Multifunctional poly(aspartic acid) nanoparticles containing iron oxide nanocrystals and doxorubicin for simultaneous cancer diagnosis and therapy

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 391, Issue 1-3, 2011, Pages 208-215

  Yang, Hee Man ^a   Oh, Byung Chang ^a   Kim, Jong Hun ^a   Ahn, Taebin ^a   Nam, Ho Seong ^a   Park, Chan Woo ^a   Kim, Jong Duk ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Cancer therapy; Doxorubicin; Iron oxide nanocrystals; Magnetic resonance imaging; Poly(aspartic acid)s

Indexed keywords

AMINO ACIDS; DISEASES; DYNAMIC LIGHT SCATTERING; EMULSIFICATION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; IRON; MAGNETIC RESONANCE IMAGING; NANOCRYSTALS; NANOMAGNETICS; NANOPARTICLES; ORGANIC SOLVENTS; TRANSMISSION ELECTRON MICROSCOPY;

ANTICANCER DRUG; CANCER CELLS; CANCER DIAGNOSIS; CANCER THERAPY; DOXORUBICIN; DRUG RELEASE; EMULSION METHOD; HIGH-T; IRON OXIDE NANOCRYSTALS; LOADING EFFICIENCY; MR IMAGING; MTT ASSAYS; OCTADECYL; POLY(ASPARTIC ACID); RELAXIVITY;

IRON OXIDES;

ASPARTIC ACID; ASPARTIC ACID DERIVATIVE; DOXORUBICIN; IRON OXIDE; IRON OXIDE NANOCRYSTAL; NANOPARTICLE; ORGANIC SOLVENT; POLY(ASPARTIC ACID)NANOPARTICLE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER DIAGNOSIS; CANCER THERAPY; CONTROLLED STUDY; DRUG RELEASE; EMULSION; HUMAN; HUMAN CELL; HYDROPHOBICITY; INFRARED SPECTROSCOPY; LIGHT SCATTERING; PARTICLE SIZE; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

EID: 82355182749     PISSN: 09277757     EISSN: 18734359     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2011.04.032     Document Type: Article

References (26)

