Environmental risk assessment of selected pharmaceuticals present in surface waters in relation to animals

Archives of Environmental Protection

Volumn 37, Issue 3, 2011, Pages 31-42

  Załeska Radziwiłl, Monika ^a   Łlebkowska, Maria ^a   Affek, Katarzyna ^a   Zarzeczna, Agnieszka ^a  

^a WARSAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Aquatic animals; Ciprofloxacin; Ethinylestradiol; Fluorouracil; Risk assessment

Indexed keywords

ANIMALIA; ARTEMIA SALINA; CRUSTACEA; DAPHNIA MAGNA; PROTOZOA;

EID: 82355188349     PISSN: 03248461     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Artoxkit M.: Estuarine and marine waters toxicity screening test. Standard operational procedure, MicroBioTests Inc., Belgium.
2. Berthouex P.M., L.C. Brown: Statistic for environmental engineers, Lewis Publishers, C.R.C. Press Inc. 1994.
3. Commission of the European Communities: Technical guidance document in support of commission directive 93/67/EEC on risk assessment for existing substances. Part II-Environmental risk assessment, Brusssels, Belgium 1996.
4. Daphtoxkit F: Freshwater toxicity screening test. Standard operational procedure, MicroBioTests Inc., Belgium.
5. Espiritu E.Q., C.R. Jansen, G. Persoone: Cyst-based toxicity tests VII. Evaluation of the 1 hour enzymatic inhibition test (Fluotox) with Artemia nauplii, Environmental Toxicology and Water Quality, 10,25-34 (1995).
6. European Medicines Agency (EMEA): Guideline on the environmental risk assessment of medicinal products for human use, EMEA, London 2006.
7. European Medicines Agency (EMEA): Note for Guidance: Environmental risk assessment for veterinary medicinal products other than GMO-containing and immunological products, EMEA, London 1998.
8. Fent K., A.A. Weston, D. Caminada: Ecotoxicology of human pharmaceuticals, Aquatic Toxicology, 76, 122-159(2006).
9. Halling-Søaposrensen B., H.C. Holten Lützhøaposft, H.R. Andersen, F. Ingerslev: Environmental risk assessment of antibiotics: comparison of mecillinam, trimethoprim and ciprofloxacin, Journal of Antimicrobial Chemotherapy, 46,53-58 (2000).
10. Hartmann A., A.C. Alder, T. Koller, R.M. Widmer: Identification of fluoroquinolone antibiotics as the main source of umuC genotoxicity in native hospital wastewater, Environmental Toxicology and Chemistry, 17,377-382 (1998).
11. Hartmann A., E.M. Golet, S. Gartiser, A.C. Alder, T. Koller, R.M. Widmer: Primary DNA damage but not mutagenicity correlates with ciprofloxacin concentrations in German hospital wastewaters, Archives of Environmental Contamination and Toxicology, 36, 115-119 (1999).
12. Jergentz S., M. Goth, C. Seek: Fluorouracil: A study on the chronic toxicity to Daphnia magna according to the OECD Guideline 211, ECT Oekotoxicologie, Flörsheim/Main (DE) and Battelle UK, Ongar (UK) (2009).
13. Khetan S.K., T.J. Collins: Human Pharmaceuticals in the aquatic environment: a challenge to green chemistry, Chemical Reviews, 107,2319-2364 (2007).
14. Kot-Wasik A., J. Dçbska, J. Namieánik: Przemiany, steienia i oznaczanie pozostalošci šrodków farmaceutycznych w środowisku, (in:) Nowe horyzonty i wyzwania w analityce i monitoringu šrodowiskowym, CEEAM, Gdansk 2003, 723-745.
15. Kümmerer K., A. Al-Ahmad, V. Mersch-Sundermann: Biodegradability of some antibiotics, elimination of the genotoxicity and affection of wastewater bacteria in a simple test, Chemosphere, 40, 701-710 (2000).
16. Larsson J.D.G., C. de Pedro, N. Paxeus: Effluent form drug manufactures contains extremely high levels of pharmaceuticals, Journal of Hazardous Material, 148, 751-755 (2007).
