Reverse-transcription polymerase chain reaction/pyrosequencing to characterize neuraminidase H275 residue of influenza A 2009 H1N1 virus for rapid and specific detection of the viral oseltamivir resistance marker in a clinical laboratory

Diagnostic Microbiology and Infectious Disease

Volumn 71, Issue 4, 2011, Pages 396-402

  Bao, Jian R ^a   Huard, Thomas K ^a   Piscitelli, Arelis E ^a   Tummala, Praveena R ^a   Aleemi, Virginia E ^a   Coon, Stephanie L ^a   Master, Ronald N ^a   Lewinski, Michael A ^b   Clark, Richard B ^a  

^a QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2009 H1N1 virus; H275Y (H274Y) mutation; Oseltamivir resistance; Pyrosequencing

Indexed keywords

NEURAMINIDASE H275; OSELTAMIVIR; PERAMIVIR; UNCLASSIFIED DRUG; VIRUS SIALIDASE;

2009 H1N1 INFLUENZA; ADULT; AMPLICON; ANTIFUNGAL RESISTANCE; ARTICLE; CLINICAL LABORATORY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; GENE MUTATION; HUMAN; INFLUENZA VIRUS A H1N1; MALE; NONHUMAN; PRIORITY JOURNAL; PYROSEQUENCING; REACTION TIME; RESIDUE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; VIRUS CHARACTERIZATION; VIRUS DETECTION; VIRUS STRAIN;

ADULT; ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; NEURAMINIDASE; OSELTAMIVIR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

EID: 82555165804     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2011.09.003     Document Type: Article

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