메뉴 건너뛰기




Volumn 28, Issue 11, 2011, Pages 973-985

Survival benefit of eribulin mesylate in heavily pretreated metastatic breast cancer: What next?

Author keywords

anthracyclines; capecitabine; clinical trials; eribulin mesylate; metastatic breast cancer; microtubules; taxanes

Indexed keywords

ANTHRACYCLINE; CAPECITABINE; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERIBULIN; GAMMA UROGASTRONE; GRANULOCYTE COLONY STIMULATING FACTOR; HALICHONDRIN B; IXABEPILONE; NANOPARTICLE; NAVELBINE; PACLITAXEL; TAXANE DERIVATIVE; TRASTUZUMAB;

EID: 82355191648     PISSN: 0741238X     EISSN: 18658652     Source Type: Journal    
DOI: 10.1007/s12325-011-0070-9     Document Type: Review
Times cited : (9)

References (56)
  • 1
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • 21685461 10.3322/caac.20121
    • R. Siegel E. Ward O. Brawley A. Jemal 2011 Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths CA Cancer J Clin. 61 212 236 21685461 10.3322/caac.20121
    • (2011) CA Cancer J Clin. , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 2
    • 33847638137 scopus 로고    scopus 로고
    • Estimates of the cancer incidence and mortality in Europe in 2006
    • DOI 10.1093/annonc/mdl498
    • J. Ferlay P. Autier M. Boniol, et al. 2007 Estimates of the cancer incidence and mortality in Europe in 2006 Ann Oncol. 18 581 592 17287242 10.1093/annonc/mdl498 1:STN:280:DC%2BD2s7hslSgtw%3D%3D (Pubitemid 46359643)
    • (2007) Annals of Oncology , vol.18 , Issue.3 , pp. 581-592
    • Ferlay, J.1    Autier, P.2    Boniol, M.3    Heanue, M.4    Colombet, M.5    Boyle, P.6
  • 3
    • 21344463119 scopus 로고    scopus 로고
    • New developments in the treatment of metastatic breast cancer: From chemotherapy to biological therapy
    • G. Mariani 2005 New developments in the treatment of metastatic breast cancer: from chemotherapy to biological therapy Ann Oncol. 16 Suppl.2 191 194
    • (2005) Ann Oncol. , vol.16 , Issue.SUPPL. 2 , pp. 191-194
    • Mariani, G.1
  • 5
    • 77949561690 scopus 로고    scopus 로고
    • Last accessed July 1, 2011
    • Breast cancer facts and figures 2009-2010. Available at: http://www.cancer.org/Research/CancerFactsFigures/BreastCancerFactsFigures/ breastcancer-facts-figures-2009-2010. Last accessed July 1, 2011.
    • Breast Cancer Facts and Figures 2009-2010
  • 6
    • 9144268610 scopus 로고    scopus 로고
    • Facts and controversies in systemic treatment of metastatic breast cancer
    • DOI 10.1634/theoncologist.9-6-617
    • C. Bernard-Marty F. Cardoso M.J. Piccart 2004 Facts and controversies in systemic treatment of metastatic breast cancer Oncologist. 9 617 632 15561806 10.1634/theoncologist.9-6-617 (Pubitemid 39546403)
    • (2004) Oncologist , vol.9 , Issue.6 , pp. 617-632
    • Bernard-Marty, C.1    Cardoso, F.2    Piccart, M.J.3
  • 7
    • 46949103546 scopus 로고    scopus 로고
    • Metastatic breast cancer: The treatment challenge
    • DOI 10.3816/CBC.2008.n.025
    • S.E. Jones 2008 Metastatic breast cancer: the treatment challenge Clin Breast Cancer. 8 224 233 18650152 10.3816/CBC.2008.n.025 1:CAS:528: DC%2BD1cXovFCiu7s%3D (Pubitemid 351962143)
    • (2008) Clinical Breast Cancer , vol.8 , Issue.3 , pp. 224-233
    • Jones, S.E.1
  • 8
    • 70049100788 scopus 로고    scopus 로고
    • ESO-MBC Task Force. International guidelines for management of metastatic breast cancer: Combination vs sequential single-agent chemotherapy
    • 19657108 10.1093/jnci/djp235 1:CAS:528:DC%2BD1MXhtFWhu73J
    • F. Cardoso P.L. Bedard E.P. Winer, et al. 2009 ESO-MBC Task Force. International guidelines for management of metastatic breast cancer: combination vs sequential single-agent chemotherapy J Natl Cancer Inst. 101 1174 1781 19657108 10.1093/jnci/djp235 1:CAS:528:DC%2BD1MXhtFWhu73J
