Improved periodontal health and cardiovascular risk

Australian Dental Journal

Volumn 56, Issue 4, 2011, Pages 352-357

  Rose Hill, S ^a   Ford, P J ^a   Leishman, S J ^a   Do, H L ^a   Palmer, J E ^a   Heng, N C K ^b   West, M J ^a   Seymour, G J ^a,b   Cullinan, M P ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

cardiovascular disease; cytokines; heat shock protein 60 (HSP60); Periodontal disease; Porphyromonas gingivalis; serum antibodies

Indexed keywords

AUTACOID; BACTERIUM ANTIBODY; CHAPERONIN; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1;

ADULT; ARTICLE; BLOOD; CARDIOVASCULAR DISEASE; CHRONIC PERIODONTITIS; FEMALE; HUMAN; IMMUNOLOGY; MALE; MIDDLE AGED; NONPARAMETRIC TEST; RETROSPECTIVE STUDY; RISK FACTOR;

ADULT; ANTIBODIES, BACTERIAL; CARDIOVASCULAR DISEASES; CHAPERONIN 60; CHRONIC PERIODONTITIS; CYTOKINES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; STATISTICS, NONPARAMETRIC;

EID: 82455198695     PISSN: 00450421     EISSN: 18347819     Source Type: Journal    
DOI: 10.1111/j.1834-7819.2011.01363.x     Document Type: Article

References (30)

1. Cullinan MP, Ford PJ, Seymour GJ,. Periodontal disease and systemic health: current status. Aust Dent J 2009; 54 Suppl 1: S62-S69.
2. Bahekar AA, Singh S, Saha S, Molnar J, Arora R,. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis. Am Heart J 2007; 154: 830-837. (Pubitemid 47632489)
3. Humphrey LL, Fu R, Buckley DI, Freeman M, Helfand M,. Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med 2008; 23: 2079-2086.
4. Tabeta K, Yamazaki K, Hotokezaka H, Yoshie H, Hara K,. Elevated humoral immune response to heat shock protein 60 (hsp60) family in periodontitis patients. Clin Exp Immunol 2000; 120: 285-293. (Pubitemid 30304224)
5. Ford PJ, Gemmell E, Hamlet SM, et al., Cross-reactivity of GroEL antibodies with human heat shock protein 60 and quantification of pathogens in atherosclerosis. Oral Microbiol Immunol 2005; 20: 296-302. (Pubitemid 41208411)
6. Ford P, Gemmell E, Walker P, West M, Cullinan M, Seymour G,. Characterization of heat shock protein-specific T cells in atherosclerosis. Clin Diagn Lab Immunol 2005; 12: 259-267. (Pubitemid 41094450)
7. Seymour GJ, Ford PJ, Cullinan MP, Leishman S, Yamazaki K,. Relationship between periodontal infections and systemic disease. Clin Microbiol Infect 2007; 13 (Suppl 4): 3-10. (Pubitemid 47308185)
8. Ford PJ, Gemmell E, Chan A, et al., Inflammation, heat shock proteins and periodontal pathogens in atherosclerosis: an immunohistologic study. Oral Microbiol Immunol 2006; 21: 206-211. (Pubitemid 44336949)
9. D'Aiuto F, Ready D, Tonetti MS,. Periodontal disease and C-reactive protein-associated cardiovascular risk. J Periodontal Res 2004; 39: 236-241. (Pubitemid 38969606)
10. D'Aiuto F, Parkar M, Andreou G, et al., Periodontitis and systemic inflammation: control of the local infection is associated with a reduction in serum inflammatory markers. J Dent Res 2004; 83: 156-160. (Pubitemid 41713801)
11. Vidal F, Figueredo CM, Cordovil I, Fischer RG,. Periodontal therapy reduces plasma levels of interleukin-6, C-reactive protein, and fibrinogen in patients with severe periodontitis and refractory arterial hypertension. J Periodontol 2009; 80: 786-791.
12. Behle JH, Sedaghatfar MH, Demmer RT, et al., Heterogeneity of systemic inflammatory responses to periodontal therapy. J Clin Periodontol 2009; 36: 287-294.
13. Buhlin K, Hultin M, Norderyd O, et al., Periodontal treatment influences risk markers for atherosclerosis in patients with severe periodontitis. Atherosclerosis 2009; 206: 518-522.
14. Yamazaki K, Ueki-Maruayama K, Honda T, Nakajima T, Seymour GJ,. Effect of periodontal treatment on the serum antibody levels to heat shock proteins. Clin Exp Immunol 2004; 135: 478-482. (Pubitemid 38297150)
15. Scannapieco FA, Dasanayake AP, Chhun N,. Does periodontal therapy reduce the risk for systemic diseases? Dent Clin North Am 2010; 54: 163-181.
16. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497.
17. Bohnstedt S, Cullinan MP, Ford PJ, et al., High antibody levels to P. gingivalis in cardiovascular disease. J Dent Res 2010; 89: 938-942.
18. Gemmell E, Bird PS, Carter CL, Drysdale KE, Seymour GJ,. Effect of Fusobacterium nucleatum on the T and B cell responses to Porphyromonas gingivalis in a mouse model. Clin Exp Immunol 2002; 128: 238-244. (Pubitemid 34534036)
19. Yusuf HR, Giles WH, Croft JB, Anda RF, Casper ML,. Impact of multiple risk factor profiles on determining cardiovascular disease risk. Prev Med 1998; 27: 1-9. (Pubitemid 28362981)
20. Hwang SJ, Ballantyne CM, Sharrett AR, et al., Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation 1997; 96: 4219-4225. (Pubitemid 28007447)
21. Malik I, Danesh J, Whincup P, et al., Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet 2001; 358: 971-976.
22. Collins RG, Velji R, Guevara NV, Hicks MJ, Chan L, Beaudet AL,. P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice. J Exp Med 2000; 191: 189-194. (Pubitemid 30043660)
23. Zakynthinos E, Pappa N,. Inflammatory biomarkers in coronary artery disease. J Cardiol 2009; 53: 317-333.
24. Nakajima T, Honda T, Domon H, et al., Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease. J Periodontal Res 2010; 45: 116-122.
25. Marcaccini AM, Meschiari CA, Sorgi CA, et al., Circulating interleukin-6 and high-sensitivity C-reactive protein decrease after periodontal therapy in otherwise healthy subjects. J Periodontol 2009; 80: 594-602.
26. Libby P, Ridker PM, Maseri A,. Inflammation and atherosclerosis. Circulation 2002; 105: 1135-1143. (Pubitemid 34212626)
27. Lindquist S, Craig EA,. The heat-shock proteins. Annu Rev Genet 1988; 22: 631-677. (Pubitemid 19156675)
28. Polla BS,. A role for heat shock proteins in inflammation? Immunol Today 1988; 9: 134-137. (Pubitemid 18097223)
29. Ando T, Kato T, Ishihara K, Ogiuchi H, Okuda K,. Heat shock proteins in the human periodontal disease process. Microbiol Immunol 1995; 39: 321-327.
30. Knoflach M, Kiechl S, Mayrl B, et al., T-cell reactivity against HSP60 relates to early but not advanced atherosclerosis. Atherosclerosis 2007; 195: 333-338. (Pubitemid 350103701)