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Volumn 20, Issue 12, 2011, Pages 2023-2030

The power and the promise of liver cancer stem cell markers

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CELL MARKER; EPITHELIAL CELL ADHESION MOLECULE; HERMES ANTIGEN; HOE 33342; MICROSOMAL AMINOPEPTIDASE; MULTIDRUG RESISTANCE PROTEIN 1; THY 1 ANTIGEN; TUMOR MARKER;

EID: 82455168183     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0012     Document Type: Review
Times cited : (80)

References (81)
  • 1
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • Farazi PA and RA DePinho2006). Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6:674-687.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    Depinho, R.A.2
  • 4
    • 33646448921 scopus 로고    scopus 로고
    • Biology of normal and acute myeloid leukemia stem cells
    • Dick JE and T Lapidot2005). Biology of normal and acute myeloid leukemia stem cells. Int J Hematol 82:389-396.
    • (2005) Int. J. Hematol. , vol.82 , pp. 389-396
    • Dick, J.E.1    Lapidot, T.2
  • 5
    • 40749150740 scopus 로고    scopus 로고
    • + HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • + HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Oncogene 27:1749-1758.
    • (2008) Oncogene , vol.27 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3    Chan, K.W.4    Guan, X.Y.5
  • 7
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D and JE Dick1997). Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3:730-737.
    • (1997) Nat. Med. , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 8
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE and GJ Lindeman2008). Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8:755-768.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 11
    • 33847686753 scopus 로고    scopus 로고
    • CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity
    • Yin S, J Li, C Hu, X Chen, M Yao, M Yan, G Jiang, C Ge, H Xie, et al2007). CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int J Cancer 120:1444-1450.
    • (2007) Int. J. Cancer , vol.120 , pp. 1444-1450
    • Yin, S.1    Li, J.2    Hu, C.3    Chen, X.4    Yao, M.5    Yan, M.6    Jiang, G.7    Ge, C.8    Xie, H.9
  • 16
  • 17
    • 60449087921 scopus 로고    scopus 로고
    • EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/ progenitor cell features
    • Yamashita T, J Ji, A Budhu, M Forgues, W Yang, HY Wang, H Jia, Q Ye, LX Qin, et al2009). EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/ progenitor cell features. Gastroenterology 136:1012-1024.
    • (2009) Gastroenterology , vol.136 , pp. 1012-1024
    • Yamashita, T.1    Ji, J.2    Budhu, A.3    Forgues, M.4    Yang, W.5    Wang, H.Y.6    Jia, H.7    Ye, Q.8    Qin, L.X.9
  • 18
    • 49249122615 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells
    • Yang W, HX Yan, L Chen, Q Liu, YQ He, LX Yu, SH Zhang, DD Huang, L Tang, et al2008). Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells. Cancer Res 68:4287-4295.
    • (2008) Cancer Res. , vol.68 , pp. 4287-4295
    • Yang, W.1    Yan, H.X.2    Chen, L.3    Liu, Q.4    He, Y.Q.5    Yu, L.X.6    Zhang, S.H.7    Huang, D.D.8    Tang, L.9
  • 21
    • 33750302541 scopus 로고    scopus 로고
    • SP analysis may be used to identify cancer stem cell populations
    • Hadnagy A, L Gaboury, R Beaulieu and D Balicki2006). SP analysis may be used to identify cancer stem cell populations. Exp Cell Res 312:3701-3710.
    • (2006) Exp. Cell Res. , vol.312 , pp. 3701-3710
    • Hadnagy, A.1    Gaboury, L.2    Beaulieu, R.3    Balicki, D.4
  • 22
    • 33645514001 scopus 로고    scopus 로고
    • A side order of stem cells: The SP phenotype
    • Challen GA and MH Little2006). A side order of stem cells: the SP phenotype. Stem Cells 24:3-12.
    • (2006) Stem Cells , vol.24 , pp. 3-12
    • Challen, G.A.1    Little, M.H.2
  • 24
    • 53749088741 scopus 로고    scopus 로고
    • Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials
    • Shi GM, Y Xu, J Fan, J Zhou, XR Yang, SJ Qiu, Y Liao, WZ Wu, Y Ji, et al2008). Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials. J Cancer Res Clin Oncol 134:1155-1163.
