Statistical analysis of rare sequence variants: An overview of collapsing methods

Genetic Epidemiology

Volumn 35, Issue SUPPL. 1, 2011, Pages

  Dering, Carmen ^a   Hemmelmann, Claudia ^a   Pugh, Elizabeth ^b   Ziegler, Andreas ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Association; Collapsing methods; Collection of rare variants; Common disease rare variant hypothesis; Contingency table; Generalized linear model; Next generation sequencing; Pooling methods

Indexed keywords

ALLELE; ARTICLE; BASE PAIRING; COCHRAN ARMITAGE TREND TEST; COLLAPSING AND SUMMATION TEST; EFFECT SIZE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; LOGISTIC REGRESSION ANALYSIS; MATHEMATICAL VARIABLE; MULTIVARIATE ANALYSIS; PERMUTATION; RANK SUM TEST; REGION OF INTEREST; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STANDARD; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VARIABLE THRESHOLD COLLAPSING METHOD; WEIGHTED SUM COLLAPSING APPROACH;

GENETIC PREDISPOSITION TO DISEASE; HUMANS; MODELS, GENETIC; MODELS, STATISTICAL; MOLECULAR EPIDEMIOLOGY; SEQUENCE ANALYSIS;

EID: 82455192533     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20643     Document Type: Article

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