Age-related changes in expression of CTL2/SLC44A2 and its isoforms in the mouse inner ear

Hearing Research

Volumn 282, Issue 1-2, 2011, Pages 63-68

  Beyer, Lisa A ^a   Galano, Maria M ^a   Nair, Thankam S ^a   Kommareddi, Pavan K ^a   Sha, Su Hua ^a,b   Raphael, Yehoash ^a   Carey, Thomas E ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GLYCOPROTEIN; PROTEIN CTL2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COCHLEA; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO DEVELOPMENT; EXON; HAIR CELL; HUMAN; INNER EAR; INNER EAR DEVELOPMENT; MOUSE; NONHUMAN; ORGANOGENESIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SENSORY NERVE CELL; UTRICLE;

AGE FACTORS; AGING; ANIMALS; EAR, INNER; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED CBA; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 82755177957     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2011.09.004     Document Type: Article

References (23)

1. Abrashkin K.A., Izumikawa M., Miyazawa T., Wang C.H., Crumling M.A., Swiderski D.L., et al. The fate of outer hair cells after acoustic or ototoxic insults. Hear Res. 2006, 218(1-2):20-29.
2. Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 1999, 284(5415):770-776.
3. Batts S.A., Shoemaker C.R., Raphael Y. Notch signaling and Hes labeling in the normal and drug-damaged organ of Corti. Hear Res. 2009, 249(1-2):15-22.
4. Brooker R., Hozumi K., Lewis J. Notch ligands with contrasting functions: jagged1 and Delta1 in the mouse inner ear. Development 2006, 133(7):1277-1286.
5. Disher M.J., Ramakrishnan A., Nair T.S., Miller J.M., Telian S.A., Arts H.A., et al. Human autoantibodies and monoclonal antibody KHRI-3 bind to a phylogenetically conserved inner-ear-supporting cell antigen. Ann. N. Y Acad. Sci. 1997, 830:253-265.
6. Hartman B.H., Basak O., Nelson B.R., Taylor V., Bermingham-McDonogh O., Reh T.A. Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea. J. Assoc. Res. Otolaryngol. 2009, 10(3):321-340.
7. Kelly M.C., Chen P. Development of form and function in the mammalian cochlea. Curr. Opin. Neurobiol. 2009, 19(4):395-401.
8. Kiernan A.E., Ahituv N., Fuchs H., Balling R., Avraham K.B., Steel K.P., et al. The Notch ligand Jagged1 is required for inner ear sensory development. Proc. Natl. Acad. Sci. U S A 2001, 98(7):3873-3878.
9. Kommareddi P.K., Nair T.S., Raphael Y., Telian S.A., Kim A.H., Arts H.A., et al. Cochlin isoforms and their interaction with CTL2 (SLC44A2) in the inner ear. J. Assoc. Res. Otolaryngol. 2007, 8(4):435-446.
10. Kommareddi P.K., Nair T.S., Vallurupalli M., Telian S.A., Arts H.A., El-Kashlan H.K., et al. Autoantibodies to recombinant human CTL2 in autoimmune hearing loss. Laryngoscope 2009, 119(5):924-932.
11. Kommareddi P.K., Nair T.S., Thang L.V., Galano M.M., Babu E., Ganapathy V., et al. Isoforms, expression, glycosylation, and tissue distribution of CTL2/SLC44A2. Protein J. 2010.
12. Nair T.S., Raphael Y., Dolan D.F., Parrett T.J., Perlman L.S., Brahmbhatt V.R., et al. Monoclonal antibody induced hearing loss. Hear Res. 1995, 83(1-2):101-113.
13. Nair T.S., Prieskorn D.M., Miller J.M., Mori A., Gray J., Carey T.E. In vivo binding and hearing loss after intracochlear infusion of KHRI-3 antibody. Hear Res. 1997, 107(1-2):93-101.
14. Nair T.S., Prieskorn D.M., Miller J.M., Dolan D.F., Raphael Y., Carey T.E. KHRI-3 monoclonal antibody-induced damage to the inner ear: antibody staining of nascent scars. Hear Res. 1999, 129(1-2):50-60.
15. Nair T.S., Kozma K.E., Hoefling N.L., Kommareddi P.K., Ueda Y., Gong T.W., et al. Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss. J. Neurosci. 2004, 24(7):1772-1779.
16. O'Regan S., Traiffort E., Ruat M., Cha N., Compaore D., Meunier F.M. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. Proc. Natl. Acad. Sci. U S A 2000, 97(4):1835-1840.
17. O'Regan S., Meunier F.M. Selection and characterization of the choline transport mutation suppressor from Torpedo electric lobe, CTL1. Neurochem. Res. 2003, 28(3-4):551-555.
18. Raphael Y. Cochlear pathology, sensory cell death and regeneration. Br. Med. Bull. 2002, 63:25-38.
19. Sha S.H., Kanicki A., Dootz G., Talaska A.E., Halsey K., Dolan D., et al. Age-related auditory pathology in the CBA/J mouse. Hear Res. 2008, 243(1-2):87-94.
20. Sha S.H., Chen F.Q., Schacht J. PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse. Hear Res. 2010, 264(1-2):86-92.
21. Traiffort E., Ruat M., O'Regan S., Meunier F.M. Molecular characterization of the family of choline transporter-like proteins and their splice variants. J. Neurochem. 2005, 92(5):1116-1125.
22. Wang G.P., Chatterjee I., Batts S.A., Wong H.T., Gong T.W., Gong S.S., et al. Notch signaling and Atoh1 expression during hair cell regeneration in the mouse utricle. Hear Res. 2010, 267(1-2):61-70.
23. Zajic G., Nair T.S., Ptok M., Van Waes C., Altschuler R.A., Schacht J., et al. Monoclonal antibodies to inner ear antigens: I. Antigens expressed by supporting cells of the guinea pig cochlea. Hear Res. 1991, 52(1):59-71.