1. Hao R., Xing R., Xu Z., Hou Y., Gao S., Sun S. Synthesis, functionalization, and biomedical applications of multifunctional magnetic nanoparticles. Adv. Mater. 2010, 22:2729-2742.
2. Fang C., Zhang M. Multifunctional magnetic nanoparticles for medical imaging applications. J. Mater. Chem. 2009, 19:6258-6266.
3. Hu F.X., Neoh K.G., Kang E.T. Synthesis and in vitro anti-cancer evaluation of tamoxifen-loaded magnetite/PLLA composite nanoparticles. Biomaterials 2006, 27:5725-5733.
4. Yang J., Park S.-B., Yoon H.-G., Huh Y.-M., Haam S. Preparation of poly-caprolactone nanoparticles containing magnetite for magnetic drug carrier. Int. J. Pharm. 2006, 324:185-190.
5. Yang J., Lee C.-H., Park J., Seo S., Lim E.-K., Song Y.J., Suh J.-S., Yoon H.-G., Huh Y.-M., Haam S. Antibody conjugated magnetic PLGA nanoparticles for diagnosis and treatment of breast cancer. J. Mater. Chem. 2007, 17:2695-2699.
6. Kim J., Lee J.E., Lee S.H., Yu J.H., Lee J.H., Park T.G., Hyeon T. Designed fabrication of a multifunctional polymer nanomedical platform for simultaneous cancer-targeted imaging and magnetically guided drug delivery. Adv. Mater. 2008, 20:478-483.
7. Jain T.K., Morales M.A., Sahoo S.K., Leslie-Pelecky D.L., Labhasetwar V. Iron oxide nanoparticles for sustained delivery of anticancer agents. Mol. Pharm. 2005, 2(3):194-205.
8. Yang J., Lee C.-H., Ko H.-j., Suh J.-S., Yoon H.-G., Lee K., Huh Y.-M., Haam S. Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer. Angew. Chem. Int. Ed. 2007, 46:8836-8839.
9. Nasongkla N., Bey E., Ren J., Ai H., Khemtong C., Guthi J.S., Chin S.-F., Sherry A.D., Boothman D.A., Gao J. Multifunctional polymeric micelles as cancer-targeted, mri-ultrasensitive drug delivery systems. Nano Lett. 2006, 6(11):2427-2430.
10. Drobnik J. Biodegradable soluble macromolecules as drug carriers. Adv. Drug Deliv. Rev. 1989, 3:229-245.
11. Caldwell G., Neuse N.W., Perlwitz A.G. Water soluble polyamides as potential drug carriers. IX. Polyaspartamides grafted with amine-terminated poly(ethylene oxide) chains. J. Appl. Polym. Sci. 1997, 66:911-918.
12. Kang H.S., Yang S.R., Kim J.-D., Han S.-H., Chang I.-S. Effects of grafted alkyl groups on aggregation behavior of amphiphilic poly(aspartic acid). Langmuir 2001, 17:7501-7506.
13. Lee H.-Y., Li Z., Chen K., Hsu A.R., Xu C., Xie J., Sun S., Chen X. PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles. J. Nucl. Med. 2008, 49(8):1371-1379.
14. Kumagai M., Kano M.R., Morishita Y., Ota M., Imai Y., Nishiyama N., Sekino M., Ueno S., Miyazono K., Kataoka K. Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block copolymer-coated magnetite nanoparticles with TGF-β inhibitor. J. Controlled Release 2009, 140:306-311.
15. Qiao R., Yang C., Gao M. Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications. J. Mater. Chem. 2009, 19:6274-6293.
16. Chen K., Xie J., Xu H., Behera D., Michalski M.H., Biswal S., Wang A., Chen X. Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting. Biomaterials 2009, 30:6912-6919.
17. Yang H.-M., Lee H.J., Jang K.-S., Park C.W., Yang H.W., Heo W.D., Kim J.-D. Poly(amino acid)-coated iron oxide nanoparticles as ultra-small magnetic resonance probes. J. Mater. Chem. 2009, 19:4566-4574.
18. Yang H.-M., Park C.W., Woo M.-A., Kim M.I., Jo Y.M., Park H.G., Kim J.-D. HER2/neu antibody conjugated poly(amino acid)-coated iron oxide nanoparticles for breast cancer MR imaging. Biomacromolecules 2010, 11:2866-2872.
19. Lee H.J., Jang K.-S., Jang S., Kim J.W., Yang H.-M., Jeong Y.Y., Kim J.-D. Poly(amino acid)s micelle-mediated assembly of magnetite nanoparticles for ultra-sensitive long-term MR imaging of tumors. Chem. Commun. 2010, 46:3559-3561.
20. Yang H.-M., Lee H.J., Park C.W., Yoon S.R., Lim S., Jung B.H., Kim J.-D. Endosome-escapable magnetic poly(amino acid) nanoparticles for cancer diagnosis and therapy. Chem. Commun. 2011, 47:5322-5324.
21. 4 (M=Fe, Co, Mn) nanoparticles. J. Am. Chem. Soc. 2004, 126:273-279.
22. Yang S.R., Kim S.B., Joe C.O., Kim J.-D. Self-aggregates of oligoarginine-conjugated poly(amino acid) derivatives as a carrier for intracellular drug delivery. Biotechnol. Lett. 2005, 27:977-982.
23. Zhang J.L., Srivastava R.S., Misra R.D.K. Core-shell magnetite nanoparticles surface encapsulated with smart stimuli-responsive polymer: synthesis, characterization, and lcst of viable drug-targeting delivery system. Langmuir 2007, 23:6342-6351.
24. Yang S.R, Lee H.J., Kim J.-D. Histidine-conjugated poly(amino acid) derivatives for the novel endosomolytic delivery carrier of doxorubicin. J. Controlled Release 2006, 114:60-68.
25. Okon E., Pouliquen D., Okon P., Kovaleva Z.V., Stepanova T.P., Lavit S.G., Kudryavtsev B.N., Jallet P. Biodegradation of magnetite dextran nanoparticles in the rat. A histologic and biophysical study. Lab Invest. 1994, 71(6):895-903.
26. Jain T.K., Reddy M.K., Morales M.A., Leslie-Pelecky D.L., Labhasetwar V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol. Pharm. 2008, 5(2):316-327.