polymorphism with increased activation of clopidogrel on cardiovascular events
    • Tiroch KA, Sibbing D, Koch W, Roosen-Runge T, Mehilli J, Schomig A, Kastrati A. Protective effect of the CYP2c19*17 polymorphism with increased activation of clopidogrel on cardiovascular events. Am Heart J. 2010;160:506-512.
    • (2010) Am Heart J. , vol.160 , pp. 506-512
    • Tiroch, K.A.1    Sibbing, D.2    Koch, W.3    Roosen-Runge, T.4    Mehilli, J.5    Schomig, A.6    Kastrati, A.7
  • 25
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2c19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • Sibbing D, Koch W, Gebhard D, Schuster T, Braun S, Stegherr J, Morath T, Schomig A, von Beckerath N, Kastrati A. Cytochrome 2c19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation. 2010;121:512-518.
    • (2010) Circulation , vol.121 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3    Schuster, T.4    Braun, S.5    Stegherr, J.6    Morath, T.7    Schomig, A.8    Von Beckerath, N.9    Kastrati, A.10
  • 27
    • 33646732608 scopus 로고    scopus 로고
    • Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
    • Jernberg T, Payne CD, Winters KJ, Darstein C, Brandt JT, Jakubowski JA, Naganuma H, Siegbahn A, Wallentin L. Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease. Eur Heart J. 2006;27:1166-1173.
    • (2006) Eur Heart J. , vol.27 , pp. 1166-1173
    • Jernberg, T.1    Payne, C.D.2    Winters, K.J.3    Darstein, C.4    Brandt, J.T.5    Jakubowski, J.A.6    Naganuma, H.7    Siegbahn, A.8    Wallentin, L.9
  • 31
    • 78650387026 scopus 로고    scopus 로고
    • Randomized comparison of platelet function monitoring to adjust antiplatelet therapy versus standard of care: Rationale and design of the assessment with a double randomization of (1) a fixed dose versus a monitoring-guided dose of aspirin and clopidogrel after des implantation, and (2) treatment interruption versus continuation, 1 year after stenting (ARCTIC) study
    • Collet JP, Cayla G, Cuisset T, Elhadad S, Range G, Vicaut E, Montalescot G. Randomized comparison of platelet function monitoring to adjust antiplatelet therapy versus standard of care: rationale and design of the assessment with a double randomization of (1) a fixed dose versus a monitoring-guided dose of aspirin and clopidogrel after des implantation, and (2) treatment interruption versus continuation, 1 year after stenting (ARCTIC) study. Am Heart J. 2011;161:5e15-12e15.
    • (2011) Am Heart J. , vol.161
    • Collet, J.P.1    Cayla, G.2    Cuisset, T.3    Elhadad, S.4    Range, G.5    Vicaut, E.6    Montalescot, G.7
  • 34
    • 79955492923 scopus 로고    scopus 로고
    • Pharmacogenomics: The genetics of variable drug responses
    • Roden DM, Wilke RA, Kroemer HK, Stein CM. Pharmacogenomics: the genetics of variable drug responses. Circulation. 2011;123:1661-1670.
    • (2011) Circulation , vol.123 , pp. 1661-1670
    • Roden, D.M.1    Wilke, R.A.2    Kroemer, H.K.3    Stein, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.