    • (2008) J. Cancer Res. Clin. Oncol. , vol.134 , pp. 1155-1163
    • Shi, G.M.1    Xu, Y.2    Fan, J.3    Zhou, J.4    Yang, X.R.5    Qiu, S.J.6    Liao, Y.7    Wu, W.Z.8    Ji, Y.9
  • 26
    • 57349094741 scopus 로고    scopus 로고
    • Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling
    • Hu C, H Li, J Li, Z Zhu, S Yin, X Hao, M Yao, S Zheng and J Gu2008). Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling. Carcinogenesis 29:2289-2297.
    • (2008) Carcinogenesis , vol.29 , pp. 2289-2297
    • Hu, C.1    Li, H.2    Li, J.3    Zhu, Z.4    Yin, S.5    Hao, X.6    Yao, M.7    Zheng, S.8    Gu, J.9
  • 27
    • 34250903640 scopus 로고    scopus 로고
    • Histological and culture studies with respect to ABCG2 expression support the existence of a cancer cell hierarchy in human hepatocellular carcinoma
    • Zen Y, T Fujii, S Yoshikawa, H Takamura, T Tani, T Ohta and Y Nakanuma2007). Histological and culture studies with respect to ABCG2 expression support the existence of a cancer cell hierarchy in human hepatocellular carcinoma. Am J Pathol 170:1750-1762.
    • (2007) Am. J. Pathol. , vol.170 , pp. 1750-1762
    • Zen, Y.1    Fujii, T.2    Yoshikawa, S.3    Takamura, H.4    Tani, T.5    Ohta, T.6    Nakanuma, Y.7
  • 32
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien CA, A Pollett, S Gallinger and JE Dick2007). A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445:106-110.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 34
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collins AT, PA Berry, C Hyde, MJ Stower and NJ Maitland2005). Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65:10946-10951.
    • (2005) Cancer Res. , vol.65 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 35
    • 65449138684 scopus 로고    scopus 로고
    • + liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor TGF-beta-induced apoptosis
    • + liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-beta-induced apoptosis. Hepatology 49:1277-1286.
    • (2009) Hepatology , vol.49 , pp. 1277-1286
    • Ding, W.1    Mouzaki, M.2    You, H.3    Laird, J.C.4    Mato, J.5    Lu, S.C.6    Rountree, C.B.7
  • 38
    • 77951460399 scopus 로고    scopus 로고
    • Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta
    • You H, W Ding and CB Rountree2010). Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta. Hepatology 51:1635-1644.
    • (2010) Hepatology , vol.51 , pp. 1635-1644
    • You, H.1    Ding, W.2    Rountree, C.B.3
  • 39
    • 70350362332 scopus 로고    scopus 로고
    • Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells
    • Yao J, T Zhang, J Ren, M Yu and G Wu2009). Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells. Oncol Rep 22:781-787.
    • (2009) Oncol Rep , vol.22 , pp. 781-787
    • Yao, J.1    Zhang, T.2    Ren, J.3    Yu, M.4    Wu, G.5
  • 41
    • 73649128572 scopus 로고    scopus 로고
    • Clinicopathological analysis of CD133 and NCAM human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas
    • Tsuchiya A, H Kamimura, M Takamura, S Yamagiwa, Y Matsuda, Y Sato, M Nomoto, T Ichida and Y Aoyagi2009). Clinicopathological analysis of CD133 and NCAM human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas. Hepatol Res 39:1080-1090.
    • (2009) Hepatol. Res. , vol.39 , pp. 1080-1090
    • Tsuchiya, A.1    Kamimura, H.2    Takamura, M.3    Yamagiwa, S.4    Matsuda, Y.5    Sato, Y.6    Nomoto, M.7    Ichida, T.8    Aoyagi, Y.9
  • 44
    • 33745984808 scopus 로고    scopus 로고
    • Thy-1 as a regulator of cellcell and cell-matrix interactions in axon regeneration apoptosis adhesion migration cancer and fibrosis
    • Rege TA and JS Hagood2006). Thy-1 as a regulator of cellcell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB J 20:1045-1054.
    • (2006) FASEB J. , vol.20 , pp. 1045-1054
    • Rege, T.A.1    Hagood, J.S.2
  • 45
    • 33745601104 scopus 로고    scopus 로고
    • Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages
    • U S A
    • Dan YY, KJ Riehle, C Lazaro, N Teoh, J Haque, JS Campbell and N Fausto2006). Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proc Natl Acad Sci U S A 103:9912-9917.
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 9912-9917
    • Dan, Y.Y.1    Riehle, K.J.2    Lazaro, C.3    Teoh, N.4    Haque, J.5    Campbell, J.S.6    Fausto, N.7
  • 47
    • 67049156786 scopus 로고    scopus 로고
    • Tumor-promoting phenotype of CD90hi prostate cancer-associated fibroblasts
    • Zhao H and DM Peehl2009). Tumor-promoting phenotype of CD90hi prostate cancer-associated fibroblasts. Prostate 69:991-1000.
