Calcium and vitamin D controversies

Rheumatic Disease Clinics of North America

Volumn 37, Issue 3, 2011, Pages 351-363

  Silver, David S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b OMC Clinical Research Center   (United States)

Author keywords

Calcium; Controversy; Osteoporosis; Vitamin D

Indexed keywords

CALCIFEDIOL; CALCITONIN; CALCITRIOL; CALCIUM; COLECALCIFEROL; ERGOCALCIFEROL; PARATHYROID HORMONE; PLACEBO; VITAMIN D; VITAMIN D RECEPTOR;

BLOOD VESSEL CALCIFICATION; BONE DENSITY; CALCIUM BLOOD LEVEL; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; CORONARY ARTERY DISEASE; DIETARY INTAKE; DISEASE ASSOCIATION; DRUG MEGADOSE; FALLING; FOOD COMPOSITION; FRACTURE; HEART INFARCTION; HIGH RISK POPULATION; HUMAN; IMMUNOMODULATION; INSULIN DEPENDENT DIABETES MELLITUS; MALIGNANT NEOPLASTIC DISEASE; MORTALITY; MULTIPLE SCLEROSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRITIONAL REQUIREMENT; OBSERVATIONAL STUDY; OSSIFICATION; OSTEOLYSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; REVIEW; RISK BENEFIT ANALYSIS; RISK REDUCTION; SECONDARY HYPERPARATHYROIDISM; VITAMIN D DEFICIENCY; VITAMIN D METABOLISM; VITAMIN SUPPLEMENTATION;

AGED; AUTOIMMUNE DISEASES; BONE DENSITY CONSERVATION AGENTS; CALCIUM; CARDIOVASCULAR DISEASES; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MIDDLE AGED; NEOPLASMS; OSTEOPOROSIS, POSTMENOPAUSAL; PRACTICE GUIDELINES AS TOPIC; RISK FACTORS; VITAMIN D;

EID: 82455205747     PISSN: 0889857X     EISSN: 15583163     Source Type: Journal    
DOI: 10.1016/j.rdc.2011.07.005     Document Type: Review

References (54)