    • (2009) J Natl Cancer Inst. , vol.101 , pp. 1174-1781
    • Cardoso, F.1    Bedard, P.L.2    Winer, E.P.3
  • 9
    • 50549096593 scopus 로고    scopus 로고
    • Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
    • 18711184 10.1200/JCO.2007.11.9362
    • K.S. Albain S.M. Nag G. Calderillo-Ruiz, et al. 2008 Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment J Clin Oncol. 26 3950 3957 18711184 10.1200/JCO.2007.11.9362
    • (2008) J Clin Oncol. , vol.26 , pp. 3950-3957
    • Albain, K.S.1    Nag, S.M.2    Calderillo-Ruiz, G.3
  • 11
    • 70349260426 scopus 로고    scopus 로고
    • Single agent versus combination chemotherapy for metastatic breast cancer
    • CD003372
    • Carrick S, Parker S, Thornton CE, et al. Single agent versus combination chemotherapy for metastatic breast cancer. Cochrane Database Syst Rev. 2009;(2):CD003372.
    • (2009) Cochrane Database Syst Rev. , Issue.2
    • Carrick, S.1    Parker, S.2    Thornton, C.E.3
  • 12
    • 37549072095 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network Last accessed July 1, 2011
    • National Comprehensive Cancer Network. 2011 NCCN Clinical Practice Guidelines in Oncology: Breast Cancer. Available at: http://www.nccn.org/ professionals/physician-gls/PDF/breast.pdf. Last accessed July 1, 2011.
    • 2011 NCCN Clinical Practice Guidelines in Oncology: Breast Cancer
  • 13
    • 32944482677 scopus 로고    scopus 로고
    • Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
    • DOI 10.1200/JCO.2005.04.937
    • W.J. Gradishar S. Tjulandin N. Davidson, et al. 2005 Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer J Clin Oncol. 23 7794 7803 16172456 10.1200/JCO.2005.04.937 1:CAS:528:DC%2BD2MXht1Cqs7nK (Pubitemid 46657376)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.31 , pp. 7794-7803
    • Gradishar, W.J.1    Tjulandin, S.2    Davidson, N.3    Shaw, H.4    Desai, N.5    Bhar, P.6    Hawkins, M.7    O'Shaughnessy, J.8
  • 14
    • 53149127645 scopus 로고    scopus 로고
    • Preclinical discovery of ixabepilone, a highly active antineoplastic agent
    • 18347795 10.1007/s00280-008-0724-8 1:CAS:528:DC%2BD1cXhtF2kur%2FM
    • F.Y. Lee R. Borzilleri C.R. Fairchild, et al. 2008 Preclinical discovery of ixabepilone, a highly active antineoplastic agent Cancer Chemother Pharmacol. 63 157 166 18347795 10.1007/s00280-008-0724-8 1:CAS:528:DC%2BD1cXhtF2kur%2FM
    • (2008) Cancer Chemother Pharmacol. , vol.63 , pp. 157-166
    • Lee, F.Y.1    Borzilleri, R.2    Fairchild, C.R.3
  • 15
    • 57149135866 scopus 로고    scopus 로고
    • Preclinical efficacy spectrum and pharmacokinetics of ixabepilone
    • 18350296 10.1007/s00280-008-0727-5 1:CAS:528:DC%2BD1cXhsVelurjJ
    • F.Y. Lee R. Smykla K. Johnston, et al. 2009 Preclinical efficacy spectrum and pharmacokinetics of ixabepilone Cancer Chemother Pharmacol. 63 201 212 18350296 10.1007/s00280-008-0727-5 1:CAS:528:DC%2BD1cXhsVelurjJ
    • (2009) Cancer Chemother Pharmacol. , vol.63 , pp. 201-212
    • Lee, F.Y.1    Smykla, R.2    Johnston, K.3
  • 17
    • 67049161336 scopus 로고    scopus 로고
    • Analysis of overall survival among patients (pts) with metastatic breast cancer (MBC) receiving either ixabepilone plus capecitabine or capecitabine alone: Results from two randomized phase III trials
    • 5-7 Sep 2008, (Abstr 186). Washington, DC
    • Hortobagyi G, Perez E, Vrdoljak E, et al. Analysis of overall survival among patients (pts) with metastatic breast cancer (MBC) receiving either ixabepilone plus capecitabine or capecitabine alone: results from two randomized phase III trials. In Proceedings of the American Society of Clinical Oncology (ASCO) Breast Cancer Symposium, 5-7 Sep 2008, (Abstr 186). Washington, DC.
