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Volumn 45, Issue 4, 2011, Pages 241-247

Alternative Medical Treatment for Radioiodine-Refractory Thyroid Cancers

Author keywords

Radioiodine refractory; Redifferentiation; Thyroid cancer; Tyrosine kinase inhibitor

Indexed keywords

AXITINIB; BEXAROTENE; DEPSIPEPTIDE; DOXORUBICIN; ENTINOSTAT; GEFITINIB; GLITAZONE DERIVATIVE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; ISOTRETINOIN; MOTESANIB; PAZOPANIB; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEASOME INHIBITOR; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; RADIOACTIVE IODINE; RETINOIC ACID; ROSIGLITAZONE; SORAFENIB; SUNITINIB; TRICHOSTATIN A; TROGLITAZONE; VALPROIC ACID; VORINOSTAT;

EID: 82855161024     PISSN: 18693474     EISSN: 18693482     Source Type: Journal    
DOI: 10.1007/s13139-011-0107-7     Document Type: Review
Times cited : (13)

References (60)
  • 1
    • 77956627478 scopus 로고    scopus 로고
    • Cancer statistics in Korea: incidence, mortality and survival in 2006-2007
    • Jung KW, Park S, Kong HJ, Won YJ, Boo YK, Shin HR, et al. Cancer statistics in Korea: incidence, mortality and survival in 2006-2007. J Korean Med Sci. 2010; 25: 1113-21.
    • (2010) J Korean Med Sci. , vol.25 , pp. 1113-1121
    • Jung, K.W.1    Park, S.2    Kong, H.J.3    Won, Y.J.4    Boo, Y.K.5    Shin, H.R.6
  • 2
    • 79958814789 scopus 로고    scopus 로고
    • Cancer statistics in Korea: Incidence, mortality, survival, and prevalence in 2008
    • Jung KW, Park S, Kong HJ, Won YJ, Lee JY, Park EC, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2008. Cancer Res Treat. 2011; 43: 1-11.
    • (2011) Cancer Res Treat. , vol.43 , pp. 1-11
    • Jung, K.W.1    Park, S.2    Kong, H.J.3    Won, Y.J.4    Lee, J.Y.5    Park, E.C.6
  • 4
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 2011; 61: 212-36.
    • (2011) CA Cancer J Clin. , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 5
    • 0036732003 scopus 로고    scopus 로고
    • Sodium iodide symporter: its role in nuclear medicine
    • Chung JK. Sodium iodide symporter: its role in nuclear medicine. J Nucl Med. 2002; 43: 1188-200.
    • (2002) J Nucl Med. , vol.43 , pp. 1188-1200
    • Chung, J.K.1
  • 6
    • 0037187359 scopus 로고    scopus 로고
    • The promoter of the human sodium/iodide-symporter gene responds to retinoic acid
    • Schmutzler C, Schmitt TL, Glaser F, Loos U, Kohrle J. The promoter of the human sodium/iodide-symporter gene responds to retinoic acid. Mol Cell Endocrinol. 2002; 189: 145-55.
    • (2002) Mol Cell Endocrinol , vol.189 , pp. 145-155
    • Schmutzler, C.1    Schmitt, T.L.2    Glaser, F.3    Loos, U.4    Kohrle, J.5
  • 7
    • 33749430081 scopus 로고    scopus 로고
    • Effect of all-trans retinoic acid on sodium/iodide symporter expression, radioiodine uptake and gene expression profiles in a human anaplastic thyroid carcinoma cell line
    • Jeong H, Kim YR, Kim KN, Choe JG, Chung JK, Kim MK. Effect of all-trans retinoic acid on sodium/iodide symporter expression, radioiodine uptake and gene expression profiles in a human anaplastic thyroid carcinoma cell line. Nucl Med Biol. 2006; 33: 875-82.
    • (2006) Nucl Med Biol. , vol.33 , pp. 875-882
    • Jeong, H.1    Kim, Y.R.2    Kim, K.N.3    Choe, J.G.4    Chung, J.K.5    Kim, M.K.6
  • 9
    • 0029957636 scopus 로고    scopus 로고
    • Redifferentiation therapy of differentiated thyroid carcinoma with retinoic acid: basics and first clinical results
    • Simon D, Kohrle J, Schmutzler C, Mainz K, Reiners C, Roher HD. Redifferentiation therapy of differentiated thyroid carcinoma with retinoic acid: basics and first clinical results. Exp Clin Endocrinol Diabetes. 1996; 104 Suppl 4: 13-5.
