Use of Bayesian networks to dissect the complexity of genetic disease: Application to the Genetic Analysis Workshop 17 simulated data

BMC Proceedings

Volumn 5, Issue SUPPL. 9, 2011, Pages

  Kang, Jia ^a,c   Zheng, Wei ^a,c   Li, Lun ^a,b,c   Lee, Joon Sang ^a,c   Yan, Xiting ^a,c   Zhao, Hongyu ^a,c  

^a YALE UNIVERSITY   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAYES THEOREM; CONFERENCE PAPER; GENETIC ANALYSIS; GENETIC DISORDER; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR;

EID: 82455183179     PISSN: None     EISSN: 17536561     Source Type: Journal    
DOI: 10.1186/1753-6561-5-S9-S37     Document Type: Conference Paper

References (9)

1. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Willer CJ, Speliotes EK, Loos RJF, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, et al. Nat Genet 2009 41 25 34 10.1038/ng.287 19079261
2. A data-adaptive sum test for disease association with multiple common or rare variants. Han FF, Pan W, Hum Hered 2010 70 42 54 10.1159/000288704 20413981
3. A Bayesian approach to causal discovery. Cooper G, Heckerman D, Meek C, Technical Report MSR-TR-97-05 Redmond, WA, Microsoft Research 1997
4. A theory of inferred causation. Pearl J, Verma TS, Principles of Knowledge Representation and Reasoning: Proceedings of the Second International Conference San Mateo, CA, Morgan Kaufmann, JA Allen, R Fikes, and E Sandewall, 1991 441 452
5. Causation, Prediction, and Search. Spirtes P, Glymour C, Scheines R, New York, Springer-Verlag 1993
6. Using Bayesian networks to analyze expression data. Friedman N, Linial M, Nachman I, Peer D, J Comput Biol 2000 7 601 620 10.1089/106652700750050961 11108481
7. An evaluation of statistical approaches to rare variant analysis in genetic association studies. Morris AP, Zeggini E, Genet Epidemiol 2010 34 188 193 10.1002/gepi.20450 19810025
8. A groupwise association test for rare mutations using a weighted sum statistic. Madsen BE, Browning SR, PLoS Genet 2009 5 1000384 10.1371/journal.pgen.1000384 19214210
9. Powerful SNP-set analysis for case-control genome-wide association studies. Wu MC, Kraft P, Epstein MP, Taylor DM, Chanock SJ, Hunter DJ, Lin X, Am J Hum Genet 2010 86 929 942 10.1016/j.ajhg.2010.05.002 20560208