    • (2009) Prostate , vol.69 , pp. 991-1000
    • Zhao, H.1    Peehl, D.M.2
  • 54
    • 0033962047 scopus 로고    scopus 로고
    • Protein expression of CD44 standard and variant isoforms in hepatocellular carcinoma: Relationships with tumor grade clinicopathologic parameters p53 expression and patient survival
    • Endo K and T Terada2000). Protein expression of CD44 (standard and variant isoforms) in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, p53 expression, and patient survival. J Hepatol 32: 78-84.
    • (2000) J. Hepatol. , vol.32 , pp. 78-84
    • Endo, K.1    Terada, T.2
  • 55
    • 68349113773 scopus 로고    scopus 로고
    • Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: Drastic change of EpCAM expression during liver development
    • Tanaka M, M Okabe, K Suzuki, Y Kamiya, Y Tsukahara, S Saito and A Miyajima2009). Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development. Mech Dev 126:665-676.
    • (2009) Mech. Dev. , vol.126 , pp. 665-676
    • Tanaka, M.1    Okabe, M.2    Suzuki, K.3    Kamiya, Y.4    Tsukahara, Y.5    Saito, S.6    Miyajima, A.7
  • 57
    • 33749182067 scopus 로고    scopus 로고
    • The phenotypes of pluripotent human hepatic progenitors
    • Schmelzer E, E Wauthier and LM Reid2006). The phenotypes of pluripotent human hepatic progenitors. Stem Cells 24:1852-1858.
    • (2006) Stem Cells , vol.24 , pp. 1852-1858
    • Schmelzer, E.1    Wauthier, E.2    Reid, L.M.3
  • 58
    • 67651003100 scopus 로고    scopus 로고
    • The emerging role of epcam in cancer and stem cell signaling
    • Munz M, PA Baeuerle and O Gires2009). The Emerging Role of EpCAM in Cancer and Stem Cell Signaling. Cancer Res 69:5627-5629.
    • (2009) Cancer Res. , vol.69 , pp. 5627-5629
    • Munz, M.1    Baeuerle, P.A.2    Gires, O.3
  • 59
    • 75549088882 scopus 로고    scopus 로고
    • EpCAM a new marker for cancer stem cells in hepatocellular carcinoma
    • Terris B, C Cavard and C Perret2010). EpCAM, a new marker for cancer stem cells in hepatocellular carcinoma. J Hepatol 52:280-281.
    • (2010) J. Hepatol. , vol.52 , pp. 280-281
    • Terris, B.1    Cavard, C.2    Perret, C.3
  • 60
    • 36348991571 scopus 로고    scopus 로고
    • Activation of hepatic stem cell marker EpCAM by Wnt-betacatenin signaling in hepatocellular carcinoma
    • Yamashita T, A Budhu, M Forgues and XW Wang2007). Activation of hepatic stem cell marker EpCAM by Wnt-betacatenin signaling in hepatocellular carcinoma. Cancer Res 67:10831-10839.
    • (2007) Cancer Res. , vol.67 , pp. 10831-10839
    • Yamashita, T.1    Budhu, A.2    Forgues, M.3    Wang, X.W.4
  • 61
  • 63
    • 79953742352 scopus 로고    scopus 로고
    • CD13: Waving the flag for a novel cancer stem cell target
    • Christ B, P Stock and MM Dollinger2011). CD13: Waving the flag for a novel cancer stem cell target. Hepatology 53:1388-1390.
    • (2011) Hepatology , vol.53 , pp. 1388-1390
    • Christ, B.1    Stock, P.2    Dollinger, M.M.3
  • 64
    • 67349191354 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase as a marker for stem cells
    • Moreb JS2008). Aldehyde dehydrogenase as a marker for stem cells. Curr Stem Cell Res Ther 3:237-246.
    • (2008) Curr. Stem. Cell Res. Ther. , vol.3 , pp. 237-246
    • Moreb, J.S.1
  • 67
    • 0031408865 scopus 로고    scopus 로고
    • Antigenic phenotypes common to rat oval cells primary hepatocellular carcinomas and developing bile ducts
    • Hixson DC, L Chapman, A McBride, R Faris and L Yang1997). Antigenic phenotypes common to rat oval cells, primary hepatocellular carcinomas and developing bile ducts. Carcinogenesis 18:1169-1175.