    • (1996) Exp Clin Endocrinol Diabetes. , vol.104 , Issue.SUPPL. 4 , pp. 13-15
    • Simon, D.1    Kohrle, J.2    Schmutzler, C.3    Mainz, K.4    Reiners, C.5    Roher, H.D.6
  • 10
  • 11
    • 0031950351 scopus 로고    scopus 로고
    • Redifferentiation therapy with retinoids: therapeutic option for advanced follicular and papillary thyroid carcinoma
    • Simon D, Koehrle J, Reiners C, Boerner AR, Schmutzler C, Mainz K, et al. Redifferentiation therapy with retinoids: therapeutic option for advanced follicular and papillary thyroid carcinoma. World J Surg. 1998; 22: 569-74.
    • (1998) World J Surg. , vol.22 , pp. 569-574
    • Simon, D.1    Koehrle, J.2    Reiners, C.3    Boerner, A.R.4    Schmutzler, C.5    Mainz, K.6
  • 12
    • 0036597118 scopus 로고    scopus 로고
    • Clinical impact of retinoids in redifferentiation therapy of advanced thyroid cancer: final results of a pilot study
    • Simon D, Korber C, Krausch M, Segering J, Groth P, Gorges R, et al. Clinical impact of retinoids in redifferentiation therapy of advanced thyroid cancer: final results of a pilot study. Eur J Nucl Med Mol Imaging. 2002; 29: 775-82.
    • (2002) Eur J Nucl Med Mol Imaging. , vol.29 , pp. 775-782
    • Simon, D.1    Korber, C.2    Krausch, M.3    Segering, J.4    Groth, P.5    Gorges, R.6
  • 13
    • 8744254517 scopus 로고    scopus 로고
    • A phase II study using retinoids as redifferentiation agents to increase iodine uptake in metastatic thyroid cancer
    • Short SC, Suovuori A, Cook G, Vivian G, Harmer C. A phase II study using retinoids as redifferentiation agents to increase iodine uptake in metastatic thyroid cancer. Clin Oncol (R Coll Radiol). 2004; 16: 569-74.
    • (2004) Clin Oncol (R Coll Radiol). , vol.16 , pp. 569-574
    • Short, S.C.1    Suovuori, A.2    Cook, G.3    Vivian, G.4    Harmer, C.5
  • 14
    • 33846459070 scopus 로고    scopus 로고
    • Defective efficacy of retinoic acid treatment in patients with metastatic thyroid carcinoma
    • Courbon F, Zerdoud S, Bastie D, Archambaud F, Hoff M, Eche N, et al. Defective efficacy of retinoic acid treatment in patients with metastatic thyroid carcinoma. Thyroid. 2006; 16: 1025-31.
    • (2006) Thyroid , vol.16 , pp. 1025-1031
    • Courbon, F.1    Zerdoud, S.2    Bastie, D.3    Archambaud, F.4    Hoff, M.5    Eche, N.6
  • 15
    • 77952543012 scopus 로고    scopus 로고
    • 13-cis-retinoic acid re-differentiation therapy and recombinant human thyrotropin-aided radioiodine treatment of non-Functional metastatic thyroid cancer: a single-center, 53-patient phase 2 study
    • Handkiewicz-Junak D, Roskosz J, Hasse-Lazar K, Szpak-Ulczok S, Puch Z, Kukulska A, et al. 13-cis-retinoic acid re-differentiation therapy and recombinant human thyrotropin-aided radioiodine treatment of non-Functional metastatic thyroid cancer: a single-center, 53-patient phase 2 study. Thyroid Res. 2009; 2: 8.
    • (2009) Thyroid Res , vol.2 , pp. 8
    • Handkiewicz-Junak, D.1    Roskosz, J.2    Hasse-Lazar, K.3    Szpak-Ulczok, S.4    Puch, Z.5    Kukulska, A.6
  • 16
    • 62549109145 scopus 로고    scopus 로고
    • Redifferentiation therapy with 13-cis retinoic acids in radioiodine-resistant thyroid cancer
    • Kim WG, Kim EY, Kim TY, Ryu JS, Hong SJ, Kim WB, et al. Redifferentiation therapy with 13-cis retinoic acids in radioiodine-resistant thyroid cancer. Endocr J. 2009; 56: 105-12.
