A model for dynamics of primer extension by eukaryotic DNA primase

European Biophysics Journal

Volumn 40, Issue 10, 2011, Pages 1157-1165

  Xie, Ping ^a  

^a INSTITUTE OF PHYSICS   (China)

Author keywords

DNA primase; Model; Primer synthesis

Indexed keywords

DNA; DNA PRIMASE; NUCLEOTIDE; RNA; RNA PRIMERS;

ARTICLE; BIOLOGICAL MODEL; BIOSYNTHESIS; ENZYMOLOGY; EUKARYOTE; GENETICS; METABOLISM; PROTEIN SUBUNIT;

DNA; DNA PRIMASE; EUKARYOTA; MODELS, BIOLOGICAL; NUCLEOTIDES; PROTEIN SUBUNITS; RNA;

EUKARYOTA;

EID: 82755182709     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-011-0746-8     Document Type: Article

References (24)

1. Arezi B, Kuchta RD (2000) Eucaryotic DNA primase. Trends Biochem Sci 25:572-576
2. Arezi B, Kirk BW, Copeland WC, Kuchta RD (1999) Interactions of DNA with human DNA primase monitored with photoactivatable cross-linking agents: implications for the role of the p58 subunit. Biochemistry 38:12899-12907
3. Corn JE, Berger JM (2006) Regulation of bacterial priming and daughter strand synthesis through helicase-primase interactions. Nucleic Acids Res 34:4082-4088 (Pubitemid 44542187)
4. Cotterill S, Chui G, Lehman IR (1987) DNA polymerase-primase from embryos of Drosophila melanogaster. J Biol Chem 262:16105-16108
5. Fox RF, Choi MH (2001) Rectified Brownian motion and kinesin motion along microtubules. Phys Rev E 63:051901
6. Frick DN, Richardson CC (2001) DNA primases. Ann Rev Biochem 70:39-80 (Pubitemid 32662205)
7. Goulian M, Heard CJ (1989) Intact DNA polymerase a/primase from mouse cells. J Biol Chem 264:19407-19415
8. Hamdan SM, Richardson CC (2009) Motors, switches, and contacts in the replisome. Annu Rev Biochem 78:205-243
9. Kaguni LS, Rossignol J-M, Conaway GR, Banks GR, Lehman IR (1983) Association of DNA primase with ß/γ subunits of DNA polymerase a from Drosophila melanogaster embryos. J Biol Chem 258:9037-9039
10. Kirk BW, Harrington C, Perrino FW, Kuchta RD (1997) Eucaryotic DNA primase does not prefer to synthesize primers at pyrimidine rich DNA sequences when nucleoside triphosphates are present at concentrations found in whole cells. Biochemistry 36:6725-6731 (Pubitemid 27242331)
11. Kuchta RD, Stengel G (2010) Mechanism and evolution of DNA primases. Biochim Biophys Acta 1804:1180-1189
12. Kuchta RD, Reid B, Chang LMS (1990) DNA primase: processivity and the primase to polymerase alpha activity switch. J Biol Chem 265:16158-16165
13. Lehman IR, Kaguni LS (1989) DNA polymerase a. J Biol Chem 264:4265-4267
14. Mogilner A, Mange M, Baskin RJ (1998) Motion ofmolecular motor ratcheted by internal fluctuations and protein friction. Phys Lett A 237:297-306 (Pubitemid 128392453)
15. Schneider A, Smith RWP, Kautz AR, Weisshart K, Grosse F, Nasheuer H-P (1998) Primase activity of human DNA polymer- ase a-primase. J Biol Chem 273:21608-21615 (Pubitemid 28405331)
16. Sheaff R, Kuchta RD (1993) The mechanism of calf thymus DNA primase: slow initiation, rapid polymerization and intelligent termination. Biochemistry 32:3027-3037 (Pubitemid 23110145)
17. Sheaff R, Kuchta RD, Ilsley D (1994) Calf thymus DNA polymerase a-primase: ''communication'' and primer-template movement between the two active sites. Biochemistry 33:2247-2254 (Pubitemid 24099624)
18. Wong JH, Fiala KA, Suo Z, Ling H (2008) Snapshots of a Y-family DNA polymerase in replication: substrate-induced conforma- tional transitions and implications for fidelity of Dpo4. J Mol Biol 379:317-330
19. Xie P (2008) Stepping behavior of two-headed kinesin motors. Biochim Biophys Acta Bioenergetics 1777:1195-1202
20. Xie P (2009) A possible mechanism of processive nucleotide and repeat additions by the telomerase. Bio Systems 97:168-178
21. Xie P (2010) A modified model for translocation events ofprocessive nucleotide and repeat additions by the recombinant telomerase. Biophys Chem 153:83-96
22. Xie P (2011)A model for the dynamics of mammalian family X DNA polymerases. J Theor Biol 277:111-122
23. Xie P, Sayers JR (2011) A model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modes. Plos One 6:e16213
24. Zerbe LK, Kuchta RD (2002) The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting. Biochemistry 41:4891-4900 (Pubitemid 34298656)