1. Oren Y., Shapira Y., Agmon-Levin N., et al. Vitamin D insufficiency in a sunny environment: a demographic and seasonal analysis. Isr Med Assoc J 2010, 12:751-756.
2. Binkley N., Ramamurthy R., Krueger D. Low vitamin D status: definition, prevalence, consequences, and correction. Endocrinol Metab Clin North Am 2010, 39:287-301.
3. Arabi A., El Rassi R., El-Haji Fuleihan G. Hypovitaminosis D in developing countries-prevalence, risk factors and outcomes. Nat Rev Endocrinol 2010, 6:550-561.
4. Bordelon P., Ghetu M., Langan R. Recognition and management of vitamin D deficiency. Am Fam Physician 2009, 80:841-846.
5. Thacher T., Clarke B. Vitamin D insufficiency. Mayo Clin Proc 2011, 86:50-60.
6. Heaney R. Vitamin D in health and disease. Clin J Am Soc Nephrol 2008, 3:1535-1541.
7. Cranney A., Horsley Y., O'Donnell S., et al. Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep) 2007, (158):1-235.
8. Larrosa M., Gomez A., Casado E., et al. Hypovitaminosis D as a risk factor of hip fracture severity. Osteoporos Int 2011, [Epub ahead of print].
9. Rabenda V., Bruyere O., Reginster J. Relationship between bone mineral density changes and risk of fractures among patients receiving calcium with or without vitamin D supplementation: a meta-regression. Osteoporos Int 2011, 22:893-901.
10. Nurmi-Luthje I., Luthje P., Kaukonen J., et al. Post-fracture prescribed calcium and vitamin D supplements alone or, in females, with concomitant anti-osteoporosis drugs is associated with lower mortality in elderly hip fracture patients: a prospective analysis. Drugs Aging 2009, 26:409-421.
11. Pfeifer M., Begerow B., Minne H., et al. Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals. Osteoporos Int 2009, 20:315-322.
12. Bischoff H., Stahelin H., Dick W., et al. Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res 2003, 18:343-351.
13. Bischoff H., Dawson-Hughes B., Orav J., et al. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomized controlled trials. BMJ 2009, 339:3692.
14. Sanders K., Stuart S., Williamson E., et al. The efficacy of high-dose oral vitamin D3 administered once a year: a randomized, double-blind, placebo-controlled trial (Vital D study) for fall and fractures in older women. Osteoporos Int 2011, 22(Suppl 1):S104.
15. Dietary reference intakes for calcium and vitamin D 2010, Institute of Medicine, Washington, DC.
16. Ross A., Manson J., Abrams S., et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: What clinicians need to know. J Clin Endocrinol Metab 2011, 96:53-58.
17. Van den Bergh J., Bours S., van Geel T., et al. Optimal use of vitamin D when treating osteoporosis. Curr Osteoporos Rep 2011, 9:36-42.
18. Reid I., Avenell I. Evidence-based policy on dietary calcium and vitamin D. J Bone Miner Res 2011, 26:452-454.
19. Heaney R., Holick M. Why the IOM recommendations for vitamin D are deficient. J Bone Miner Res 2011, 26:455-457.
20. Trivedi D., Doll R., Khaw K. Effect on four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: a randomized, double-blind, controlled trial. BMJ 2003, 236:469-474.
21. Dawson-Hughes B. Serum 25-hydroxyvitamin D and functional outcomes in the elderly. Am J Clin Nutr 2008, 88(2):537S-540S.
22. Bolland M., Barber P., Doughty R., et al. Vascular events in healthy older women receiving calcium supplementation: randomized controlled trial. BMJ 2008, 336:262-266.
23. Bolland M., Avenell A., Baron J., et al. Effects of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ 2010, 341:3691-3699.
24. Lappe J., Heaney R. Results may not be generalisable. BMJ 2008, 336:403.
25. Pentti K., Tuppurainen M., Honkanen R., et al. Use of calcium supplements and the risk of coronary heart disease in 52-62-year-old women: the Kuipio Osteoporosis Risk Factor and Prevention Study. Maturitas 2009, 63:73-78.
26. Shah S., Carey I., Harris T., et al. Calcium supplementation, cardiovascular disease and mortality in older women. Pharmacoepidemiol Drug Saf 2010, 19:59-64.
27. Hsu H., Culley N. Effects of dietary calcium on atherosclerosis, aortic calcification, and icterus in rabbits fed a supplemental cholesterol diet. Lipids Health Dis 2006, 5:16.
28. Bhakta M., Bruce C., Messika-Zeitoun D., et al. Oral calcium supplements do not affect the progression of aortic valve calcification or coronary artery calcification. J Am Board Fam Med 2009, 22:610-616.