    • (2009) Endocr J , vol.56 , pp. 105-112
    • Kim, W.G.1    Kim, E.Y.2    Kim, T.Y.3    Ryu, J.S.4    Hong, S.J.5    Kim, W.B.6
  • 17
    • 34247620449 scopus 로고    scopus 로고
    • A clinical study of all-trans-retinoid-induced differentiation therapy of advanced thyroid cancer
    • Zhang Y, Jia S, Liu Y, Li B, Wang Z, Lu H, et al. A clinical study of all-trans-retinoid-induced differentiation therapy of advanced thyroid cancer. Nucl Med Commun. 2007; 28: 251-5.
    • (2007) Nucl Med Commun. , vol.28 , pp. 251-255
    • Zhang, Y.1    Jia, S.2    Liu, Y.3    Li, B.4    Wang, Z.5    Lu, H.6
  • 18
    • 67651245149 scopus 로고    scopus 로고
    • Effectiveness of retinoic acid treatment for redifferentiation of thyroid cancer in relation to recovery of radioiodine uptake
    • Fernandez CA, Puig-Domingo M, Lomena F, Estorch M, Camacho Marti V, Bittini AL, et al. Effectiveness of retinoic acid treatment for redifferentiation of thyroid cancer in relation to recovery of radioiodine uptake. J Endocrinol Invest. 2009; 32: 228-33.
    • (2009) J Endocrinol Invest. , vol.32 , pp. 228-233
    • Fernandez, C.A.1    Puig-Domingo, M.2    Lomena, F.3    Estorch, M.4    Camacho Marti, V.5    Bittini, A.L.6
  • 19
    • 80455174021 scopus 로고    scopus 로고
    • Combined therapy with (131)I and retinoic acid in Korean patients with radioiodine-refractory papillary thyroid cancer
    • Oh SW, Moon SH, Park DJ, Cho BY, Jung KC, Lee DS, et al. Combined therapy with (131)I and retinoic acid in Korean patients with radioiodine-refractory papillary thyroid cancer. Eur J Nucl Med Mol Imaging. 2011.
    • (2011) Eur J Nucl Med Mol Imaging
    • Oh, S.W.1    Moon, S.H.2    Park, D.J.3    Cho, B.Y.4    Jung, K.C.5    Lee, D.S.6
  • 21
    • 0034913856 scopus 로고    scopus 로고
    • Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/I(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells
    • Kitazono M, Robey R, Zhan Z, Sarlis NJ, Skarulis MC, Aikou T, et al. Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/I(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells. J Clin Endocrinol Metab. 2001; 86: 3430-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3430-3435
    • Kitazono, M.1    Robey, R.2    Zhan, Z.3    Sarlis, N.J.4    Skarulis, M.C.5    Aikou, T.6
  • 22
    • 2542458413 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin
    • Furuya F, Shimura H, Suzuki H, Taki K, Ohta K, Haraguchi K, et al. Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin. Endocrinology. 2004; 145: 2865-75.
    • (2004) Endocrinology , vol.145 , pp. 2865-2875
    • Furuya, F.1    Shimura, H.2    Suzuki, H.3    Taki, K.4    Ohta, K.5    Haraguchi, K.6
  • 23
    • 0036910932 scopus 로고    scopus 로고
    • Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor
    • discussion 90
    • Zarnegar R, Brunaud L, Kanauchi H, Wong M, Fung M, Ginzinger D, et al. Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor. Surgery. 2002; 132: 984-90. discussion 90.
    • (2002) Surgery , vol.132 , pp. 984-990
    • Zarnegar, R.1    Brunaud, L.2    Kanauchi, H.3    Wong, M.4    Fung, M.5    Ginzinger, D.6
  • 24
    • 1442352159 scopus 로고    scopus 로고
    • Valproic acid induces the expression of the Na+/I- symporter and iodine uptake in poorly differentiated thyroid cancer cells
    • Fortunati N, Catalano MG, Arena K, Brignardello E, Piovesan A, Boccuzzi G. Valproic acid induces the expression of the Na+/I- symporter and iodine uptake in poorly differentiated thyroid cancer cells. J Clin Endocrinol Metab. 2004; 89: 1006-9.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1006-1009
    • Fortunati, N.1    Catalano, M.G.2    Arena, K.3    Brignardello, E.4    Piovesan, A.5    Boccuzzi, G.6
  • 25
    • 23844465613 scopus 로고    scopus 로고
    • Effects of histone acetylation on sodium iodide symporter promoter and expression of thyroid-specific transcription factors
    • Puppin C, D'Aurizio F, D'Elia AV, Cesaratto L, Tell G, Russo D, et al. Effects of histone acetylation on sodium iodide symporter promoter and expression of thyroid-specific transcription factors. Endocrinology. 2005; 146: 3967-74.
