Mutations in VP2 and VP1 capsid proteins increase infectivity and mouse lethality of enterovirus 71 by virus binding and RNA accumulation enhancement

Virology

Volumn 422, Issue 1, 2012, Pages 132-143

  Huang, Sheng Wen ^a   Wang, Ya Fang ^a   Yu, Chun Keung ^a   Su, Ih Jen ^b   Wang, Jen Ren ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Capsid protein; Enterovirus 71; Infectivity

Indexed keywords

CAPSID PROTEIN; GLUTAMIC ACID; GLUTAMINE; LYSINE; METHIONINE; PROTEIN VP1; PROTEIN VP2;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CYTOTOXICITY; ENTEROVIRUS; HUMAN; HUMAN CELL; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIROGENESIS; VIRUS INFECTION; VIRUS MUTATION; VIRUS REPLICATION; VIRUS TITRATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; APOPTOSIS; CAPSID PROTEINS; CERCOPITHECUS AETHIOPS; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; GENETIC VARIATION; HAND, FOOT AND MOUTH DISEASE; MICE; MUTANT PROTEINS; MUTATION; RNA, VIRAL; VERO CELLS; VIRULENCE FACTORS; VIRUS ATTACHMENT;

HUMAN ENTEROVIRUS 71; MIRIDAE; MUS; POLIOVIRUS;

EID: 82355190097     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.10.015     Document Type: Article

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