High dose methylprednisolone counteracts the negative effects of rocuronium on diaphragm function

Intensive Care Medicine

Volumn 37, Issue 11, 2011, Pages 1865-1872

  Maes, Karen ^a   Testelmans, Dries ^a   Thomas, Debby ^a   Decramer, Marc ^a   Gayan Ramirez, Ghislaine ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Mechanical ventilation; Methylprednisolone; Rocuronium

Indexed keywords

ACTIN; CALPAIN; CASPASE 3; MESSENGER RNA; METHYLPREDNISOLONE; MUSCLE RING FINGER 1 PROTEIN; ROCURONIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; ARTIFICIAL VENTILATION; ATTENUATION; CONTROLLED STUDY; DIAPHRAGM DISEASE; DIAPHRAGM MOVEMENT; DRUG EFFICACY; DRUG MEGADOSE; GASTROCNEMIUS MUSCLE; LOADING DRUG DOSE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN DEGRADATION; RAT;

ANDROSTANOLS; ANIMALS; DIAPHRAGM; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOCORTICOIDS; METHYLPREDNISOLONE; NEUROMUSCULAR NONDEPOLARIZING AGENTS; RANDOM ALLOCATION; RATS; RATS, WISTAR; RESPIRATION, ARTIFICIAL;

EID: 82555191035     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-011-2337-7     Document Type: Article

References (41)

