Mutations in the gene encoding C8orf38 block complex i assembly by inhibiting production of the mitochondria-encoded subunit ND1

Journal of Molecular Biology

Volumn 414, Issue 3, 2011, Pages 413-426

  McKenzie, Matthew ^a   Tucker, Elena J ^b,c   Compton, Alison G ^b   Lazarou, Michael ^d,e   George, Christa ^e   Thorburn, David R ^b,c   Ryan, Michael T ^e,f  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^e LA TROBE UNIVERSITY   (Australia)

^f LA TROBE UNIVERSITY   (Australia)

Author keywords

blue native PAGE; complex I assembly factor; Leigh syndrome; mitochondria; mtDNA encoded translation

Indexed keywords

MITOCHONDRIAL DNA; PROTEIN; PROTEIN C8ORF38; PROTEIN SUBUNIT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; FIBROBLAST; GENE MUTATION; HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN SYNTHESIS;

EID: 82555168324     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.10.012     Document Type: Article

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