    • (2005) Endocrinology , vol.146 , pp. 3967-3974
    • Puppin, C.1    D'Aurizio, F.2    D'Elia, A.V.3    Cesaratto, L.4    Tell, G.5    Russo, D.6
  • 26
  • 27
    • 29144445219 scopus 로고    scopus 로고
    • Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells
    • discussion 84-5
    • Shen WT, Wong TS, Chung WY, Wong MG, Kebebew E, Duh QY, et al. Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells. Surgery. 2005; 138: 979-84. discussion 84-5.
    • (2005) Surgery , vol.138 , pp. 979-984
    • Shen, W.T.1    Wong, T.S.2    Chung, W.Y.3    Wong, M.G.4    Kebebew, E.5    Duh, Q.Y.6
  • 28
    • 33749331568 scopus 로고    scopus 로고
    • Antitumor activity of suberoylanilide hydroxamic acid against thyroid cancer cell lines in vitro and in vivo
    • Luong QT, O'Kelly J, Braunstein GD, Hershman JM, Koeffler HP. Antitumor activity of suberoylanilide hydroxamic acid against thyroid cancer cell lines in vitro and in vivo. Clin Cancer Res. 2006; 12: 5570-7.
    • (2006) Clin Cancer Res. , vol.12 , pp. 5570-5577
    • Luong, Q.T.1    O'Kelly, J.2    Braunstein, G.D.3    Hershman, J.M.4    Koeffler, H.P.5
  • 30
    • 21244464349 scopus 로고    scopus 로고
    • Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer
    • Kelly WK, O'Connor OA, Krug LM, Chiao JH, Heaney M, Curley T, et al. Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer. J Clin Oncol. 2005; 23: 3923-31.
    • (2005) J Clin Oncol , vol.23 , pp. 3923-3931
    • Kelly, W.K.1    O'Connor, O.A.2    Krug, L.M.3    Chiao, J.H.4    Heaney, M.5    Curley, T.6
  • 31
    • 58149387609 scopus 로고    scopus 로고
    • Lack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with metastatic radioiodine-refractory thyroid carcinoma
    • Woyach JA, Kloos RT, Ringel MD, Arbogast D, Collamore M, Zwiebel JA, et al. Lack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with metastatic radioiodine-refractory thyroid carcinoma. J Clin Endocrinol Metab. 2009; 94: 164-70.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 164-170
    • Woyach, J.A.1    Kloos, R.T.2    Ringel, M.D.3    Arbogast, D.4    Collamore, M.5    Zwiebel, J.A.6
  • 32
    • 0036776260 scopus 로고    scopus 로고
    • A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy
    • Imanishi R, Ohtsuru A, Iwamatsu M, Iioka T, Namba H, Seto S, et al. A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy. J Clin Endocrinol Metab. 2002; 87: 4821-4.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4821-4824
    • Imanishi, R.1    Ohtsuru, A.2    Iwamatsu, M.3    Iioka, T.4    Namba, H.5    Seto, S.6
  • 33
    • 33751505528 scopus 로고    scopus 로고
    • Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells
    • Catalano MG, Fortunati N, Pugliese M, Poli R, Bosco O, Mastrocola R, et al. Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells. J Endocrinol. 2006; 191: 465-72.
    • (2006) J Endocrinol , vol.191 , pp. 465-472
    • Catalano, M.G.1    Fortunati, N.2    Pugliese, M.3    Poli, R.4    Bosco, O.5    Mastrocola, R.6
  • 34
    • 73849114072 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation
    • Borbone E, Berlingieri MT, De Bellis F, Nebbioso A, Chiappetta G, Mai A, et al. Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation. Oncogene. 2010; 29: 105-16.
