Analysis of different medulloblastoma histotypes by two-dimensional gel and MALDI-TOF

Child's Nervous System

Volumn 27, Issue 12, 2011, Pages 2077-2085

  Zanini, Cristina ^a   Mandili, Giorgia ^b   Bertin, Daniele ^a   Cerutti, Francesco ^a   Baci, Denisa ^a   Leone, Marco ^c   Morra, Isabella ^c   Di Montezemolo Cordero, Luca ^a   Forni, Marco ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b Research Center for Experimental Medicine (CeRMS)   (Italy)

^c REGINA MARGHERITA CHILDREN S HOSPITAL   (Italy)

Author keywords

Histology; Medulloblastoma; Proteomics

Indexed keywords

TUMOR PROTEIN; VINCRISTINE;

AMINO ACID SEQUENCE; ARTICLE; CANCER CLASSIFICATION; CLINICAL ARTICLE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEDULLOBLASTOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN RESTRICTION; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS; UNINDEXED SEQUENCE; WESTERN BLOTTING;

ADOLESCENT; ADULT; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; CLUSTER ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HUMANS; INFANT; MALE; MEDULLOBLASTOMA; PEROXIREDOXINS; PROTEINS; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STATHMIN; YOUNG ADULT;

EID: 82455167859     PISSN: 02567040     EISSN: 14330350     Source Type: Journal    
DOI: 10.1007/s00381-011-1515-9     Document Type: Article

References (22)