    • Proceedings of the American Society of Clinical Oncology (ASCO) Breast Cancer Symposium
    • Hortobagyi, G.1    Perez, E.2    Vrdoljak, E.3
  • 18
    • 0022378694 scopus 로고
    • Norhalichondrin A: An antitumor polyether macrolide from a marine sponge
    • DOI 10.1021/ja00302a042
    • D. Uemura K. Takahashi T. Yamamoto, et al. 1985 An antitumor polyether macrolide from a marine sponge J Am Chem Soc. 107 4796 4798 10.1021/ja00302a042 1:CAS:528:DyaL2MXksFWntL8%3D (Pubitemid 16244006)
    • (1985) Journal of the American Chemical Society , vol.107 , Issue.16 , pp. 4796-4798
    • Uemura, D.1    Takahashi, K.2    Yamamoto, T.3
  • 19
    • 0022709534 scopus 로고
    • Halichondrins: Antitumor polyether macrolides from a marine sponge
    • Y. Hirata D. Uemura 1986 Halichondrins: antitumor polyether macrolides from a marine sponge Pure Appl Chem. 58 701 710 10.1351/pac198658050701 1:CAS:528:DyaL28XlvVOqsLs%3D (Pubitemid 16557441)
    • (1986) Pure and Applied Chemistry , vol.58 , Issue.5 , pp. 701-710
    • Hirata Yoshimasa1    Uemura Daisuke2
  • 21
    • 4143052665 scopus 로고    scopus 로고
    • Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389
    • DOI 10.1158/0008-5472.CAN-04-1169
    • G. Kuznetsov M.J. Towle H. Cheng, et al. 2004 Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389 Cancer Res. 64 5760 5766 15313917 10.1158/0008-5472.CAN-04-1169 1:CAS:528:DC%2BD2cXmslaksrw%3D (Pubitemid 39095575)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5760-5766
    • Kuznetsov, G.1    Towle, M.J.2    Cheng, H.3    Kawamura, T.4    TenDyke, K.5    Liu, D.6    Kishi, Y.7    Yu, M.J.8    Littlefield, B.A.9
  • 22
    • 0027518597 scopus 로고
    • Interaction of halichondrin B and homohalichondrin B with bovine brain tubulin
    • DOI 10.1016/0006-2952(93)90079-C
    • R.F. Luduena M.C. Roach V. Prasad G.R. Pettit 1993 Interaction of halichondrin B and homohalichondrin B with bovine brain tubulin Biochem Pharmacol. 45 421 427 8435093 10.1016/0006-2952(93)90079-C 1:CAS:528: DyaK3sXit1ymsbc%3D (Pubitemid 23042642)
    • (1993) Biochemical Pharmacology , vol.45 , Issue.2 , pp. 421-427
    • Luduena, R.F.1    Roach, M.C.2    Prasad, V.3    Pettit, G.R.4
  • 23
    • 23144433687 scopus 로고    scopus 로고
    • The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth
    • DOI 10.1158/1535-7163.MCT-04-0345
    • M.A. Jordan K. Kamath T. Manna, et al. 2005 The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth Mol Cancer Ther. 4 1086 1095 16020666 10.1158/1535-7163.MCT- 04-0345 1:CAS:528:DC%2BD2MXmtFSltrY%3D (Pubitemid 41079102)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.7 , pp. 1086-1095
    • Jordan, M.A.1    Kamath, K.2    Manna, T.3    Okouneva, T.4    Miller, H.P.5    Davis, C.6    Littlefield, B.A.7    Wilson, L.8
  • 25
    • 67449147109 scopus 로고    scopus 로고
    • A phase i study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies
    • 19509177 10.1158/1078-0432.CCR-08-2429 1:CAS:528:DC%2BD1MXntlOisbY%3D
    • S. Goel A.C. Mita M. Mita, et al. 2009 A phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies Clin Cancer Res. 15 4207 4212 19509177 10.1158/1078-0432.CCR-08-2429 1:CAS:528:DC%2BD1MXntlOisbY%3D
