Characterization of circulating and monocyte-derived dendritic cells in obese and diabetic patients

Molecular Immunology

Volumn 49, Issue 1-2, 2011, Pages 234-238

  Musilli, Claudia ^a   Paccosi, Sara ^a   Pala, Laura ^a   Gerlini, Gianni ^b   Ledda, Fabrizio ^a   Mugelli, Alessandro ^a   Rotella, Carlo Maria ^a   Parenti, Astrid ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b SANTA MARIA ANNUNZIATA HOSPITAL   (Italy)

Author keywords

Coronary smooth muscle cells; Dendritic cells; Obesity; Type 2 diabetes; Vascular wall remodeling

Indexed keywords

INSULIN;

ADULT; AGED; ARTICLE; CELL INTERACTION; CLINICAL ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DENDRITIC CELL; DIABETIC PATIENT; DONOR; FEMALE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; INSULIN RESISTANCE; MONOCYTE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PLASMACYTOID DENDRITIC CELL; PREMENOPAUSE; PRIORITY JOURNAL;

AGED; CELL ADHESION; CORONARY VESSELS; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 2; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INSULIN RESISTANCE; MONOCYTES; MUSCLE, SMOOTH, VASCULAR; OBESITY; STEM CELLS;

EID: 82455191628     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.08.019     Document Type: Article

References (24)

1. Andersson C.X., Gustafson B., Hammarstedt A., Hedjazifar S., Smith U. Inflamed adipose tissue, insulin resistance and vascular injury. Diabetes Metab. Res. Rev. 2008, 24:595-603.
2. Ausk H.J., Boyko E.J., Ioannou G.N. Insulin resistance predicts mortality in non-diabetic persons in the U.S. Diabetes Care 2010, 33:1179-1185.
3. Bellik L., Gerlini G., Parenti A., Ledda F., Pimpinelli N., Neri B., Pantalone D. Role of conventional treatments on circulating and monocyte-derived dendritic cells in colorectal cancer. Clin. Immunol. 2006, 121:74-80.
4. Bellik L., Musilli C., Vinci M.C., Ledda F., Parenti A. Human mature endothelial cells modulate peripheral blood mononuclear cells differentiation toward an endothelial phenotype. Exp. Cell Res. 2008, 314:2965-2974.
5. Blank S.E., Johnson E.C., Weeks D.K., Wysham C.H. Circulating dendritic cell number and intracellular TNF-alpha production in women with type 2 diabetes. Acta Diabetol. 2010, (Epub ahead of print).
6. Bobryshev Y.V., Lord R.S. Mapping of vascular dendritic cells in atherosclerotic arteries suggests their involvement in local immune-inflammatory reactions. Cardiovasc. Res. 1998, 37:799-810.
7. Chilton R., Wyatt J., Nandish S., Oliveros R., Lujan M. Cardiovascular comorbidities of type 2 diabetes mellitus: defining the potential of glucagon like peptide-1-based therapies. Am. J. Med. 2011, 124:S35-S53.
8. Corrales J.J., Almeida M., Burgo R.M., Hernández P., Miralles J.M., Orfao A. Decreased production of inflammatory cytokines by circulating monocytes and dendritic cells in type 2 diabetic men with atherosclerotic complications. J. Diabetes Complications 2007, 21:41-49.
9. Dzionek A., Fuchs A., Schmidt P., Cremer S., Zysk M., Miltenyi S., Buck D.W., Schmitz J. BDCA-2, BDCA-3, and BDCA-4. Three markers for distinct subsets of dendritic cells in human peripheral blood. J. Immunol. 2000, 165:6037-6046.
10. Friedman J.M., Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 1998, 395:763-770.
11. Ford E.S., Williamson D.F., Liu S. Weight change and diabetes incidence: findings from a national cohort of US adults. Am. J. Epidemiol. 1997, 146:214-222.
12. Grundy S.M., Pasternak R., Greenland P., Smith S., Fuster V. Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation 1999, 100:1481-1492.
13. Ishizaka N., Ishizaka Y., Takahashi E., Unuma T., Tooda E., Nagai R., Togo M., Tsukamoto K., Hashimoto H., Yamakado M. Association between insulin resistance and carotid arteriosclerosis in subjects with normal fasting glucose and normal glucose tolerance. Arterioscler. Thromb. Vasc. Biol. 2003, 23:295-301.
14. Libby P. Inflammation and cardiovascular disease mechanisms. Am. J. Clin. Nutr. 2006, 83:456S-460S.
15. Matsumoto S., Kishida K., Shimomura I., Maeda N., Nagaretani H., Matsuda M., Nishizawa H., Kihara S., Funahashi T., Matsuzawa Y., Yamada A., Yamashita S., Tamura S., Kawata S. Increased plasma HB-EGF associated with obesity and coronary artery disease. Biochem. Biophys. Res. Commun. 2002, 292:781-786.
16. Meng L., Park J., Cai Q., Lanting L., Reddy M.A., Natarajan R. Diabetic conditions promote binding of monocytes to vascular smooth muscle cells and their subsequent differentiation. Am. J. Physiol. Heart Circ. Physiol. 2010, 298:H736-H745.
17. Miltenyi S., Muller W., Weichel W., Radbruch A. High gradient magnetic cell separation with MACS. Cytometry 1990, 11:231-238.
18. Niessner A., Weyand C.M. Dendritic cells in atherosclerotic disease. Clin. Immunol. 2010, 134:925-932.
19. Reddy K.J., Singh M., Bangit J.R., Batsell R.R. The role of insulin resistance in the pathogenesis of atherosclerotic cardiovascular disease: an updated review. J. Cardiovasc. Med. (Hagerstown) 2010, 11:633-647.
20. Seifarth C.C., Hinkmann C., Hahn E.G., Lohmann T., Harsch I.A. Reduced frequency of peripheral dendritic cells in type 2 diabetes. Exp. Clin. Endocrinol. Diabetes 2008, 116:162-166.
21. Waltner-Romen M., Falkensammer G., Rabl W., Wick G. A previously unrecognized site of local accumulation of mononuclear cells. The vascular-associated lymphoid tissue. J. Histochem. Cytochem. 1998, 46:1347-1350.
22. Weis M., Schlichting C.L., Engleman E.G., Cooke J.P. Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases. Arterioscler. Thromb. Vasc. Biol. 2002, 22:1817-1823.
23. Yilmaz A., Lochno M., Traeg F., Cicha I., Reiss C., Stumpf C., Raaz D., Anger T., Amann K., Probst T., Ludwig J., Daniel W.G., Garlichs C.D. Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques. Atherosclerosis 2004, 176:101-110.
24. Yilmaz A., Weber J., Cicha I., Stumpf C., Klein M., Raithel D., Daniel W.G., Garlichs C.D. Decrease in circulating myeloid dendritic cell precursors in coronary artery disease. J. Am. Coll. Cardiol. 2006, 48:70-80.