17. Łebkowskaebkowska M., M. Zalȩska-Radziwll; Endocrine disruptors - ecotoxicological assays. Archives of Environmental Protection, 33, 81-88 (2007).
18. Łebkowska M.: Wystȩpowanie bakterii antybiotykoopornych w wodzie przeznaczonej do spozycia przez ludzi, Ocnrona Środowiska, 31, 11-15 (2009).
19. Łebkowska M.: Wystepowanie i ekotoksycznošé wybranych leków w šrodowisku wodnym, Prače naukowe Politechniki Warszawskiej, Inžynieria Šrodowiska, 59, 5-11 (2009).
20. Marques CR., N. Abrantes, F. Goncalves: Life-history traits of standard and autochthonous cladocerans. I, II. Acute and chronic effects of acetylsalicylic acid metabolites, Environmental Toxicology, 19, 518-540 (2004).
21. Nash J.P., D.E. Kime, L.T. Van der Ven, P.W. Wester, F. Brion, G. Maack, P. Stahlschmidt-Allner, C.R. Tyler: Long-term exposure to environmental concentrations of the pharmaceutical ethinylestradiol causes reproductive failure in fish, Environmental Health Perspectives, 112, 1725-1733 (2004).
22. Nikolaou A., S. Meric, D. Fatta: Occurrence patterns of pharmaceuticals in water and wastewater environments, Analytical and Bioanalytical Chemistry, 387, 1225-1234 (2007).
23. OECD Guidelines for the testing of chemicals, Test No. 215: Fish, juvenile growth test, OECD, Paris, 2000.
24. OECD Guidelines for the testing of chemicals, test. No. 211 : Daphnia magna reproduction test, OECD, Paris 1998.
25. OECD, Report of the OECD Workshop on the extrapolation of laboratory aquatic toxicity data to the real environment, ENV Monograph No.59 (1992).
26. Parrot J.L., B.R. Blunt: Life-cycle exposure of fathead minnows (Pimephales prometas) to an ethinylestradiol concentration below 1 ng/l reduces egg fertilization success and demasculinizes males, Environmental Toxicology, 20, 131-141 (2005).
27. PN-C-04610-04:1990: Woda i ścieki. Badania toksyczności zanieczyszczeñ dia organizmów wodnych. Oznaczanie toksyeznošci ostrej na gupiku Lebistes reticulatus Peters.
28. Protoxkit F: Freshwater toxicity screening test. Standard operational procedure, MicroBioTests Inc., Belgium.
29. Robinson A.A., J.B. Beiden, M.J. Lydy: Toxicity of fluoroquinolone antibiotics to aquatic organisms, Environmental Toxicology and Chemistry, 24,423-430 (2005).
30. Sanderson H., D.J. Johnson, CJ. Wilson, R.A. Brain, K.R. Solomon: Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and alga by ECOSAR screening, Toxicology Letters, 144,383-395 (2003).
31. Straub J.O.: Combined environmental risk assessment for 5-fluorouracil and capecitabine in Europe, Integrated Environmental Assessment and Management, 6,540-566 (2009).
32. Technical Support Document for Water Quality - based Toxics Control. US Environmental Protection Agency - Office of Water (EN-336) EPA/505/2-90-001 PB 91-127415, 1991.
33. Webb S.F.: A data based perspective on the environmental risk assessment of human pharmaceuticals II: aquatic risk characterization, (in:) Pharmaceuticals in the environment, Springer-Verlag, Heidelberg 2004,317-343.
34. Webb S.F.: A data-based perspective on the environmental risk assessment of human pharmaceuticals I -collation of available ecotoxicity data, (in:) Pharmaceuticals in the environment, Springer-Verlag, Heidelberg 2004,345-361.
35. Weber E.: Grundniss der biologischen Statistok für Naturwissen schaftler, Landwirte und Medizimer, Veb Fischer Verlag, Jena 1972.
36. Zaunková R., P. Odraska, L. Doležalova, K. Hilscherova, B. Marsalek, L. Blaha: Ecotoxicity andgenotoxicity assessment of cytostatic pharmaceuticals. Environmental Toxicology and Chemistry, 26, 2208-2214(2007).