Defluorination-silylation of alkyl trifluoroacetates to 2,2-difluoro-2-(trimethylsilyl)acetates by copper-deposited magnesium and trimethylsilyl chloride

Tetrahedron

Volumn 68, Issue 2, 2012, Pages 580-583

  Utsumi, Shinya ^a   Katagiri, Toshimasa ^a   Uneyama, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Copper deposited magnesium; Difluoromethylene building block; Electron transfer; Reduction by magnesium metal; Reductive defluorination silylation reaction from trifluoroaceates

Indexed keywords

ACETIC ACID DERIVATIVE; CHLOROTRIMETHYLSILANE; COPPER; CYCLOHEXYL 2,2 DIFLUORO 2 (TRIMETHYLSILYL)ACETATE; CYCLOHEXYL SILYL KETAL; ETHYL 2,2 DIFLUORO 2 (TRIMETHYLSILYL)ACETATE; I PROPYL 2,2 DIFLUORO 2 (TRIMETHYLSILYL)ACETATE; ISOPROPYL SILYL KETAL; MAGNESIUM; N HEXYL 2,2 DIFLUORO 2 (TRIMETHYLSILYL)ACETATE; UNCLASSIFIED DRUG;

ARTICLE; DEFLUORINATION; PRIORITY JOURNAL; QUANTUM YIELD; REDUCTION; SILYLATION;

EID: 82955167820     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.10.109     Document Type: Article

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