1. Giangaspero F, Eberhart CG, Haapsalo H, Pietsch T, Wiestler O, Ellison DW (2007) Medulloblastoma. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) WHO classification of tumours of central nervous system. IARC Press, Lyon, pp 132-140
2. RJ Gilbertson A Gajjar 2005 Molecular biology of medulloblastoma: will it ever make a difference to clinical management? J Neurooncol 75 273 278 16195803 10.1007/s11060-005-6750-z 1:CAS:528:DC%2BD28XhtVynsLY%3D (Pubitemid 43019482)
3. S Rutkowski U Bode F Deinlein H Ottensmeier M Warmuth-Metz N Soerensen N Graf A Emser T Pietsch JE Wolff RD Kortmann J Kuehl, et al. 2005 Treatment of early childhood medulloblastoma by postoperative chemotherapy alone N Engl J Med 352 978 986 15758008 10.1056/NEJMoa042176 1:CAS:528:DC%2BD2MXit1WksLs%3D (Pubitemid 40349500)
4. A Gajjar M Chintagumpala D Ashley S Kellie LE Kun TE Merchant S Woo G Wheeler V Ahern MJ Krasin M Fouladi A Broniscer R Krance GA Hale CF Stewart R Dauser RA Sanford C Fuller C Lau JM Boyett D Wallace RJ Gilbertson, et al. 2006 Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial Lancet Oncol 7 813 820 17012043 10.1016/S1470-2045(06)70867-1 (Pubitemid 44464063)
5. M Kool J Koster J Bunt NE Hasselt A Lakeman P van Sluis D Troost NS Meeteren HN Caron J Cloos A Mrsić B Ylstra W Grajkowska W Hartmann T Pietsch D Ellison SC Clifford R Versteeg, et al. 2008 Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features PLoS One 3 e3088 18769486 10.1371/journal.pone.0003088
6. DW Ellison M Kocak J Dalton H Megahed ME Lusher SL Ryan W Zhao SL Nicholson RE Taylor S Bailey SC Clifford, et al. 2011 Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables J Clin Oncol 29 11 1400 1407 20921458 10.1200/JCO.2010.30.2810
7. S Rutkowski K von Hoff A Emser I Zwiener T Pietsch D Figarella-Branger F Giangaspero DW Ellison ML Garre V Biassoni RG Grundy JL Finlay G Dhall MA Raquin J Grill, et al. 2010 Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis J Clin Oncol 28 33 4961 4968 20940197 10.1200/JCO.2010.30.2299
8. G Barbero F Carta G Giribaldi G Mandili S Crobu C Ceruti D Fontana P Destefanis F Turrini, et al. 2006 Protein/RNA coextraction and small two-dimensional polyacrylamide gel electrophoresis for proteomic/gene expression analysis of renal cancer biopsies Anal Biochem 349 62 71 16307718 10.1016/j.ab.2005.10.020 1:CAS:528:DC%2BD28XotVGltg%3D%3D (Pubitemid 43129558)
9. Development Core Team (2009) R: a Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. http://www.R-project.org
10. Bolker B, Bonebakker L, Gentleman R, Huber W, Liaw A, Lumley. T, Maechler M, Magnusson A, Moeller S, Schwartz M, Venables B (2010) gplots: Various R programming tools for plotting data. R package version 2.8.0. http://CRAN.R-project.org/package=gplots
11. AS Polans D Witkowska TL Haley D Amundson L Baizer G Adamus, et al. 1995 Recoverin, a photoreceptor-specific calcium-binding protein, is expressed by the tumor of a patient with cancer-associated retinopathy Proc Natl Acad Sci U S A. 96 9176 9180 10.1073/pnas.92.20.9176
12. RF Deighton R McGregor J Kemp J McCulloch IR Whittle, et al. 2010 Glioma pathophysiology: insights emerging from proteomics Brain Pathol 20 691 701 20175778 10.1111/j.1750-3639.2010.00376.x 1:CAS:528:DC%2BC3cXpsVyhtbg%3D
13. M Le Mercier S Fortin V Mathieu R Kiss F Lefranc, et al. 2010 Galectins and gliomas Brain Pathol 20 17 27 19371355 10.1111/j.1750-3639.2009.00270.x
14. NL Miller R Wevrick PL Mellon 2009 Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development Hum Mol Genet 18 248 260 18930956 10.1093/hmg/ddn344 1:CAS:528:DC%2BD1cXhsFagtLfE
15. MF Kuo HS Wang QT Kuo CT Shun HC Hsu SH Yang RH Yuan, et al. 2009 High expression of stathmin protein predicts a fulminant course in medulloblastoma J. Neurosurg Pediatr 4 74 80 19569914 10.3171/2009.2.PEDS08287
16. Zanini C, Mandili G, Baci D, Morra I, Forni M (2010) Proteomic profile modification of anaplastic medulloblastoma after in-vivo radiotherapy: a case study. Journal Cancer Therapy 2:97-103. doi: 10.4236/jct.2010.12017 http://www.scirp.org/journal/jct
17. Zhang DY, Ye F, Gao L, Liu X, Zhao X et al (2009) Proteomics, pathway array and signaling network-based medicine in cancer. Cell Div. 4:20
18. A Peyrl K Krapfenbauer I Slavc JW Yang T Strobel G Lubec, et al. 2003 Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and principles Proteomics 3 1781 1800 12973738 10.1002/pmic.200300460 1:CAS:528:DC%2BD3sXnsFKks70%3D (Pubitemid 37129825)
19. C Zanini G Mandili F Pulerà I Morra P Peretta F Turrini M Forni, et al. 2009 Immunohistochemical and proteomic profile of melanotic medulloblastoma Pediatr Blood Cancer 52 875 877 19061219 10.1002/pbc.21887
20. K Hoff W Hartmann AO von Bueren NU Gerber MA Grotzer T Pietsch S Rutkowski, et al. 2010 Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors Pediatr Blood Cancer 54 369 376 10.1002/pbc.22339
21. T Hidvegi M Ewing P Hale C Dippold C Beckett C Kemp N Maurice A Mukherjee C Goldbach S Watkins G Michalopoulos DH Perlmutter, et al. 2010 An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis Science 329 229 232 20522742 10.1126/science.1190354 1:CAS:528:DC%2BC3cXosVWgu70%3D
22. BS Mitchell 2003 The proteasome-an emerging therapeutic target in cancer N Engl J Med 348 2597 2598 12826633 10.1056/NEJMp030092 (Pubitemid 36741586)