    • (2010) Oncogene , vol.29 , pp. 105-116
    • Borbone, E.1    Berlingieri, M.T.2    de Bellis, F.3    Nebbioso, A.4    Chiappetta, G.5    Mai, A.6
  • 35
    • 76149087747 scopus 로고    scopus 로고
    • Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways
    • Hou P, Bojdani E, Xing M. Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways. J Clin Endocrinol Metab. 2010; 95: 820-8.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 820-828
    • Hou, P.1    Bojdani, E.2    Xing, M.3
  • 36
    • 66849128440 scopus 로고    scopus 로고
    • Successful treatment of anaplastic thyroid carcinoma with a combination of oral valproic acid, chemotherapy, radiation and surgery
    • Noguchi H, Yamashita H, Murakami T, Hirai K, Noguchi Y, Maruta J, et al. Successful treatment of anaplastic thyroid carcinoma with a combination of oral valproic acid, chemotherapy, radiation and surgery. Endocr J. 2009; 56: 245-9.
    • (2009) Endocr J , vol.56 , pp. 245-249
    • Noguchi, H.1    Yamashita, H.2    Murakami, T.3    Hirai, K.4    Noguchi, Y.5    Maruta, J.6
  • 37
    • 26944453579 scopus 로고    scopus 로고
    • Evaluation of peroxisome proliferator-activated receptor-gamma expression in benign and malignant thyroid pathologies
    • Karger S, Berger K, Eszlinger M, Tannapfel A, Dralle H, Paschke R, et al. Evaluation of peroxisome proliferator-activated receptor-gamma expression in benign and malignant thyroid pathologies. Thyroid. 2005; 15: 997-1003.
    • (2005) Thyroid , vol.15 , pp. 997-1003
    • Karger, S.1    Berger, K.2    Eszlinger, M.3    Tannapfel, A.4    Dralle, H.5    Paschke, R.6
  • 38
    • 0036949695 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activation induces cell cycle arrest via the p53-independent pathway in human anaplastic thyroid cancer cells
    • Chung SH, Onoda N, Ishikawa T, Ogisawa K, Takenaka C, Yano Y, et al. Peroxisome proliferator-activated receptor gamma activation induces cell cycle arrest via the p53-independent pathway in human anaplastic thyroid cancer cells. Jpn J Cancer Res. 2002; 93: 1358-65.
    • (2002) Jpn J Cancer Res. , vol.93 , pp. 1358-1365
    • Chung, S.H.1    Onoda, N.2    Ishikawa, T.3    Ogisawa, K.4    Takenaka, C.5    Yano, Y.6
  • 39
    • 18644367272 scopus 로고    scopus 로고
    • Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth
    • Martelli ML, Iuliano R, Le Pera I, Sama I, Monaco C, Cammarota S, et al. Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth. J Clin Endocrinol Metab. 2002; 87: 4728-35.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4728-4735
    • Martelli, M.L.1    Iuliano, R.2    Le Pera, I.3    Sama, I.4    Monaco, C.5    Cammarota, S.6
  • 40
    • 20144367845 scopus 로고    scopus 로고
    • Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines
    • Park JW, Zarnegar R, Kanauchi H, Wong MG, Hyun WC, Ginzinger DG, et al. Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines. Thyroid. 2005; 15: 222-31.
    • (2005) Thyroid , vol.15 , pp. 222-231
    • Park, J.W.1    Zarnegar, R.2    Kanauchi, H.3    Wong, M.G.4    Hyun, W.C.5    Ginzinger, D.G.6
  • 41
    • 33747610958 scopus 로고    scopus 로고
    • Peroxisomal proliferator-activated receptor-gamma agonists induce partial reversion of epithelial-mesenchymal transition in anaplastic thyroid cancer cells
    • Aiello A, Pandini G, Frasca F, Conte E, Murabito A, Sacco A, et al. Peroxisomal proliferator-activated receptor-gamma agonists induce partial reversion of epithelial-mesenchymal transition in anaplastic thyroid cancer cells. Endocrinology. 2006; 147: 4463-75.