    • (2009) Clin Cancer Res. , vol.15 , pp. 4207-4212
    • Goel, S.1    Mita, A.C.2    Mita, M.3
  • 26
    • 67449123315 scopus 로고    scopus 로고
    • Phase i study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors
    • 19509146 10.1158/1078-0432.CCR-09-0360 1:CAS:528:DC%2BD1MXntlOisbc%3D
    • A.R. Tan E.H. Rubin D.C. Walton, et al. 2009 Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors Clin Cancer Res. 15 4213 4219 19509146 10.1158/1078-0432.CCR-09-0360 1:CAS:528:DC%2BD1MXntlOisbc%3D
    • (2009) Clin Cancer Res. , vol.15 , pp. 4213-4219
    • Tan, A.R.1    Rubin, E.H.2    Walton, D.C.3
  • 27
    • 67649908927 scopus 로고    scopus 로고
    • Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
    • 19349550 10.1200/JCO.2008.17.7618 1:CAS:528:DC%2BD1MXoslyis74%3D
    • L.T. Vahdat B. Pruitt C.J. Fabian, et al. 2009 Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane J Clin Oncol. 27 2954 2961 19349550 10.1200/JCO.2008.17.7618 1:CAS:528:DC%2BD1MXoslyis74%3D
    • (2009) J Clin Oncol. , vol.27 , pp. 2954-2961
    • Vahdat, L.T.1    Pruitt, B.2    Fabian, C.J.3
  • 28
    • 77957594393 scopus 로고    scopus 로고
    • Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine
    • 20679609 10.1200/JCO.2009.25.8467 1:CAS:528:DC%2BC3cXht1eqsbzM
    • J. Cortes L. Vahdat J.L. Blum, et al. 2010 Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine J Clin Oncol. 28 3922 3928 20679609 10.1200/JCO.2009.25.8467 1:CAS:528:DC%2BC3cXht1eqsbzM
    • (2010) J Clin Oncol. , vol.28 , pp. 3922-3928
    • Cortes, J.1    Vahdat, L.2    Blum, J.L.3
  • 29
    • 79952487463 scopus 로고    scopus 로고
    • EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) investigators. Eribulinmonotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): A phase 3 open-label randomised study
    • 21376385 10.1016/S0140-6736(11)60070-6 1:CAS:528:DC%2BC3MXjtFWgs7c%3D
    • J. Cortes J. O'shaughnessy D. Loesch, et al. 2011 EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) investigators. Eribulinmonotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study Lancet 377 914 923 21376385 10.1016/S0140-6736(11)60070-6 1:CAS:528:DC%2BC3MXjtFWgs7c%3D
    • (2011) Lancet , vol.377 , pp. 914-923
    • Cortes, J.1    O'Shaughnessy, J.2    Loesch, D.3
  • 32
    • 84859785785 scopus 로고    scopus 로고
    • Northwestern University ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]
    • Northwestern University. Carboplatin and eribulin mesylate in triple negative breast cancer patients. In: ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]. Available at: http://clinicaltrials.gov/show/NCT01372579 NLM identifier: NCT01372579.
    • Carboplatin and Eribulin Mesylate in Triple Negative Breast Cancer Patients
  • 34
    • 84859746443 scopus 로고    scopus 로고
    • ACORN Research LLC ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]
    • ACORN Research LLC. Study of neoadjuvantcarboplatin, eribulin and trastuzumab for operable HER2 positive breast cancer. In: ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]. Available at: http://clinicaltrials.gov/show/NCT01388647 NLM identifier: NCT01388647.