1. MJ Murray J Cowen H DeBlock B Erstad AW Gray Jr AN Tescher WT McGee RC Prielipp G Susla J Jacobi SA Nasraway Jr PD Lumb 2002 Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient Crit Care Med 30 142 156 11902255 10.1097/00003246-200201000-00021 1:CAS:528:DC%2BD38XhtVyluro%3D (Pubitemid 34112189)
2. CF Bolton 2005 Neuromuscular manifestations of critical illness Muscle Nerve 32 140 163 15825186 10.1002/mus.20304 (Pubitemid 41061488)
3. M Hirano BR Ott EC Raps C Minetti L Lennihan NP Libbey E Bonilla AP Hays 1992 Acute quadriplegic myopathy: a complication of treatment with steroids, nondepolarizing blocking agents, or both Neurology 42 2082 2087 1436516 1:STN:280:DyaK3s%2Fmtl2jsA%3D%3D
4. D Lacomis MJ Giuliani A Van Cott DJ Kramer 1996 Acute myopathy of intensive care: clinical, electromyographic, and pathological aspects Ann Neurol 40 645 654 8871585 10.1002/ana.410400415 1:STN:280:DyaK2s%2FisFeqtw%3D%3D (Pubitemid 26357890)
5. JP Lefaucheur T Nordine P Rodriguez L Brochard 2006 Origin of ICU acquired paresis determined by direct muscle stimulation J Neurol Neurosurg Psychiatry 77 500 506 16306155 10.1136/jnnp.2005.070813
6. JW Leatherman WL Fluegel WS David SF Davies C Iber 1996 Muscle weakness in mechanically ventilated patients with severe asthma Am J Respir Crit Care Med 153 1686 1690 8630621 1:STN:280:DyaK283htVahsg%3D%3D (Pubitemid 26141357)
7. O Friedrich 2006 Critical illness myopathy: what is happening? Curr Opin Clin Nutr Metab Care 9 403 409 16778569 10.1097/01.mco.0000232900.59168.a0 1:CAS:528:DC%2BD28Xot1ahsLc%3D (Pubitemid 44097810)
8. NA Behbehani F Al Mane Y D'yachkova P Pare JM FitzGerald 1999 Myopathy following mechanical ventilation for acute severe asthma: the role of muscle relaxants and corticosteroids Chest 115 1627 1631 10378560 10.1378/chest.115.6. 1627 1:CAS:528:DyaK1MXktFGitLc%3D (Pubitemid 29275656)
9. S Nava G Gayan-Ramirez H Rollier A Bisschop R Dom V de Bock M Decramer 1996 Effects of acute steroid administration on ventilatory and peripheral muscles in rats Am J Respir Crit Care Med 153 1888 1896 8665051 1:STN:280:DyaK283nvFOkug%3D%3D (Pubitemid 26187916)
10. D Testelmans K Maes P Wouters N Gosselin K Deruisseau S Powers R Sciot M Decramer G Gayan-Ramirez 2006 Rocuronium exacerbates mechanical ventilation-induced diaphragm dysfunction in rats Crit Care Med 34 3018 3023 17012910 1:CAS:528:DC%2BD28Xht1CgtLnM (Pubitemid 44808747)
11. K Maes D Testelmans P Cadot K Deruisseau SK Powers M Decramer G Gayan-Ramirez 2008 Effects of acute administration of corticosteroids during mechanical ventilation on rat diaphragm Am J Respir Crit Care Med 178 1219 1226 18849500 10.1164/rccm.200702-296OC 1:CAS:528:DC%2BD1MXmslyrsw%3D%3D
12. G Gayan-Ramirez K de Paepe P Cadot M Decramer 2003 Detrimental effects of short-term mechanical ventilation on diaphragm function and IGF-I mRNA in rats Intensive Care Med 29 825 833 12682716 (Pubitemid 36609577)
13. PN Dekhuijzen G Gayan-Ramirez V de Bock R Dom M Decramer 1993 Triamcinolone and prednisolone affect contractile properties and histopathology of rat diaphragm differently J Clin Invest 92 1534 1542 8376603 10.1172/JCI116732 1:CAS:528:DyaK2cXns1M%3D (Pubitemid 23273934)
14. SK Powers RA Shanely JS Coombes TJ Koesterer M McKenzie D Van Gammeren M Cicale SL Dodd 2002 Mechanical ventilation results in progressive contractile dysfunction in the diaphragm J Appl Physiol 92 1851 1858 11960933 (Pubitemid 34666410)
15. CS Sassoon VJ Caiozzo A Manka GC Sieck 2002 Altered diaphragm contractile properties with controlled mechanical ventilation J Appl Physiol 92 2585 2595 12015377 (Pubitemid 34666388)
16. G Hermans A Agten D Testelmans M Decramer G Gayan-Ramirez 2010 Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study Crit Care 14 R127 20594319 10.1186/cc9094
17. S Jaber BJ Petrof B Jung G Chanques JP Berthet C Rabuel H Bouyabrine P Courouble C Koechlin-Ramonatxo M Sebbane T Similowski V Scheuermann A Mebazaa X Capdevila D Mornet J Mercier A Lacampagne A Philips S Matecki 2011 Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans Am J Respir Crit Care Med 183 364 371 20813887 10.1164/rccm.201004-0670OC 1:CAS:528:DC%2BC3MXivFWhtbY%3D
18. F Laghi MJ Harrison MJ Tobin 1996 Comparison of magnetic and electrical phrenic nerve stimulation in assessment of diaphragmatic contractility J Appl Physiol 80 1731 1742 8727561 10.1063/1.362972 1:STN:280:DyaK28zitleqsQ%3D%3D (Pubitemid 26143924)
19. AC Watson PD Hughes HM Louise N Hart RJ Ware J Wendon M Green J Moxham 2001 Measurement of twitch transdiaphragmatic, esophageal, and endotracheal tube pressure with bilateral anterolateral magnetic phrenic nerve stimulation in patients in the intensive care unit Crit Care Med 29 1325 1331 11445679 10.1097/00003246-200107000-00005 1:STN:280:DC%2BD3MzptVymsw%3D%3D (Pubitemid 32641792)
20. A Arroliga F Frutos-Vivar J Hall A Esteban C Apezteguia L Soto A Anzueto 2005 Use of sedatives and neuromuscular blockers in a cohort of patients receiving mechanical ventilation Chest 128 496 506 16100131 10.1378/chest.128.2. 496 (Pubitemid 41140473)
21. S Bercker S Weber-Carstens M Deja C Grimm S Wolf F Behse T Busch KJ Falke U Kaisers 2005 Critical illness polyneuropathy and myopathy in patients with acute respiratory distress syndrome Crit Care Med 33 711 715 15818093 10.1097/01.CCM.0000157969.46388.A2