    • (2006) Endocrinology , vol.147 , pp. 4463-4475
    • Aiello, A.1    Pandini, G.2    Frasca, F.3    Conte, E.4    Murabito, A.5    Sacco, A.6
  • 42
    • 3843054802 scopus 로고    scopus 로고
    • Antitumor effects of peroxisome proliferator activate receptor gamma ligands on anaplastic thyroid carcinoma
    • Hayashi N, Nakamori S, Hiraoka N, Tsujie M, Xundi X, Takano T, et al. Antitumor effects of peroxisome proliferator activate receptor gamma ligands on anaplastic thyroid carcinoma. Int J Oncol. 2004; 24: 89-95.
    • (2004) Int J Oncol , vol.24 , pp. 89-95
    • Hayashi, N.1    Nakamori, S.2    Hiraoka, N.3    Tsujie, M.4    Xundi, X.5    Takano, T.6
  • 43
    • 21244506742 scopus 로고    scopus 로고
    • Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture
    • Frohlich E, Machicao F, Wahl R. Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture. Endocr Relat Cancer. 2005; 12: 291-303.
    • (2005) Endocr Relat Cancer. , vol.12 , pp. 291-303
    • Frohlich, E.1    Machicao, F.2    Wahl, R.3
  • 44
    • 10144233475 scopus 로고    scopus 로고
    • Effect of peroxisome proliferator-activated receptor gamma agonist, rosiglitazone, on dedifferentiated thyroid cancers
    • Philips JC, Petite C, Willi JP, Buchegger F, Meier CA. Effect of peroxisome proliferator-activated receptor gamma agonist, rosiglitazone, on dedifferentiated thyroid cancers. Nucl Med Commun. 2004; 25: 1183-6.
    • (2004) Nucl Med Commun. , vol.25 , pp. 1183-1186
    • Philips, J.C.1    Petite, C.2    Willi, J.P.3    Buchegger, F.4    Meier, C.A.5
  • 45
    • 33845561938 scopus 로고    scopus 로고
    • A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer
    • discussion 6-7
    • Kebebew E, Peng M, Reiff E, Treseler P, Woeber KA, Clark OH, et al. A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer. Surgery. 2006; 140: 960-6. discussion 6-7.
    • (2006) Surgery , vol.140 , pp. 960-966
    • Kebebew, E.1    Peng, M.2    Reiff, E.3    Treseler, P.4    Woeber, K.A.5    Clark, O.H.6
  • 46
    • 70349160428 scopus 로고    scopus 로고
    • Results of rosiglitazone therapy in patients with thyroglobulin-positive and radioiodine-negative advanced differentiated thyroid cancer
    • Kebebew E, Lindsay S, Clark OH, Woeber KA, Hawkins R, Greenspan FS. Results of rosiglitazone therapy in patients with thyroglobulin-positive and radioiodine-negative advanced differentiated thyroid cancer. Thyroid. 2009; 19: 953-6.
    • (2009) Thyroid , vol.19 , pp. 953-956
    • Kebebew, E.1    Lindsay, S.2    Clark, O.H.3    Woeber, K.A.4    Hawkins, R.5    Greenspan, F.S.6
  • 47
    • 47549109967 scopus 로고    scopus 로고
    • Rosiglitazone effect on radioiodine uptake in thyroid carcinoma patients with high thyroglobulin but negative total body scan: a correlation with the expression of peroxisome proliferator-activated receptor-gamma
    • Tepmongkol S, Keelawat S, Honsawek S, Ruangvejvorachai P. Rosiglitazone effect on radioiodine uptake in thyroid carcinoma patients with high thyroglobulin but negative total body scan: a correlation with the expression of peroxisome proliferator-activated receptor-gamma. Thyroid. 2008; 18: 697-704.
    • (2008) Thyroid , vol.18 , pp. 697-704
    • Tepmongkol, S.1    Keelawat, S.2    Honsawek, S.3    Ruangvejvorachai, P.4
  • 48
    • 33747586309 scopus 로고    scopus 로고
    • Enhanced radioiodine uptake in a patient with poorly differentiated papillary thyroid cancer after treatment with rosiglitazone
    • Elias AN, Lizotte P. Enhanced radioiodine uptake in a patient with poorly differentiated papillary thyroid cancer after treatment with rosiglitazone. Clin Nucl Med. 2006; 31: 517-9.