29. LaCroix A., Kotchen J., Anderson G., et al. Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial. J Gerontol 2009, 64A:559-567.
30. Hsia L., Heiss G., Ren H. Calcium/vitamin D supplementation and cardiovascular events. Circulation 2007, 115:845-852.
31. Yao S., Sucheston L., Millen A., et al. Pretreatment serum concentrations of 25-hydroxyvitamin D and breast cancer prognostic characteristics: a case-control and case-series study. PLoS One 2011, 6:e17251.
32. Garland C., Gorham E., Mohr S., et al. Vitamin D and prevention of breast cancer: pooled analysis. J Steroid Biochem Mol Biol 2007, 103:701-711.
33. Chen P., Hu P., Xie D., et al. Meta-analysis of vitamin D, calcium, and the prevention of breast cancer. Breast Cancer Res Treat 2010, 121:469-477.
34. Gorman E., Garland C., Garland F., et al. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta-analysis. Am J Prev Med 2007, 32:210-216.
35. Touvier M., Chan D., Lau R., et al. Meta-analysis of vitamin D intake, 25-hydroxyvitamin D status, vitamin D receptor polymorphisms and colorectal cancer. Cancer Epidemiol Biomarkers Prev 2011, 20(5):1003-1016.
36. Raimondi S., Johansson H., Maisonneuve P., et al. Review and meta-analysis on vitamin D receptor polymorphisms and cancer risk. Carcinogenesis 2009, 37:1170-1180.
37. Yin L., Grandi N., Raum E., et al. Meta-analysis: circulating vitamin D and ovarian cancer risk. Gynecol Oncol 2011, 121(2):369-375.
38. Choo C., Mamedov A., Chung M., et al. Vitamin D insufficiency is common in patients with nonmetastatic prostate cancer. Nutr Res 2011, 31:21-26.
39. Field S., Newton-Bishop J. Melanoma and vitamin D. Mol Oncol 2011, 5(2):197-214.
40. Bulathsinghala P., Syrigos K., Saif M. Role of vitamin D in the prevention of pancreatic cancer. J Nutr Metab 2011, [Epub ahead of print].
41. Zabiotska L., Gong Z., Wang F., et al. Vitamin D, calcium, and retinol intake, and pancreatic cancer in a population-based case-control study in the San Francisco Bay area. Cancer Causes Control 2011, 22:91-100.
42. Broder A., Tobin J., Putterman C. Disease-specific definitions of vitamin D deficiency need to be established in autoimmune and non-autoimmune chronic diseases: a retrospective comparison of three chronic diseases. Arthritis Res Ther 2010, 12:R191.
43. Guillot X., Semerano L., Saidenberg-Kermanac'h N., et al. Vitamin D and inflammation. Joint Bone Spine 2010, 77:552-557.
44. Marques D., Dantas A., Fragoso T., et al. The importance of vitamin D levels in autoimmune disease. Rev Bras Rheumtol 2010, 50:61-67.
45. Amital H., Szekanecz Z., Szucs G., et al. Serum concentrations of 25-OH vitamin D with systemic lupus erythematosis (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D?. Ann Rheum Dis 2010, 69:1155-1157.
46. Lee Y., Bae S., Choi S., et al. Associations between vitamin D receptor polymorphisms and susceptibility to rheumatoid arthritis and systemic lupus erythematosis: a meta-analysis. Mol Biol Rep 2011, 38(6):3643-3651.
47. Abbasi M., Rezaieyazdi Z., Afshari J., et al. Lack of association of vitamin D receptor gene BsmI polymorphisms in patient with systemic lupus erythematosis. Rheumatol Int 2010, 30:1537-1539.
48. Szodoray P., Tarr T., Bazso A., et al. The immunopathological role of vitamin D in patients with SLE: data from a single centre registry in Hungary. Scand J Rheumatol 2011, 40:122-126.
49. Palomer X., Gonzalez-Clemente J., Blanco-Vaca F., et al. Role of vitamin D in the pathogenesis of type 2 diabetes mellitus. Diabetes Obes Metab 2008, 10:185-197.
50. Takiishi T., Gysemans C., Boullion R., et al. Vitamin D and diabetes. Endocrinol Metab Clin North Am 2010, 39:419-446.
51. Andizzone S., Cassinotti A., Bevilacqua M., et al. Vitamin D and inflammatory bowel disease. Vitam Horm 2011, 86:367-377.
52. Brown A. The role of vitamin D in multiple sclerosis. Ann Pharmacother 2006, 40:1158-1161.
53. De Rezende Pena C., Grillo L., das Chagas Mederios M. Evaluation of 25-hydroxyvitamin D serum levels in patients with fibromyalgia. J Clin Rheumatol 2010, 16:365-369.
54. Armstrong D., Meenegh G.K., Bickle I., et al. Vitamin D deficiency is associated with anxiety and depression in fibromyalgia. Clin Rheumatol 2007, 26:551-554.