Mass dose effects and in vivo affinity in brain PET receptor studies - a study of cerebral 5-HT 4 receptor binding with [ 11C]SB207145

Nuclear Medicine and Biology

Volumn 38, Issue 8, 2011, Pages 1085-1091

  Madsen, Karine ^a   Marner, Lisbeth ^a   Haahr, Mette ^a   Gillings, Nic ^a   Knudsen, Gitte M ^a  

^a Rigshospitalet   (Denmark)

Author keywords

Human; Injected mass; K D; Mass dose; Occupancy; PET

Indexed keywords

RADIOLIGAND; SB 207145; SB 207145 C 11; SEROTONIN 4 RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG RECEPTOR BINDING; FEMALE; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; MALE; MATHEMATICAL COMPUTING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; RECEPTOR AFFINITY; RECEPTOR OCCUPANCY;

ADULT; BRAIN; CARBON RADIOISOTOPES; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MIDDLE AGED; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; RECEPTORS, SEROTONIN, 5-HT4; REPRODUCIBILITY OF RESULTS; YOUNG ADULT;

EID: 82655181899     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2011.04.006     Document Type: Article

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