22. R Amaya-Villar J Garnacho-Montero JL Garcia-Garmendia J Madrazo-Osuna MC Garnacho-Montero R Luque C Ortiz-Leyba 2005 Steroid-induced myopathy in patients intubated due to exacerbation of chronic obstructive pulmonary disease Intensive Care Med 31 157 161 15580474 10.1007/s00134-004-2509-9 (Pubitemid 40174297)
23. J Bednarik P Vondracek L Dusek E Moravcova I Cundrle 2005 Risk factors for critical illness polyneuromyopathy J Neurol 252 343 351 15791390 10.1007/s00415-005-0654-x 1:STN:280:DC%2BD2M7ntlCgtg%3D%3D (Pubitemid 40562168)
24. MA de Letter PI Schmitz LH Visser FA Verheul RL Schellens DA Op de Coul FG van der Meche 2001 Risk factors for the development of polyneuropathy and myopathy in critically ill patients Crit Care Med 29 2281 2286 11801825 10.1097/00003246-200112000-00008 (Pubitemid 34038159)
25. G Van den Berghe K Schoonheydt P Becx F Bruyninckx PJ Wouters 2005 Insulin therapy protects the central and peripheral nervous system of intensive care patients Neurology 64 1348 1353 15851721 10.1212/01.WNL.0000158442.08857.FC (Pubitemid 40570499)
26. JV Campellone D Lacomis DJ Kramer AC Van Cott MJ Giuliani 1998 Acute myopathy after liver transplantation Neurology 50 46 53 9443456 1:STN:280:DyaK1c7gtlKqsQ%3D%3D (Pubitemid 128722716)
27. JB De T Sharshar JP Lefaucheur FJ Authier I Durand-Zaleski M Boussarsar C Cerf E Renaud F Mesrati J Carlet JC Raphael H Outin S Bastuji-Garin 2002 Paresis acquired in the intensive care unit: a prospective multicenter study JAMA 288 2859 2867 10.1001/jama.288.22.2859 (Pubitemid 35425072)
28. MS Herridge AM Cheung CM Tansey A Matte-Martyn N Diaz-Granados F Al-Saidi AB Cooper CB Guest CD Mazer S Mehta TE Stewart A Barr D Cook AS Slutsky 2003 One-year outcomes in survivors of the acute respiratory distress syndrome N Engl J Med 348 683 693 12594312 10.1056/NEJMoa022450 (Pubitemid 36237037)
29. G Hermans A Wilmer W Meersseman I Milants PJ Wouters H Bobbaers F Bruyninckx G Van den Berghe 2007 Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit Am J Respir Crit Care Med 175 480 489 17138955 10.1164/rccm.200605- 665OC 1:CAS:528:DC%2BD2sXjtlKqsLg%3D (Pubitemid 46354252)
30. J Garnacho-Montero J Madrazo-Osuna JL Garcia-Garmendia C Ortiz-Leyba FJ Jimenez-Jimenez A Barrero-Almodovar MC Garnacho-Montero MR Moyano-Del-Estad 2001 Critical illness polyneuropathy: risk factors and clinical consequences. A cohort study in septic patients Intensive Care Med 27 1288 1296 11511941 10.1007/s001340101009 1:STN:280:DC%2BD3Mvms1Kgug%3D%3D (Pubitemid 32758926)
31. S Soltesz T Mencke M Stunz C Diefenbach S Ziegeler GP Molter 2009 Attenuation of a rocuronium-induced neuromuscular block in patients receiving prednisolone Acta Anaesthesiol Scand 53 443 448 19317861 10.1111/j.1399-6576. 2009.01908.x 1:CAS:528:DC%2BD1MXotFSjt7k%3D
32. L Gutmann D Blumenthal L Gutmann SS Schochet 1996 Acute type II myofiber atrophy in critical illness Neurology 46 819 821 8618690 1:STN:280: DyaK287ntlKquw%3D%3D (Pubitemid 26099654)
33. 2+-activated and ATP-ubiquitin-dependent proteinases in the unweighted rat soleus muscle Biochem J 316 Pt 1 65 72 8645234 1:CAS:528:DyaK28Xjt1Gjsbo%3D
34. K Maes D Testelmans S Powers M Decramer G Gayan-Ramirez 2007 Leupeptin inhibits ventilator-induced diaphragm dysfunction in rats Am J Respir Crit Care Med 175 1134 1138 17379854 10.1164/rccm.200609-1342OC 1:CAS:528: DC%2BD2sXnt1Sqs74%3D (Pubitemid 46855454)
35. RA Shanely MA Zergeroglu SL Lennon T Sugiura T Yimlamai D Enns A Belcastro SK Powers 2002 Mechanical ventilation-induced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activity Am J Respir Crit Care Med 166 1369 1374 12421745 10.1164/rccm.200202-088OC (Pubitemid 35292704)
36. SN Hussain M Mofarrahi I Sigala HC Kim T Vassilakopoulos F Maltais I Bellenis R Chaturvedi SB Gottfried P Metrakos G Danialou S Matecki S Jaber BJ Petrof P Goldberg 2010 Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy Am J Respir Crit Care Med 182 1377 1386 20639440 10.1164/rccm.201002-0234OC 1:CAS:528:DC%2BC3MXltlKisw%3D%3D
37. S Levine T Nguyen N Taylor ME Friscia MT Budak P Rothenberg J Zhu R Sachdeva S Sonnad LR Kaiser NA Rubinstein SK Powers JB Shrager 2008 Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans N Engl J Med 358 1327 1335 18367735 10.1056/NEJMoa070447 1:CAS:528:DC%2BD1cXjvFOnsLk%3D (Pubitemid 351468409)
38. S Levine C Biswas J Dierov R Barsotti JB Shrager T Nguyen S Sonnad JC Kucharchzuk LR Kaiser S Singhal MT Budak 2011 Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse Am J Respir Crit Care Med 183 483 490 20833824 10.1164/rccm.200910-1487OC 1:CAS:528:DC%2BC3MXjslCkurk%3D
39. H Stibler L Edstrom K Ahlbeck S Remahl T Ansved 2003 Electrophoretic determination of the myosin/actin ratio in the diagnosis of critical illness myopathy Intensive Care Med 29 1515 1527 12915938 10.1007/s00134-003-1894-9 (Pubitemid 37153596)
40. E Koerts-De Lang AM Schols EF Wouters G Gayan-Ramirez M Decramer 1998 Contractile properties and histochemical characteristics of the rat diaphragm after prolonged triamcinolone treatment and nutritional deprivation J Muscle Res Cell Motil 19 549 555 9682141 10.1023/A:1005364627467 1:CAS:528: DyaK1cXltFCqtL0%3D (Pubitemid 28319084)
41. K Maes A Agten A Smuder SK Powers M Decramer G Gayan-Ramirez 2010 Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered Respir Res 11 178 183 21156051 10.1186/1465-9921-11-178 1:CAS:528:DC%2BC3cXhs1amsL3F