    • Study of Neoadjuvantcarboplatin, Eribulin and Trastuzumab for Operable HER2 Positive Breast Cancer
  • 36
    • 84859772091 scopus 로고    scopus 로고
    • California Cancer Consortium ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]
    • California Cancer Consortium. E7389 and Cisplatin in treating patients with advanced solid tumors. In: ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]. Available at: http://clinicaltrials.gov/show/NCT00415324 NLM identifier: NCT00415324.
    • E7389 and Cisplatin in Treating Patients with Advanced Solid Tumors
  • 39
    • 84859750191 scopus 로고    scopus 로고
    • Eisai Inc. ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]
    • Eisai Inc. A dose-finding study of E7389 in combination with carboplatin in patients with solid tumors. In: ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]. Available at: http://clinicaltrials.gov/show/NCT00268905 NLM identifier: NCT00268905.
    • A Dose-finding Study of E7389 in Combination with Carboplatin in Patients with Solid Tumors
  • 42
    • 77952696144 scopus 로고    scopus 로고
    • Phase i study of E7389/gemcitabine combination in patients with advanced solid tumors
    • Abstract e13509
    • Goel R, Chen E, Welch S, et al. Phase I study of E7389/gemcitabine combination in patients with advanced solid tumors. J Clin Oncol. 2009;27(Suppl.). Abstract e13509.
    • (2009) J Clin Oncol. , vol.27 , Issue.SUPPL.
    • Goel, R.1    Chen, E.2    Welch, S.3
  • 43
    • 79551561542 scopus 로고    scopus 로고
    • Phase IB study of eribulin mesylate in combination with carboplatin in patients with advanced solid tumors
    • U. Swami D.P. Petrylak H. Raftopoulos, et al. 2010 Phase IB study of eribulin mesylate in combination with carboplatin in patients with advanced solid tumors J Clin Oncol Meeting Abstracts. 28 Suppl. 15
    • (2010) J Clin Oncol Meeting Abstracts. , vol.28 , Issue.SUPPL. , pp. 15
    • Swami, U.1    Petrylak, D.P.2    Raftopoulos, H.3
  • 45
    • 4243891934 scopus 로고    scopus 로고
    • Sanofi-Aventis ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]
    • Sanofi-Aventis. Combination chemotherapy with or without trastuzumab in treating women with breast cancer. In: ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2000-[cited 2011 Oct 4]. Available at: http://clinicaltrials.gov/show/NCT00021255 NLM identifier: NCT00021255.
    • Combination Chemotherapy with or Without Trastuzumab in Treating Women with Breast Cancer
  • 46
    • 82355184963 scopus 로고    scopus 로고
    • The relationship between age and survival outcomes for eribulin in metastatic breast cancer
    • Abstract 1060
    • Twelves C, Vahdat LT, Cortes J, et al. The relationship between age and survival outcomes for eribulin in metastatic breast cancer. J Clin Oncol. 2011;29(Suppl.). Abstract 1060.
    • (2011) J Clin Oncol. , vol.29 , Issue.SUPPL.
    • Twelves, C.1    Vahdat, L.T.2    Cortes, J.3
  • 47
    • 33745000162 scopus 로고    scopus 로고
    • A Phase i pharmacokinetic and target validation study of the novel anti-tubulin agent E7389: A California Cancer Consortium trial
    • T.W. Synold R.J. Morgan E.M. Newman, et al. 2005 A Phase I pharmacokinetic and target validation study of the novel anti-tubulin agent E7389: A California Cancer Consortium trial J Clin Oncol 23 16S 3036
    • (2005) J Clin Oncol , vol.23 , Issue.16 S , pp. 3036
    • Synold, T.W.1    Morgan, R.J.2    Newman, E.M.3
  • 48
    • 84867841684 scopus 로고    scopus 로고
    • Eribulin mesylate in patients with refractory cancers: A Phase i study
    • Sep 2. [Epub ahead of print]
    • Mukohara T, Nagai S, Mukai H, Namiki M, Minami H. Eribulin mesylate in patients with refractory cancers: a Phase I study. Invest New Drugs. 2011 Sep 2. [Epub ahead of print]
    • (2011) Invest New Drugs.