    • (1997) Carcinogenesis , vol.18 , pp. 1169-1175
    • Hixson, D.C.1    Chapman, L.2    McBride, A.3    Faris, R.4    Yang, L.5
  • 68
    • 0027465440 scopus 로고
    • Keratin 14 protein in cultured nonparenchymal at hepatic epithelial cells: Characterization of keratin 14 and keratin 19 as antigens for the commonly used mouse monoclonal antibody OV-6
    • Bisgaard HC, DC Parmelee, HA Dunsford, S Sechi and SS Thorgeirsson1993). Keratin 14 protein in cultured nonparenchymal at hepatic epithelial cells: characterization of keratin 14 and keratin 19 as antigens for the commonly used mouse monoclonal antibody OV-6. Mol Carcinog 7:60-66.
    • (1993) Mol Carcinog , vol.7 , pp. 60-66
    • Bisgaard, H.C.1    Parmelee, D.C.2    Dunsford, H.A.3    Sechi, S.4    Thorgeirsson, S.S.5
  • 69
    • 0031654591 scopus 로고    scopus 로고
    • Immunolocalization of OV-6 a putative progenitor cell marker in human fetal and diseased pediatric liver
    • Crosby HA, SG Hubscher, RE Joplin, DA Kelly and AJ Strain1998). Immunolocalization of OV-6, a putative progenitor cell marker in human fetal and diseased pediatric liver. Hepatology 28:980-985.
    • (1998) Hepatology , vol.28 , pp. 980-985
    • Crosby, H.A.1    Hubscher, S.G.2    Joplin, R.E.3    Kelly, D.A.4    Strain, A.J.5
  • 72
    • 2542601615 scopus 로고    scopus 로고
    • Liver regeneration and repair: Hepatocytes progenitor cells and stem cells
    • Fausto N2004). Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology 39:1477-1487.
    • (2004) Hepatology , vol.39 , pp. 1477-1487
    • Fausto, N.1
  • 73
    • 33748554076 scopus 로고    scopus 로고
    • Hepatic progenitor cells stem cells and AFP expression in models of liver injury
    • Kuhlmann WD and P Peschke2006). Hepatic progenitor cells, stem cells, and AFP expression in models of liver injury. Int J Exp Pathol 87:343-359.
    • (2006) Int. J. Exp. Pathol. , vol.87 , pp. 343-359
    • Kuhlmann, W.D.1    Peschke, P.2
  • 75
    • 33745220772 scopus 로고    scopus 로고
    • Origin of hepatocellular carcinoma: Role of stem cells
    • Wu X-Z and D Chen2006). Origin of hepatocellular carcinoma: role of stem cells. J Gastroenterol Hepatol 21:1093-1098.
    • (2006) J. Gastroenterol. Hepatol. , vol.21 , pp. 1093-1098
    • Wu, X.-Z.1    Chen, D.2
  • 77
    • 70349783082 scopus 로고    scopus 로고
    • CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection
    • Yeh C-T, C-J Kuo, M-W Lai, T-C Chen, C-Y Lin, T-S Yeh and W-C Lee2009). CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection. BMC Cancer 9:324-324.
    • (2009) BMC Cancer , vol.9 , pp. 324-324
    • Yeh, C.-T.1    Kuo, C.-J.2    Lai, M.-W.3    Chen, T.-C.4    Lin, C.-Y.5    Yeh, T.-S.6    Lee, W.-C.7
  • 78
    • 47149111975 scopus 로고    scopus 로고
    • Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma
    • Song W, H Li, K Tao, R Li, Z Song, Q Zhao, F Zhang and K Dou2008). Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma. Int J Clin Pract 62:1212-1218.
    • (2008) Int. J. Clin. Pract. , vol.62 , pp. 1212-1218
    • Song, W.1    Li, H.2    Tao, K.3    Li, R.4    Song, Z.5    Zhao, Q.6    Zhang, F.7    Dou, K.8
  • 80
    • 77954019973 scopus 로고    scopus 로고
    • High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma
    • Yang XR, Y Xu, B Yu, J Zhou, SJ Qiu, GM Shi, BH Zhang, WZ Wu, YH Shi, et al2010). High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma. Gut 59:953-962.
    • (2010) Gut , vol.59 , pp. 953-962
    • Yang, X.R.1    Xu, Y.2    Yu, B.3    Zhou, J.4    Qiu, S.J.5    Shi, G.M.6    Zhang, B.H.7    Wu, W.Z.8    Shi, Y.H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.