Studies on the metabolism and disposition of the new retinoid 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]benzoi c acid. 4th Communication: Absorption, metabolism, excretion and plasma protein binding in various animals and man

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 3, 1997, Pages 259-269

  Mizojiri, Kenji ^a   Okabe, Hiroshi ^a   Sugeno, Koichi ^a   Misaki, Atsushi ^a   Ito, Masashi ^a   Kominami, Goro ^a   Esumi, Yoshio ^b   Takaichi, Matsuo ^b   Harada, Tomoko ^b   Seki, Hideaki ^b   Inaba, Atsuhiro ^b  

^a SHIONOGI AND CO LTD   (Japan)

^b DAIICHI PURE CHEMICALS CO LTD   (Japan)

Author keywords

Am 80, absorption, excretion, metabolism, subcutaneous administration, topical application; antipsoriatics, topical; CAS 94497 51 5; retinobenzoic acid

Indexed keywords

CARBON 14; DRUG METABOLITE; RETINOID; TAMIBAROTENE;

ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG FECES LEVEL; DRUG PROTEIN BINDING; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; MOUSE; RABBIT; RADIOIMMUNOASSAY; SUBCUTANEOUS DRUG ADMINISTRATION; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; BENZOATES; BIOTRANSFORMATION; BLOOD PROTEINS; DOGS; FEMALE; HUMANS; INJECTIONS, SUBCUTANEOUS; INTESTINAL ABSORPTION; MALE; MICE; MICE, INBRED ICR; OINTMENTS; PROTEIN BINDING; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RETINOIDS; SUSPENSIONS; TETRAHYDRONAPHTHALENES;

EID: 8244256655     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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