    • (2006) Clin Nucl Med. , vol.31 , pp. 517-519
    • Elias, A.N.1    Lizotte, P.2
  • 49
    • 79959264341 scopus 로고    scopus 로고
    • Redifferentiation therapy with rosiglitazone in a case of differentiated thyroid cancer with pulmonary metastases and absence of radioiodine uptake
    • Elola M, Yoldi A, Emparanza JI, Matteucci T, Bilbao I, Goena M. Redifferentiation therapy with rosiglitazone in a case of differentiated thyroid cancer with pulmonary metastases and absence of radioiodine uptake. Rev Esp Med Nucl. 2011; 30: 241-3.
    • (2011) Rev Esp Med Nucl. , vol.30 , pp. 241-243
    • Elola, M.1    Yoldi, A.2    Emparanza, J.I.3    Matteucci, T.4    Bilbao, I.5    Goena, M.6
  • 50
    • 33646149656 scopus 로고    scopus 로고
    • Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1
    • Copland JA, Marlow LA, Kurakata S, Fujiwara K, Wong AK, Kreinest PA, et al. Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1. Oncogene. 2006; 25: 2304-17.
    • (2006) Oncogene , vol.25 , pp. 2304-2317
    • Copland, J.A.1    Marlow, L.A.2    Kurakata, S.3    Fujiwara, K.4    Wong, A.K.5    Kreinest, P.A.6
  • 53
    • 79960179069 scopus 로고    scopus 로고
    • Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population
    • Ahmed M, Barbachano Y, Riddell A, Hickey J, Newbold KL, Viros A, et al. Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population. Eur J Endocrinol. 2011; 165: 315-22.
    • (2011) Eur J Endocrinol , vol.165 , pp. 315-322
    • Ahmed, M.1    Barbachano, Y.2    Riddell, A.3    Hickey, J.4    Newbold, K.L.5    Viros, A.6
  • 54
    • 79953249278 scopus 로고    scopus 로고
    • Response to sorafenib at a low dose in patients with radioiodine-refractory pulmonary metastases from papillary thyroid carcinoma
    • Chen L, Shen Y, Luo Q, Yu Y, Lu H, Zhu R. Response to sorafenib at a low dose in patients with radioiodine-refractory pulmonary metastases from papillary thyroid carcinoma. Thyroid. 2011; 21: 119-24.
    • (2011) Thyroid , vol.21 , pp. 119-124
    • Chen, L.1    Shen, Y.2    Luo, Q.3    Yu, Y.4    Lu, H.5    Zhu, R.6
  • 55
    • 72949106263 scopus 로고    scopus 로고
    • Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma
    • Hoftijzer H, Heemstra KA, Morreau H, Stokkel MP, Corssmit EP, Gelderblom H, et al. Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. Eur J Endocrinol. 2009; 161: 923-31.
    • (2009) Eur J Endocrinol , vol.161 , pp. 923-931
    • Hoftijzer, H.1    Heemstra, K.A.2    Morreau, H.3    Stokkel, M.P.4    Corssmit, E.P.5    Gelderblom, H.6
  • 56
    • 77954476036 scopus 로고    scopus 로고
    • Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M.D. Anderson experience
    • Cabanillas ME, Waguespack SG, Bronstein Y, Williams MD, Feng L, Hernandez M, et al. Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. J Clin Endocrinol Metab. 2010; 95: 2588-95.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2588-2595
    • Cabanillas, M.E.1    Waguespack, S.G.2    Bronstein, Y.3    Williams, M.D.4    Feng, L.5    Hernandez, M.6
  • 57
    • 50649095801 scopus 로고    scopus 로고
    • Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study
    • Cohen EE, Rosen LS, Vokes EE, Kies MS, Forastiere AA, Worden FP, et al. Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study. J Clin Oncol. 2008; 26: 4708-13.
    • (2008) J Clin Oncol , vol.26 , pp. 4708-4713
    • Cohen, E.E.1    Rosen, L.S.2    Vokes, E.E.3    Kies, M.S.4    Forastiere, A.A.5    Worden, F.P.6
  • 59
    • 77957359933 scopus 로고    scopus 로고
    • Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study
    • Bible KC, Suman VJ, Molina JR, Smallridge RC, Maples WJ, Menefee ME, et al. Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study. Lancet Oncol. 2010; 11: 962-72.
    • (2010) Lancet Oncol. , vol.11 , pp. 962-972
    • Bible, K.C.1    Suman, V.J.2    Molina, J.R.3    Smallridge, R.C.4    Maples, W.J.5    Menefee, M.E.6


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