The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice

Biomaterials

Volumn 33, Issue 1, 2012, Pages 317-324

  Suzuki, Hidehiko ^a   Kondoh, Masuo ^a   Kakutani, Hideki ^a   Yamane, Seiji ^a   Uchida, Hiroshi ^b   Hamakubo, Takao ^c   Yagi, Kiyohito ^a  

^a OSAKA UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Claudin; Clostridium perfringens enterotoxin; Mucosal vaccine; Targeting

Indexed keywords

ANTI-TUMOR ACTIVITIES; C-TERMINAL FRAGMENTS; CLAUDIN; CLOSTRIDIUM PERFRINGENS; ENTEROTOXIN; EPITHELIAL CELLS; FUSION PROTEINS; MUCOSAL VACCINE; OVALBUMINS; TARGETING;

AMINO ACIDS; ANTIGENS; CLOSTRIDIUM; HISTOLOGY; IMMUNIZATION; MAMMALS; TISSUE;

VACCINES;

ALANINE; CLAUDIN 4; ENTEROTOXIN; HYBRID PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; OVALBUMIN; VACCINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; FEMALE; IMMUNIZATION; MOUSE; MUCOSA; MUTANT; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; THYMOMA;

ALANINE; ANIMALS; BACTERIAL VACCINES; CLAUDINS; CLOSTRIDIUM INFECTIONS; CLOSTRIDIUM PERFRINGENS; ENTEROTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MICE; MICE, INBRED BALB C; MUCOUS MEMBRANE; OVALBUMIN;

CLOSTRIDIUM PERFRINGENS; MUS;

EID: 82855172091     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.048     Document Type: Article

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