    • Mukohara, T.1    Nagai, S.2    Mukai, H.3    Namiki, M.4    Minami, H.5
  • 49
    • 82355162633 scopus 로고    scopus 로고
    • Population pharmacokinetic-pharmacodynamic (PK/PD) analysis of safety and efficacy of eribulin in metastatic or loclly advanced breast cancer patients
    • A. Gupta D.R. Mould L. Reyderman, et al. 2010 Population pharmacokinetic-pharmacodynamic (PK/PD) analysis of safety and efficacy of eribulin in metastatic or loclly advanced breast cancer patients Ann Oncol. 21 Suppl.8 viii96 viii121
    • (2010) Ann Oncol. , vol.21 , Issue.SUPPL.8
    • Gupta, A.1    Mould, D.R.2    Reyderman, L.3
  • 50
    • 79551559614 scopus 로고    scopus 로고
    • Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole (KET)
    • Berlin, Germany, November 16-19 Abstract 574
    • Devriese L, Wanders J, Jenner A, et al. Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole (KET). 22nd EORTC-AACR-NCI meeting, Berlin, Germany, November 16-19, 2010. Abstract 574.
    • (2010) 22nd EORTC-AACR-NCI Meeting
    • Devriese, L.1    Wanders, J.2    Jenner, A.3
  • 51
    • 79551555821 scopus 로고    scopus 로고
    • Eribulin mesylate pharmacokinetics in patients with hepatic impairment
    • P. Witteveen S. Marchetti M. Mergui-Roelvink, et al. 2010 Eribulin mesylate pharmacokinetics in patients with hepatic impairment J Clin Oncol. 28 Suppl. 15s
    • (2010) J Clin Oncol. , vol.28 , Issue.SUPPL.
    • Witteveen, P.1    Marchetti, S.2    Mergui-Roelvink, M.3
  • 52
    • 82355167182 scopus 로고    scopus 로고
    • Eribulin dosing in patients with advanced solid tumors and hepatic impairment
    • Abstr 2544
    • Devriese LA, Witteveen P, Voest EE, et al. Eribulin dosing in patients with advanced solid tumors and hepatic impairment. J Clin Oncol. 2011;29(Suppl.):Abstr 2544.
    • (2011) J Clin Oncol. , vol.29 , Issue.SUPPL.
    • Devriese, L.A.1    Witteveen, P.2    Voest, E.E.3
  • 53
    • 79551553908 scopus 로고    scopus 로고
    • Efficacy and safety of eribulin in Japanese patients (pts) with advanced breast cancer
    • H. Iwata K. Aogi N. Masuda, et al. 2010 Efficacy and safety of eribulin in Japanese patients (pts) with advanced breast cancer J Clin Oncol. 28 Suppl. 15s
    • (2010) J Clin Oncol. , vol.28 , Issue.SUPPL.
    • Iwata, H.1    Aogi, K.2    Masuda, N.3
  • 54
    • 30344437279 scopus 로고    scopus 로고
    • Class III β-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel
    • DOI 10.1158/1535-7163.MCT-05-0244
    • P. Seve J. Mackey S. Isaac, et al. 2005 Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel Mol Cancer Ther. 4 2001 2007 16373715 10.1158/1535-7163.MCT-05-0244 1:CAS:528:DC%2BD2MXhtlCnsrjI (Pubitemid 43056983)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.12 , pp. 2001-2007
    • Seve, P.1    Mackey, J.2    Isaac, S.3    Tredan, O.4    Souquet, P.-J.5    Perol, M.6    Lai, R.7    Voloch, A.8    Dumontet, C.9
  • 56
    • 34250705854 scopus 로고    scopus 로고
    • Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer
    • DOI 10.1158/1535-7163.MCT-06-0592
    • A. Jimeno G. Hallur A. Chan, et al. 2007 Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer Mol Cancer Ther. 6 1509 1516 17483439 10.1158/1535-7163.MCT-06-0592 1:CAS:528: DC%2BD2sXotFaltL4%3D (Pubitemid 46954017)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.5 , pp. 1509-1516
    • Jimeno, A.1    Hallur, G.2    Chan, A.3    Zhang, X.4    Cusatis, G.5    Chan, F.6    Shah, P.7    Chen, R.8    Hamel, E.9    Garrett-Mayer, E.10    Khan, S.11    Hidalgo, M.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.