Hepatocytes from wild-type or heterozygous donors are equally effective in achieving successful therapeutic liver repopulation in murine phenylketonuria (PKU)

Molecular Genetics and Metabolism

Volumn 104, Issue 3, 2011, Pages 235-240

  Hamman, Kelly J ^a   Winn, Shelley R ^a   Harding, Cary O ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Hepatocyte transplantation; Mouse model; Phenylalanine; Phenylalanine hydroxylase deficiency; Phenylketonuria; Therapeutic liver repopulation

Indexed keywords

PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE;

AMINO ACID BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; HEPATOCYTE TRANSPLANTATION; HETEROZYGOSITY; LIVER; LIVER CELL; MOUSE; NONHUMAN; PHENYLKETONURIA; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; DNA PRIMERS; GENE THERAPY; HEPATOCYTES; HYDROLASES; LIVER; LIVER REGENERATION; MICE; MICE, MUTANT STRAINS; MODELS, BIOLOGICAL; PHENOTYPE; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; PHENYLKETONURIAS; POLYMERASE CHAIN REACTION;

MURINAE; MUS;

EID: 82455179463     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2011.07.027     Document Type: Article

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